PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 5EZJ

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	heavy	Homo.sapiens	Mo_IGHV4-2*02	97.2	Mo_IGHV4-2*02	100.0	H1	13	H1-13-1	8	AASGFDFSRYWMS	BBBLBBAAABBBB
A	heavy	Homo.sapiens	Mo_IGHV4-2*02	97.2	Mo_IGHV4-2*02	90.0	H2	10	H2-10-2	8	EINPGSSTIK	BBBAALABBB
A	heavy	Homo.sapiens	Mo_IGHV4-2*02	97.2	Mo_IGHV4-2*02	100.0	H3	12	H3-12-3	15	ARYGSYVYAMDY	BBBBBLBBBBAB
A	heavy	Homo.sapiens	Mo_IGHV4-2*02	97.2	Mo_IGHV4-2*02	100.0	H4	8	H4-8-1	6	RDNAKNTL	BBAAALBB
B	kappa	Homo.sapiens	Mo_IGKV6-32*01	97.1	Mo_IGKV6-32*01	90.9	L1	11	L1-11-1	7	KASQSVRNDVA	BBABBAEABBB
B	kappa	Homo.sapiens	Mo_IGKV6-32*01	97.1	Mo_IGKV6-32*01	87.5	L2	8	L2-8-1	7	YFASNRYT	BLLABBBB
B	kappa	Homo.sapiens	Mo_IGKV6-32*01	97.1	Mo_IGKV6-32*01	71.4	L3	9	L3-9-cis7-1	18	QQGYTSPRT	BBAABBbBB
B	kappa	Homo.sapiens	Mo_IGKV6-32*01	97.1	Mo_IGKV6-32*01	83.3	L4	6	L4-6-1	7	GSGTDF	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022