PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 5D1Z

#CDRs = 8; #Clusters = 13.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	kappa	Homo.sapiens	Hu_IGKV1-9*01	94.2	Hu_IGKV1-9*01	72.7	L1	11	L1-11-1	12	RASQGITTYLG	BBABBAEABBB
A	kappa	Homo.sapiens	Hu_IGKV1-9*01	94.2	Hu_IGKV1-9*01	87.5	L2	8	L2-8-1	12	YAASSLQS	BLLABBBB
A	kappa	Homo.sapiens	Hu_IGKV1-9*01	94.2	Hu_IGKV1-9*01	85.7	L3	9	L3-9-cis7-1	19	QQLNTYPYT	BBAABBbBB
A	kappa	Homo.sapiens	Hu_IGKV1-9*01	94.2	Hu_IGKV1-9*01	100.0	L4	6	L4-6-1	21	GSGTEF	EBEABB
B	heavy	Homo.sapiens	Hu_IGHV3-7*01	95.9	Hu_IGHV3-7*01	69.2	H1	13	H1-13-1	11	AASGFTFNKFWMN	BBBLBBAAABBBB
B	heavy	Homo.sapiens	Hu_IGHV3-7*01	95.9	Hu_IGHV3-7*01	60.0	H2	10	H2-10-2	15	DIQVDGSEKN	BBBAALABBB
B	heavy	Homo.sapiens	Hu_IGHV3-7*01	95.9	Hu_IGHV3-7*01	100.0	H3	14	H3-14-*	-1	ARGRYDYWSGYLSP	BBBABBLBBEBBBb
B	heavy	Homo.sapiens	Hu_IGHV3-7*01	95.9	Hu_IGHV3-7*01	87.5	H4	8	H4-8-1	15	RDNGKNSL	BBAAALBB
C	kappa	Homo.sapiens	Hu_IGKV1-9*01	91.3	Hu_IGKV1-9*01	63.6	L1	11	L1-11-1	12	RASQAVRSSLA	BBABBAEABBB
C	kappa	Homo.sapiens	Hu_IGKV1-9*01	91.3	Hu_IGKV1-9*01	62.5	L2	8	L2-8-1	10	YSASTLEN	BLLABBBB
C	kappa	Homo.sapiens	Hu_IGKV1-9*01	91.3	Hu_IGKV1-9*01	85.7	L3	9	L3-9-cis7-1	17	QQLNTYPFT	BBAABBbBB
C	kappa	Homo.sapiens	Hu_IGKV1-9*01	91.3	Hu_IGKV1-9*01	83.3	L4	6	L4-6-*	-1	GPGTEF	EbEABB
D	heavy	Homo.sapiens	Hu_IGHV4-39*03	79.2	Hu_IGHV4-39*03	100.0	H1	15	H1-15-*	-1	TVSGGSIssSSYYWG	BABLLBALBABABBB
D	heavy	Homo.sapiens	Hu_IGHV4-39*03	79.2	Hu_IGHV4-39*03	66.7	H2	9	H2-9-1	11	IIYFSGTTY	BBBAALBBB
D	heavy	Homo.sapiens	Hu_IGHV4-39*03	79.2	Hu_IGHV4-39*03	0.0	H3	20	H3-20-*	-1	AKPKSRdrggpgDDYFGMDV
D	heavy	Homo.sapiens	Hu_IGHV4-39*03	79.2	Hu_IGHV4-39*03	50.0	H4	8	H4-8-1	13	LDRSTNRF	BBAAALBB
E	kappa	Homo.sapiens	Hu_IGKV1-9*01	91.3	Hu_IGKV1-9*01	63.6	L1	11	L1-11-1	12	RASQAVRSSLA	BBABBAEABBB
E	kappa	Homo.sapiens	Hu_IGKV1-9*01	91.3	Hu_IGKV1-9*01	62.5	L2	8	L2-8-1	10	YSASTLEN	BLEABBBB
E	kappa	Homo.sapiens	Hu_IGKV1-9*01	91.3	Hu_IGKV1-9*01	85.7	L3	9	L3-9-cis7-1	18	QQLNTYPFT	BBAABBbBB
E	kappa	Homo.sapiens	Hu_IGKV1-9*01	91.3	Hu_IGKV1-9*01	83.3	L4	6	L4-6-*	-1	GPGTEF	BBEABB
F	heavy	Homo.sapiens	Hu_IGHV4-39*03	79.2	Hu_IGHV4-39*03	100.0	H1	15	H1-15-*	-1	TVSGGSIssSSYYWG	BBABAELLBABABBB
F	heavy	Homo.sapiens	Hu_IGHV4-39*03	79.2	Hu_IGHV4-39*03	66.7	H2	9	H2-9-1	13	IIYFSGTTY	BBBAALBBB
F	heavy	Homo.sapiens	Hu_IGHV4-39*03	79.2	Hu_IGHV4-39*03	0.0	H3	20	H3-20-*	-1	AKPKSRdrggpgDDYFGMDV
F	heavy	Homo.sapiens	Hu_IGHV4-39*03	79.2	Hu_IGHV4-39*03	50.0	H4	8	H4-8-*	-1	LDRSTNRF	BALABBBB
G	heavy	Homo.sapiens	Hu_IGHV3-7*01	95.9	Hu_IGHV3-7*01	69.2	H1	13	H1-13-1	15	AASGFTFNKFWMN	BBBLBBAAABBBB
G	heavy	Homo.sapiens	Hu_IGHV3-7*01	95.9	Hu_IGHV3-7*01	60.0	H2	10	H2-10-2	10	DIQVDGSEKN	BBBAALABBB
G	heavy	Homo.sapiens	Hu_IGHV3-7*01	95.9	Hu_IGHV3-7*01	100.0	H3	14	H3-14-*	-1	ARGRYDYWSGYLSP	BBBABBLBAABBBb
G	heavy	Homo.sapiens	Hu_IGHV3-7*01	95.9	Hu_IGHV3-7*01	87.5	H4	8	H4-8-1	15	RDNGKNSL	BBAAALBB
H	kappa	Homo.sapiens	Hu_IGKV1-9*01	94.2	Hu_IGKV1-9*01	72.7	L1	11	L1-11-1	12	RASQGITTYLG	BBABBAEABBB
H	kappa	Homo.sapiens	Hu_IGKV1-9*01	94.2	Hu_IGKV1-9*01	87.5	L2	8	L2-8-1	8	YAASSLQS	BLLABBBB
H	kappa	Homo.sapiens	Hu_IGKV1-9*01	94.2	Hu_IGKV1-9*01	85.7	L3	9	L3-9-cis7-1	19	QQLNTYPYT	BBAABBbBB
H	kappa	Homo.sapiens	Hu_IGKV1-9*01	94.2	Hu_IGKV1-9*01	100.0	L4	6	L4-6-1	23	GSGTEF	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022