PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 5EU7

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
C	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Mo_IGKV6-17*01	72.7	L1	11	L1-11-1	8	RASQSVSSAVA	BBABBAEABBB
C	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Mo_IGKV6-17*01	62.5	L2	8	L2-8-1	11	YSASSLYS	BLEABBBB
C	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	57.1	L3	9	L3-9-cis7-1	8	QQSSYSPLT	BBAABBbBB
C	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	83.3	L4	6	L4-6-2	7	RSGTDF	BBEABB
D	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Mo_IGKV6-17*01	72.7	L1	11	L1-11-1	8	RASQSVSSAVA	BBABBAEABBB
D	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Mo_IGKV6-17*01	62.5	L2	8	L2-8-1	11	YSASSLYS	BLEABBBB
D	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	57.1	L3	9	L3-9-cis7-1	8	QQSSYSPLT	BBAABBbBB
D	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	83.3	L4	6	L4-6-2	7	RSGTDF	BBEABB
E	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Mo_IGHV1S22*01	53.8	H1	13	H1-13-1	10	AASGFNLYSYSMH	BBBLBBAAABBBB
E	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Mo_IGHV1S22*01	70.0	H2	10	H2-10-1	14	YIYPYSGSTS	BBBAAALBBB
E	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	100.0	H3	23	H3-23-*	-1	ARESsyfydgsysYYDYEGAMDY
E	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	62.5	H4	8	H4-8-1	6	ADTSKNTA	BBAAALBB
F	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Mo_IGHV1S22*01	53.8	H1	13	H1-13-1	10	AASGFNLYSYSMH	BBBLBBAAABBBB
F	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Mo_IGHV1S22*01	70.0	H2	10	H2-10-1	14	YIYPYSGSTS	BBBAAALBBB
F	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	100.0	H3	23	H3-23-*	-1	ARESsyfydgsysYYDYEGAMDY
F	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	62.5	H4	8	H4-8-1	7	ADTSKNTA	BBAAALBB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022