PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 5GS1

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Ra_IGKV4S21*01	75.0	L1	12	L1-12-2	4	RASQSVSsNYLA	BBABBBBLLBBB
A	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Ra_IGKV4S21*01	50.0	L2	8	L2-8-1	4	YDSSSRAT	BLLABBBB
A	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Hu_IGKV3-11*01	28.6	L3	9	L3-9-2	16	HQYSDISPT	BBAABABBB
A	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Hu_IGKV3-11*01	100.0	L4	6	L4-6-1	6	GSGTDF	EBEABB
B	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Ra_IGHV5-19*01	76.9	H1	13	H1-13-1	10	AASGFTFRNSAMH	BBBLBBAAABBBB
B	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Ra_IGHV5-19*01	60.0	H2	10	H2-10-*	-1	SIWYSGSNTY	BBBBBLBBBB
B	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Hu_IGHV3-66*01	100.0	H3	12	H3-12-*	-1	ARFAGGWGAYDV	BBBAEAALEBAB
B	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Hu_IGHV3-66*01	100.0	H4	8	H4-8-1	2	RDNSKNTL	BBAAALBB
C	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Ra_IGHV5-19*01	76.9	H1	13	H1-13-1	11	AASGFTFRNSAMH	BBBLBBAAABBBB
C	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Ra_IGHV5-19*01	60.0	H2	10	H2-10-*	-1	SIWYSGSNTY	BBBBBLBBBB
C	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Hu_IGHV3-66*01	100.0	H3	12	H3-12-*	-1	ARFAGGWGAYDV	BBBAEAALEBAB
C	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Hu_IGHV3-66*01	100.0	H4	8	H4-8-1	4	RDNSKNTL	BBAAALBB
C	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Ra_IGKV4S21*01	75.0	L1	12	L1-12-2	4	RASQSVSsNYLA	BBABBBBLLBBB
C	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Ra_IGKV4S21*01	50.0	L2	8	L2-8-1	5	YDSSSRAT	BLLABBBB
C	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Hu_IGKV3-11*01	28.6	L3	9	L3-9-2	19	HQYSDISPT	BBAABABBB
C	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Hu_IGKV3-11*01	100.0	L4	6	L4-6-1	6	GSGTDF	EBEABB
D	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Ra_IGKV4S21*01	75.0	L1	12	L1-12-2	5	RASQSVSsNYLA	BBABBBBLLBBB
D	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Ra_IGKV4S21*01	50.0	L2	8	L2-8-1	4	YDSSSRAT	BLLABBBB
D	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Hu_IGKV3-11*01	28.6	L3	9	L3-9-2	20	HQYSDISPT	BBAABABBB
D	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Hu_IGKV3-11*01	100.0	L4	6	L4-6-1	6	GSGTDF	EBEABB
D	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Ra_IGHV5-19*01	76.9	H1	13	H1-13-1	8	AASGFTFRNSAMH	BBBLBBAAABBBB
D	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Ra_IGHV5-19*01	60.0	H2	10	H2-10-*	-1	SIWYSGSNTY	BBBBABBBBB
D	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Hu_IGHV3-66*01	100.0	H3	12	H3-12-*	-1	ARFAGGWGAYDV	BBBAEAALEBAB
D	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Hu_IGHV3-66*01	100.0	H4	8	H4-8-1	4	RDNSKNTL	BBAAALBB
E	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Ra_IGHV5-19*01	76.9	H1	13	H1-13-1	10	AASGFTFRNSAMH	BBBLBBAAABBBB
E	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Ra_IGHV5-19*01	60.0	H2	10	H2-10-*	-1	SIWYSGSNTY	BBBBBLBBBB
E	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Hu_IGHV3-66*01	100.0	H3	12	H3-12-*	-1	ARFAGGWGAYDV	BBBAEAALEBAB
E	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Hu_IGHV3-66*01	100.0	H4	8	H4-8-1	5	RDNSKNTL	BBAAALBB
E	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Ra_IGKV4S21*01	75.0	L1	12	L1-12-2	4	RASQSVSsNYLA	BBABBBBLLBBB
E	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Ra_IGKV4S21*01	50.0	L2	8	L2-8-1	5	YDSSSRAT	BLLABBBB
E	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Hu_IGKV3-11*01	28.6	L3	9	L3-9-2	17	HQYSDISPT	BBAABABBB
E	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Hu_IGKV3-11*01	100.0	L4	6	L4-6-1	8	GSGTDF	EBEABB
F	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Ra_IGKV4S21*01	75.0	L1	12	L1-12-2	4	RASQSVSsNYLA	BBABBBBLLBBB
F	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Ra_IGKV4S21*01	50.0	L2	8	L2-8-1	5	YDSSSRAT	BLLABBBB
F	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Hu_IGKV3-11*01	28.6	L3	9	L3-9-2	20	HQYSDISPT	BBAABABBB
F	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Hu_IGKV3-11*01	100.0	L4	6	L4-6-1	8	GSGTDF	EBEABB
F	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Ra_IGHV5-19*01	76.9	H1	13	H1-13-1	10	AASGFTFRNSAMH	BBBLBBAAABBBB
F	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Ra_IGHV5-19*01	60.0	H2	10	H2-10-*	-1	SIWYSGSNTY	BBBBABBBBB
F	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Hu_IGHV3-66*01	100.0	H3	12	H3-12-*	-1	ARFAGGWGAYDV	BBBAEAALEBAB
F	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Hu_IGHV3-66*01	100.0	H4	8	H4-8-1	5	RDNSKNTL	BBAAALBB
G	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Ra_IGKV4S21*01	75.0	L1	12	L1-12-2	5	RASQSVSsNYLA	BBABBBBLLBBB
G	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Ra_IGKV4S21*01	50.0	L2	8	L2-8-1	6	YDSSSRAT	BLLABBBB
G	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Hu_IGKV3-11*01	28.6	L3	9	L3-9-2	18	HQYSDISPT	BBAABABBB
G	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Hu_IGKV3-11*01	100.0	L4	6	L4-6-1	8	GSGTDF	EBEABB
G	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Ra_IGHV5-19*01	76.9	H1	13	H1-13-1	12	AASGFTFRNSAMH	BBBLBBAAABBBB
G	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Ra_IGHV5-19*01	60.0	H2	10	H2-10-*	-1	SIWYSGSNTY	BBBBBLBBBB
G	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Hu_IGHV3-66*01	100.0	H3	12	H3-12-*	-1	ARFAGGWGAYDV	BBBAEAALEBAB
G	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Hu_IGHV3-66*01	100.0	H4	8	H4-8-1	5	RDNSKNTL	BBAAALBB
H	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Ra_IGHV5-19*01	76.9	H1	13	H1-13-1	12	AASGFTFRNSAMH	BBBLBBAAABBBB
H	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Ra_IGHV5-19*01	60.0	H2	10	H2-10-*	-1	SIWYSGSNTY	BBBBBlBBBB
H	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Hu_IGHV3-66*01	100.0	H3	12	H3-12-*	-1	ARFAGGWGAYDV	BBBAEAALEBAB
H	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Hu_IGHV3-66*01	100.0	H4	8	H4-8-1	5	RDNSKNTL	BBAAALBB
H	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Ra_IGKV4S21*01	75.0	L1	12	L1-12-2	4	RASQSVSsNYLA	BBABBBBLLBBB
H	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Ra_IGKV4S21*01	50.0	L2	8	L2-8-1	5	YDSSSRAT	BLLABBBB
H	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Hu_IGKV3-11*01	28.6	L3	9	L3-9-2	18	HQYSDISPT	BBAABABBB
H	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Hu_IGKV3-11*01	100.0	L4	6	L4-6-1	7	GSGTDF	EBEABB
I	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Ra_IGHV5-19*01	76.9	H1	13	H1-13-1	11	AASGFTFRNSAMH	BBBLBBAAABBBB
I	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Ra_IGHV5-19*01	60.0	H2	10	H2-10-*	-1	SIWYSGSNTY	BBBBBLBBBB
I	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Hu_IGHV3-66*01	100.0	H3	12	H3-12-*	-1	ARFAGGWGAYDV	BBBAEAALEBAB
I	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Hu_IGHV3-66*01	100.0	H4	8	H4-8-1	5	RDNSKNTL	BBAAALBB
I	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Ra_IGKV4S21*01	75.0	L1	12	L1-12-2	4	RASQSVSsNYLA	BBABBBBLLBBB
I	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Ra_IGKV4S21*01	50.0	L2	8	L2-8-1	5	YDSSSRAT	BLLABBBB
I	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Hu_IGKV3-11*01	28.6	L3	9	L3-9-2	18	HQYSDISPT	BBAABABBB
I	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Hu_IGKV3-11*01	100.0	L4	6	L4-6-1	8	GSGTDF	EBEABB
J	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Ra_IGKV4S21*01	75.0	L1	12	L1-12-2	6	RASQSVSsNYLA	BBABBBBLLBBB
J	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Ra_IGKV4S21*01	50.0	L2	8	L2-8-1	5	YDSSSRAT	BLLABBBB
J	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Hu_IGKV3-11*01	28.6	L3	9	L3-9-2	17	HQYSDISPT	BBAABABBB
J	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Hu_IGKV3-11*01	100.0	L4	6	L4-6-1	7	GSGTDF	EBEABB
J	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Ra_IGHV5-19*01	76.9	H1	13	H1-13-1	11	AASGFTFRNSAMH	BBBLBBAAABBBB
J	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Ra_IGHV5-19*01	60.0	H2	10	H2-10-*	-1	SIWYSGSNTY	BBBBBLBBBB
J	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Hu_IGHV3-66*01	100.0	H3	12	H3-12-*	-1	ARFAGGWGAYDV	BBBAEAALEBAB
J	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Hu_IGHV3-66*01	100.0	H4	8	H4-8-1	5	RDNSKNTL	BBAAALBB
K	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Ra_IGKV4S21*01	75.0	L1	12	L1-12-2	4	RASQSVSsNYLA	BBABBBBLLBBB
K	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Ra_IGKV4S21*01	50.0	L2	8	L2-8-1	5	YDSSSRAT	BLLABBBB
K	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Hu_IGKV3-11*01	28.6	L3	9	L3-9-2	18	HQYSDISPT	BBAABABBB
K	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Hu_IGKV3-11*01	100.0	L4	6	L4-6-1	8	GSGTDF	EBEABB
K	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Ra_IGHV5-19*01	76.9	H1	13	H1-13-1	11	AASGFTFRNSAMH	BBBLBBAAABBBB
K	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Ra_IGHV5-19*01	60.0	H2	10	H2-10-*	-1	SIWYSGSNTY	BBBBBLBBBB
K	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Hu_IGHV3-66*01	100.0	H3	12	H3-12-*	-1	ARFAGGWGAYDV	BBBAEAALEBAB
K	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Hu_IGHV3-66*01	100.0	H4	8	H4-8-1	6	RDNSKNTL	BBAAALBB
L	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Ra_IGHV5-19*01	76.9	H1	13	H1-13-1	10	AASGFTFRNSAMH	BBBLBBAAABBBB
L	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Ra_IGHV5-19*01	60.0	H2	10	H2-10-*	-1	SIWYSGSNTY	BBBBAABBBB
L	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Hu_IGHV3-66*01	100.0	H3	12	H3-12-*	-1	ARFAGGWGAYDV	BBBAEAALEBAB
L	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Hu_IGHV3-66*01	100.0	H4	8	H4-8-1	6	RDNSKNTL	BBAAALBB
L	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Ra_IGKV4S21*01	75.0	L1	12	L1-12-2	4	RASQSVSsNYLA	BBABBBBLLBBB
L	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Ra_IGKV4S21*01	50.0	L2	8	L2-8-1	5	YDSSSRAT	BLLABBBB
L	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Hu_IGKV3-11*01	28.6	L3	9	L3-9-2	18	HQYSDISPT	BBAABABBB
L	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Hu_IGKV3-11*01	100.0	L4	6	L4-6-1	7	GSGTDF	EBEABB
M	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Ra_IGKV4S21*01	75.0	L1	12	L1-12-2	4	RASQSVSsNYLA	BBABBBBLLBBB
M	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Ra_IGKV4S21*01	50.0	L2	8	L2-8-1	4	YDSSSRAT	BLLABBBB
M	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Hu_IGKV3-11*01	28.6	L3	9	L3-9-2	16	HQYSDISPT	BBAABABBB
M	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Hu_IGKV3-11*01	100.0	L4	6	L4-6-1	6	GSGTDF	EBEABB
N	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Ra_IGHV5-19*01	76.9	H1	13	H1-13-1	11	AASGFTFRNSAMH	BBBLBBAAABBBB
N	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Ra_IGHV5-19*01	60.0	H2	10	H2-10-*	-1	SIWYSGSNTY	BBBBBLBBBB
N	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Hu_IGHV3-66*01	100.0	H3	12	H3-12-*	-1	ARFAGGWGAYDV	BBBAEAALEBAB
N	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Hu_IGHV3-66*01	100.0	H4	8	H4-8-1	3	RDNSKNTL	BBAAALBB
O	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Ra_IGKV4S21*01	75.0	L1	12	L1-12-2	4	RASQSVSsNYLA	BBABBBBLLBBB
O	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Ra_IGKV4S21*01	50.0	L2	8	L2-8-1	4	YDSSSRAT	BLLABBBB
O	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Hu_IGKV3-11*01	28.6	L3	9	L3-9-2	16	HQYSDISPT	BBAABABBB
O	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Hu_IGKV3-11*01	100.0	L4	6	L4-6-1	6	GSGTDF	EBEABB
P	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Ra_IGHV5-19*01	76.9	H1	13	H1-13-1	11	AASGFTFRNSAMH	BBBLBBAAABBBB
P	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Ra_IGHV5-19*01	60.0	H2	10	H2-10-*	-1	SIWYSGSNTY	BBBBBLBBBB
P	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Hu_IGHV3-66*01	100.0	H3	12	H3-12-*	-1	ARFAGGWGAYDV	BBBAEAALEBAB
P	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Hu_IGHV3-66*01	100.0	H4	8	H4-8-1	2	RDNSKNTL	BBAAALBB
Q	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Ra_IGKV4S21*01	75.0	L1	12	L1-12-2	4	RASQSVSsNYLA	BBABBBBLLBBB
Q	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Ra_IGKV4S21*01	50.0	L2	8	L2-8-1	4	YDSSSRAT	BLLABBBB
Q	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Hu_IGKV3-11*01	28.6	L3	9	L3-9-2	16	HQYSDISPT	BBAABABBB
Q	kappa	Homo.sapiens	Hu_IGKV3-11*01	97.1	Hu_IGKV3-11*01	100.0	L4	6	L4-6-1	6	GSGTDF	EBEABB
R	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Ra_IGHV5-19*01	76.9	H1	13	H1-13-1	11	AASGFTFRNSAMH	BBBLBBAAABBBB
R	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Ra_IGHV5-19*01	60.0	H2	10	H2-10-*	-1	SIWYSGSNTY	BBBBBLBBBB
R	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Hu_IGHV3-66*01	100.0	H3	12	H3-12-*	-1	ARFAGGWGAYDV	BBBAEAALEBAB
R	heavy	Homo.sapiens	Hu_IGHV3-66*01	98.6	Hu_IGHV3-66*01	100.0	H4	8	H4-8-1	2	RDNSKNTL	BBAAALBB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022