PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 4YC2

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
B	heavy	Homo.sapiens	Hu_IGHV4-31*02	89.0	Hu_IGHV4-31*02	80.0	H1	15	H1-15-*	-1	TVSGgSSSSgaHYWS
B	heavy	Homo.sapiens	Hu_IGHV4-31*02	89.0	Hu_IGHV4-31*02	77.8	H2	9	H2-9-1	13	YIHYSGNTY	BBBAALBBB
B	heavy	Homo.sapiens	Hu_IGHV4-31*02	89.0	Hu_IGHV4-31*02	100.0	H3	15	H3-15-*	-1	ARGTRLrTLRNAFDI
B	heavy	Homo.sapiens	Hu_IGHV4-31*02	89.0	Hu_IGHV4-31*02	62.5	H4	8	H4-8-1	22	QHTSENQF	BBAAALBB
C	lambda	Homo.sapiens	Hu_IGLV2-8*01	93.9	Hu_IGLV2-8*01	100.0	L1	14	L1-14-*	-1	TGTSSDVGgYNYVS	BBBAABBLABBABB
C	lambda	Homo.sapiens	Hu_IGLV2-8*01	93.9	Hu_IGLV2-8*01	62.5	L2	8	L2-8-1	14	SEVNNRPS	BLLABBBB
C	lambda	Homo.sapiens	Hu_IGLV2-8*01	93.9	Hu_IGLV2-8*01	55.6	L3	10	L3-10-*	-1	SSYTDIHNFV	BBBBELLBBB
C	lambda	Homo.sapiens	Hu_IGLV2-8*01	93.9	Hu_IGLV2-8*01	100.0	L4	6	L4-6-*	-1	KSGNTA	BABABB
H	heavy	Homo.sapiens	Hu_IGHV4-31*02	89.0	Hu_IGHV4-31*02	80.0	H1	15	H1-15-*	-1	TVSGGSSSSgaHYWS	BBBAeAEAABBBBBB
H	heavy	Homo.sapiens	Hu_IGHV4-31*02	89.0	Hu_IGHV4-31*02	77.8	H2	9	H2-9-1	15	YIHYSGNTY	BBBAALBBB
H	heavy	Homo.sapiens	Hu_IGHV4-31*02	89.0	Hu_IGHV4-31*02	100.0	H3	15	H3-15-*	-1	ARGTRLrTLRNAFDI
H	heavy	Homo.sapiens	Hu_IGHV4-31*02	89.0	Hu_IGHV4-31*02	62.5	H4	8	H4-8-1	20	QHTSENQF	BBAAALBB
L	lambda	Homo.sapiens	Hu_IGLV2-8*01	93.9	Hu_IGLV2-8*01	100.0	L1	14	L1-14-*	-1	TGTSSDVGgYNYVS	BBBAAABLABBABB
L	lambda	Homo.sapiens	Hu_IGLV2-8*01	93.9	Hu_IGLV2-8*01	62.5	L2	8	L2-8-1	17	SEVNNRPS	BLEABBBB
L	lambda	Homo.sapiens	Hu_IGLV2-8*01	93.9	Hu_IGLV2-8*01	55.6	L3	10	L3-10-*	-1	SSYTDIHNFV	BBBBEBLBBB
L	lambda	Homo.sapiens	Hu_IGLV2-8*01	93.9	Hu_IGLV2-8*01	100.0	L4	6	L4-6-*	-1	KSGNTA	BAAABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022