PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 5EII

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Ca_IGHV1S29*01	53.8	H1	13	H1-13-1	12	AASGFNISYSSIH	BBBLBBAAABBBB
A	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Ca_IGHV1S29*01	60.0	H2	10	H2-10-1	7	SISSYYGSTY	BBBAAALBBB
A	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	100.0	H3	17	H3-17-*	-1	ARSRGQaswDYWWAMDY
A	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	62.5	H4	8	H4-8-1	5	ADTSKNTA	BBAAALBB
B	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Ca_IGKV1-26*01	63.6	L1	11	L1-11-1	6	RASQSVSSAVA	BBABBAEABBB
B	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Ca_IGKV1-26*01	75.0	L2	8	L2-8-1	4	YSASSLYS	BLLABBBB
B	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	57.1	L3	9	L3-9-cis7-1	12	QQSSDDPIT	BBAABBbBB
B	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	83.3	L4	6	L4-6-2	12	RSGTDF	BBEABB
H	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Ca_IGHV1S29*01	53.8	H1	13	H1-13-1	12	AASGFNISYSSIH	BBBLBBAAABBBB
H	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Ca_IGHV1S29*01	60.0	H2	10	H2-10-1	13	SISSYYGSTY	BBBAAALBBB
H	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	100.0	H3	17	H3-17-*	-1	ARSRGQaswDYWWAMDY
H	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	62.5	H4	8	H4-8-1	6	ADTSKNTA	BBAAALBB
L	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Ca_IGKV1-26*01	63.6	L1	11	L1-11-1	8	RASQSVSSAVA	BBABBAEABBB
L	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Ca_IGKV1-26*01	75.0	L2	8	L2-8-1	5	YSASSLYS	BLLABBBB
L	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	57.1	L3	9	L3-9-cis7-1	9	QQSSDDPIT	BBAABBbBB
L	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	83.3	L4	6	L4-6-2	12	RSGTDF	BBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022