PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 5A7X

#CDRs = 8; #Clusters = 15.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
C	kappa	Homo.sapiens	Hu_IGKV3-15*01	95.7	Hu_IGKV3-15*01	81.8	L1	11	L1-11-1	23	RASESVSSDLA	BBBBBAEABBB
C	kappa	Homo.sapiens	Hu_IGKV3-15*01	95.7	Hu_IGKV3-15*01	100.0	L2	8	L2-8-1	17	YGASTRAT	BLEABBBB
C	kappa	Homo.sapiens	Hu_IGKV3-15*01	95.7	Hu_IGKV3-15*01	100.0	L3	11	L3-11-*	-1	QQYNNWPprYT	BBAABBbBBBB
C	kappa	Homo.sapiens	Hu_IGKV3-15*01	95.7	Hu_IGKV3-15*01	83.3	L4	6	L4-6-1	22	GSGAEF	EEEABB
D	heavy	Homo.sapiens	Hu_IGHV1-69*08	84.9	Hu_IGHV1-69*08	53.8	H1	13	H1-13-1	12	KASGDTFIRYSFT	BBBLBBAAABBBB
D	heavy	Homo.sapiens	Hu_IGHV1-69*08	84.9	Hu_IGHV1-69*08	60.0	H2	10	H2-10-1	25	RIITILDVAH	BBBAAALBBB
D	heavy	Homo.sapiens	Hu_IGHV1-69*08	84.9	Hu_IGHV1-69*08	50.0	H3	21	H3-21-*	-1	AgvyegeaDEGEYDNNGFLKH
D	heavy	Homo.sapiens	Hu_IGHV1-69*08	84.9	Hu_IGHV1-69*08	87.5	H4	8	H4-8-1	11	ADKSTSTV	BBAAALBB
G	kappa	Homo.sapiens	Hu_IGKV3-15*01	95.7	Hu_IGKV3-15*01	81.8	L1	11	L1-11-1	23	RASESVSSDLA	BBBBBAEABBB
G	kappa	Homo.sapiens	Hu_IGKV3-15*01	95.7	Hu_IGKV3-15*01	100.0	L2	8	L2-8-1	17	YGASTRAT	BLEABBBB
G	kappa	Homo.sapiens	Hu_IGKV3-15*01	95.7	Hu_IGKV3-15*01	100.0	L3	11	L3-11-*	-1	QQYNNWPprYT	BBAABBbBBBB
G	kappa	Homo.sapiens	Hu_IGKV3-15*01	95.7	Hu_IGKV3-15*01	83.3	L4	6	L4-6-1	22	GSGAEF	EEEABB
H	heavy	Homo.sapiens	Hu_IGHV1-69*08	84.9	Hu_IGHV1-69*08	53.8	H1	13	H1-13-1	13	KASGDTFIRYSFT	BBBLBBAAABBBB
H	heavy	Homo.sapiens	Hu_IGHV1-69*08	84.9	Hu_IGHV1-69*08	60.0	H2	10	H2-10-1	25	RIITILDVAH	BBBAAALBBB
H	heavy	Homo.sapiens	Hu_IGHV1-69*08	84.9	Hu_IGHV1-69*08	50.0	H3	21	H3-21-*	-1	AgvyegeaDEGEYDNNGFLKH
H	heavy	Homo.sapiens	Hu_IGHV1-69*08	84.9	Hu_IGHV1-69*08	87.5	H4	8	H4-8-1	11	ADKSTSTV	BBAAALBB
K	kappa	Homo.sapiens	Hu_IGKV3-15*01	95.7	Hu_IGKV3-15*01	81.8	L1	11	L1-11-1	23	RASESVSSDLA	BBBBBAEABBB
K	kappa	Homo.sapiens	Hu_IGKV3-15*01	95.7	Hu_IGKV3-15*01	100.0	L2	8	L2-8-1	17	YGASTRAT	BLEABBBB
K	kappa	Homo.sapiens	Hu_IGKV3-15*01	95.7	Hu_IGKV3-15*01	100.0	L3	11	L3-11-*	-1	QQYNNWPprYT	BBAABBbBBBB
K	kappa	Homo.sapiens	Hu_IGKV3-15*01	95.7	Hu_IGKV3-15*01	83.3	L4	6	L4-6-1	22	GSGAEF	EEEABB
L	heavy	Homo.sapiens	Hu_IGHV1-69*08	84.9	Hu_IGHV1-69*08	53.8	H1	13	H1-13-1	12	KASGDTFIRYSFT	BBBLBBAAABBBB
L	heavy	Homo.sapiens	Hu_IGHV1-69*08	84.9	Hu_IGHV1-69*08	60.0	H2	10	H2-10-1	25	RIITILDVAH	BBBAAALBBB
L	heavy	Homo.sapiens	Hu_IGHV1-69*08	84.9	Hu_IGHV1-69*08	50.0	H3	21	H3-21-*	-1	AgvyegeaDEGEYDNNGFLKH
L	heavy	Homo.sapiens	Hu_IGHV1-69*08	84.9	Hu_IGHV1-69*08	87.5	H4	8	H4-8-1	11	ADKSTSTV	BBAAALBB
M	kappa	Homo.sapiens	Hu_IGKV1-39*01	79.7	None	0.0	L1	12	L1-12-*	-1	RASQSITgNWVA	BBABBBAALBBB
M	kappa	Homo.sapiens	Hu_IGKV1-39*01	79.7	None	25.0	L2	8	L2-8-1	4	YRGAALLG	BLLABBBB
M	kappa	Homo.sapiens	Hu_IGKV1-39*01	79.7	Hu_IGKV1-39*01	42.9	L3	9	L3-9-cis7-1	7	QQYDTYPGT	BBAABBbBB
M	kappa	Homo.sapiens	Hu_IGKV1-39*01	79.7	Hu_IGKV1-39*01	66.7	L4	6	L4-6-2	9	AAGTDF	BBEABB
N	heavy	Homo.sapiens	Hu_IGHV1-18*02	77.8	None	-1.0	H1	14	H1-14-*	-1	KAYGVnTFGLYAVN	BBBLBABAAABBBB
N	heavy	Homo.sapiens	Hu_IGHV1-18*02	77.8	None	-1.0	H2	9	H2-9-*	-1	QIWRWKSSA
N	heavy	Homo.sapiens	Hu_IGHV1-18*02	77.8	Hu_IGHV1-18*02	0.0	H3	22	H3-22-*	-1	TTTSTYDKWSglhhdgvmAFSS
N	heavy	Homo.sapiens	Hu_IGHV1-18*02	77.8	Hu_IGHV1-18*02	0.0	H4	12	H4-12-*	-1	AVDltgsSPPIS
O	kappa	Homo.sapiens	Hu_IGKV1-39*01	79.7	None	0.0	L1	12	L1-12-*	-1	RASQSITgNWVA	BBABBBAALBBB
O	kappa	Homo.sapiens	Hu_IGKV1-39*01	79.7	None	25.0	L2	8	L2-8-1	4	YRGAALLG	BLLABBBB
O	kappa	Homo.sapiens	Hu_IGKV1-39*01	79.7	Hu_IGKV1-39*01	42.9	L3	9	L3-9-cis7-1	7	QQYDTYPGT	BBAABBbBB
O	kappa	Homo.sapiens	Hu_IGKV1-39*01	79.7	Hu_IGKV1-39*01	66.7	L4	6	L4-6-2	9	AAGTDF	BBEABB
P	heavy	Homo.sapiens	Hu_IGHV1-18*02	77.8	None	-1.0	H1	14	H1-14-*	-1	KAYGVnTFGLYAVN	BBBLBABAAABBBB
P	heavy	Homo.sapiens	Hu_IGHV1-18*02	77.8	None	-1.0	H2	9	H2-9-*	-1	QIWRWKSSA
P	heavy	Homo.sapiens	Hu_IGHV1-18*02	77.8	Hu_IGHV1-18*02	0.0	H3	22	H3-22-*	-1	TTTSTYDKWSglhhdgvmAFSS
P	heavy	Homo.sapiens	Hu_IGHV1-18*02	77.8	Hu_IGHV1-18*02	0.0	H4	12	H4-12-*	-1	AVDltgsSPPIS
Q	kappa	Homo.sapiens	Hu_IGKV1-39*01	79.7	None	0.0	L1	12	L1-12-*	-1	RASQSITgNWVA	BBABBBAALBBB
Q	kappa	Homo.sapiens	Hu_IGKV1-39*01	79.7	None	25.0	L2	8	L2-8-1	4	YRGAALLG	BLLABBBB
Q	kappa	Homo.sapiens	Hu_IGKV1-39*01	79.7	Hu_IGKV1-39*01	42.9	L3	9	L3-9-cis7-1	7	QQYDTYPGT	BBAABBbBB
Q	kappa	Homo.sapiens	Hu_IGKV1-39*01	79.7	Hu_IGKV1-39*01	66.7	L4	6	L4-6-2	9	AAGTDF	BBEABB
R	heavy	Homo.sapiens	Hu_IGHV1-18*02	77.8	None	-1.0	H1	14	H1-14-*	-1	KAYGVnTFGLYAVN	BBBLBABAAABBBB
R	heavy	Homo.sapiens	Hu_IGHV1-18*02	77.8	None	-1.0	H2	9	H2-9-*	-1	QIWRWKSSA
R	heavy	Homo.sapiens	Hu_IGHV1-18*02	77.8	Hu_IGHV1-18*02	0.0	H3	22	H3-22-*	-1	TTTSTYDKWSglhhdgvmAFSS
R	heavy	Homo.sapiens	Hu_IGHV1-18*02	77.8	Hu_IGHV1-18*02	0.0	H4	12	H4-12-*	-1	AVDltgsSPPIS

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022