PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 5GS2

#CDRs = 8; #Clusters = 12.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
D	kappa	Mus.musculus	Hu_IGKV1D-13*01	97.1	Hu_IGKV1D-13*01	72.7	L1	11	L1-11-*	-1	RASQSVSSAVA	BBABBBBBABB
D	kappa	Mus.musculus	Hu_IGKV1D-13*01	97.1	Hu_IGKV1D-13*01	75.0	L2	8	L2-8-1	14	YSASSLYS	BLLABBBB
D	kappa	Mus.musculus	Hu_IGKV1D-13*01	97.1	Hu_IGKV1D-13*01	28.6	L3	9	L3-9-cis7-1	18	QQSSSSLIT	BBAABBbBB
D	kappa	Mus.musculus	Hu_IGKV1D-13*01	97.1	Hu_IGKV1D-13*01	83.3	L4	6	L4-6-2	20	RSGTDF	BBEABB
D	heavy	Mus.musculus	Mo_IGHV1-14*01	91.8	Mo_IGHV1-14*01	92.3	H1	13	H1-13-1	20	KASGYTFTSYVIH	BBBLBBAAABBBB
D	heavy	Mus.musculus	Mo_IGHV1-14*01	91.8	Mo_IGHV1-14*01	80.0	H2	10	H2-10-*	-1	YINPYNDGSK	BBBAAAbBBB
D	heavy	Mus.musculus	Mo_IGHV1-14*01	91.8	Mo_IGHV1-14*01	100.0	H3	14	H3-14-*	-1	ARYGVRGDYYAVDY	BBBBBAEABBBAEB
D	heavy	Mus.musculus	Mo_IGHV1-14*01	91.8	Mo_IGHV1-14*01	100.0	H4	8	H4-8-1	7	SDKSSSTA	BBAAALBB
H	heavy	Homo.sapiens	Hu_IGHV3-23*04	93.2	Hu_IGHV3-23*04	61.5	H1	13	H1-13-1	12	AASGFNFSSSSIH	BBBLBBAAABBBB
H	heavy	Homo.sapiens	Hu_IGHV3-23*04	93.2	Hu_IGHV3-23*04	60.0	H2	10	H2-10-1	14	SISSSSGSTS	BBBAAALBBB
H	heavy	Homo.sapiens	Hu_IGHV3-23*04	93.2	Hu_IGHV3-23*04	50.0	H3	20	H3-20-*	-1	ARYGHWswgrwwNYWVALDY
H	heavy	Homo.sapiens	Hu_IGHV3-23*04	93.2	Hu_IGHV3-23*04	62.5	H4	8	H4-8-1	8	ADTSKNTA	BBAAALBB
H	kappa	Homo.sapiens	Mo_IGKV6-14*01	98.6	Mo_IGKV6-14*01	100.0	L1	11	L1-11-*	-1	KASQNVRTAVA	BBABBBBLBBB
H	kappa	Homo.sapiens	Mo_IGKV6-14*01	98.6	Mo_IGKV6-14*01	100.0	L2	8	L2-8-*	-1	YLASNRHT	BLEBBBBB
H	kappa	Homo.sapiens	Mo_IGKV6-14*01	98.6	Mo_IGKV6-14*01	85.7	L3	9	L3-9-cis7-1	16	LQHWSYPYT	BBAABBbBB
H	kappa	Homo.sapiens	Mo_IGKV6-14*01	98.6	Mo_IGKV6-14*01	100.0	L4	6	L4-6-1	10	GSGTDF	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022