PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 5FCS

#CDRs = 8; #Clusters = 15.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
H	lambda	Homo.sapiens	Hu_IGLV7-46*02	91.2	Hu_IGLV7-46*02	57.1	L1	14	L1-14-1	4	RSSTGAVTtSNYAN	BBAAEBBBAAALBB
H	lambda	Homo.sapiens	Hu_IGLV7-46*02	91.2	Hu_IGLV7-46*02	12.5	L2	8	L2-8-*	-1	GGTNKRAP	BLEABBBA
H	lambda	Homo.sapiens	Hu_IGLV7-46*02	91.2	Hu_IGLV7-46*02	37.5	L3	9	L3-9-4	8	ALWYSNLWV	BBBBEABBB
H	lambda	Homo.sapiens	Hu_IGLV7-46*02	91.2	Hu_IGLV7-46*02	100.0	L4	6	L4-6-*	-1	LLGGKA	BBLLBB
H	heavy	Homo.sapiens	Hu_IGHV1-18*01	98.6	Hu_IGHV1-18*01	100.0	H1	13	H1-13-*	-1	KASGYTFTSYGIS	BBBEBBAAABBBB
H	heavy	Homo.sapiens	Hu_IGHV1-18*01	98.6	Hu_IGHV1-18*01	100.0	H2	10	H2-10-1	10	WISAYNGNTN	BBBAAALBBB
H	heavy	Homo.sapiens	Hu_IGHV1-18*01	98.6	Hu_IGHV1-18*01	50.0	H3	11	H3-11-1	12	ATIDTASAFDI	BBBBAALBBAB
H	heavy	Homo.sapiens	Hu_IGHV1-18*01	98.6	Hu_IGHV1-18*01	100.0	H4	8	H4-8-1	7	TDTSTSTA	BBAAALBB
L	heavy	Homo.sapiens	Hu_IGHV3-73*01	90.4	Hu_IGHV3-73*01	69.2	H1	13	H1-13-1	8	AASGFTFNTYAMN	BBBLBBAAABBBB
L	heavy	Homo.sapiens	Hu_IGHV3-73*01	90.4	Hu_IGHV3-73*01	75.0	H2	12	H2-12-1	10	RIRSKynNYATY	BBBBAAALLBBB
L	heavy	Homo.sapiens	Hu_IGHV3-73*01	90.4	Hu_IGHV3-73*01	50.0	H3	16	H3-16-*	-1	VRHGNfgNSYVSWFAY
L	heavy	Homo.sapiens	Hu_IGHV3-73*01	90.4	Hu_IGHV3-73*01	75.0	H4	8	H4-8-1	5	RDDSKNSL	BBAAALBB
L	lambda	Homo.sapiens	Hu_IGLV1-51*01	100.0	Hu_IGLV1-51*01	100.0	L1	13	L1-13-1	8	SGSSSNIGNNYVS	BBBAAAAAABBBB
L	lambda	Homo.sapiens	Hu_IGLV1-51*01	100.0	Hu_IGLV1-51*01	100.0	L2	8	L2-8-1	6	YDNNKRPS	BLLABBBB
L	lambda	Homo.sapiens	Hu_IGLV1-51*01	100.0	Hu_IGLV1-51*01	100.0	L3	11	L3-11-1	6	GTWDSSLSAVV	BBBBAAALBBB
L	lambda	Homo.sapiens	Hu_IGLV1-51*01	100.0	Hu_IGLV1-51*01	100.0	L4	6	L4-6-2	7	KSGTSA	BBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022