PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 4YGV

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	heavy	Homo.sapiens	Hu_IGHV1-46*01	91.8	Hu_IGHV1-46*01	92.3	H1	13	H1-13-1	10	KASGYTFTDYYMH	BBBLBBAAABBBB
A	heavy	Homo.sapiens	Hu_IGHV1-46*01	91.8	Hu_IGHV1-46*01	40.0	H2	10	H2-10-1	8	ETNPRNGGTT	BBBAAALBBB
A	heavy	Homo.sapiens	Hu_IGHV1-46*01	91.8	Hu_IGHV1-46*01	0.0	H3	12	H3-12-*	-1	TIGTSGYDYFDY	BBBAALBABBAB
A	heavy	Homo.sapiens	Hu_IGHV1-46*01	91.8	Hu_IGHV1-46*01	87.5	H4	8	H4-8-1	7	RDTSTSTA	BBAAALBB
B	kappa	Homo.sapiens	Hu_IGKV2-29*02	98.6	Hu_IGKV2-29*02	62.5	L1	16	L1-16-1	10	RSSQSIvhsdgNIYLE	BBABBABBAALBBBBB
B	kappa	Homo.sapiens	Hu_IGKV2-29*02	98.6	Hu_IGKV2-29*02	75.0	L2	8	L2-8-1	6	YKVSYRFS	BLEABBBB
B	kappa	Homo.sapiens	Hu_IGKV2-29*02	98.6	Hu_IGKV2-29*02	42.9	L3	9	L3-9-cis7-1	6	FQASHVPYT	BBAABBbBB
B	kappa	Homo.sapiens	Hu_IGKV2-29*02	98.6	Hu_IGKV2-29*02	100.0	L4	6	L4-6-1	9	GSGTDF	EBEABB
F	heavy	Homo.sapiens	Hu_IGHV1-46*01	91.8	Hu_IGHV1-46*01	92.3	H1	13	H1-13-1	10	KASGYTFTDYYMH	BBBLBBAAABBBB
F	heavy	Homo.sapiens	Hu_IGHV1-46*01	91.8	Hu_IGHV1-46*01	40.0	H2	10	H2-10-1	8	ETNPRNGGTT	BBBAAALBBB
F	heavy	Homo.sapiens	Hu_IGHV1-46*01	91.8	Hu_IGHV1-46*01	0.0	H3	12	H3-12-*	-1	TIGTSGYDYFDY	BBBAALBABBAB
F	heavy	Homo.sapiens	Hu_IGHV1-46*01	91.8	Hu_IGHV1-46*01	87.5	H4	8	H4-8-1	7	RDTSTSTA	BBAAALBB
L	kappa	Homo.sapiens	Hu_IGKV2-29*02	98.6	Hu_IGKV2-29*02	62.5	L1	16	L1-16-1	12	RSSQSIvhsdgNIYLE	BBABBABBAALBBBBB
L	kappa	Homo.sapiens	Hu_IGKV2-29*02	98.6	Hu_IGKV2-29*02	75.0	L2	8	L2-8-1	4	YKVSYRFS	BLEABBBB
L	kappa	Homo.sapiens	Hu_IGKV2-29*02	98.6	Hu_IGKV2-29*02	42.9	L3	9	L3-9-cis7-1	8	FQASHVPYT	BBAABBbBB
L	kappa	Homo.sapiens	Hu_IGKV2-29*02	98.6	Hu_IGKV2-29*02	100.0	L4	6	L4-6-1	8	GSGTDF	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022