PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 4XX1

#CDRs = 8; #Clusters = 11.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
E	heavy	Homo.sapiens	Hu_IGHV3-33*01	97.3	Hu_IGHV3-33*01	100.0	H1	13	H1-13-1	10	AASGFTFSSYGMH	BBBLBBAAABBBB
E	heavy	Homo.sapiens	Hu_IGHV3-33*01	97.3	Hu_IGHV3-33*01	90.0	H2	10	H2-10-2	17	VIWYDGSNKF	BBBAALABBB
E	heavy	Homo.sapiens	Hu_IGHV3-33*01	97.3	Hu_IGHV3-33*01	100.0	H3	19	H3-19-*	-1	AREGAavrsfYYSYYGMDV
E	heavy	Homo.sapiens	Hu_IGHV3-33*01	97.3	Hu_IGHV3-33*01	100.0	H4	8	H4-8-1	18	RDNSKNTL	BBAAALBB
G	lambda	Homo.sapiens	Hu_IGLV3-1*01	97.0	Hu_IGLV3-1*01	63.6	L1	11	L1-11-3	17	SGDKLGNKFTS	BBBLAAABBBB
G	lambda	Homo.sapiens	Hu_IGLV3-1*01	97.0	Hu_IGLV3-1*01	87.5	L2	8	L2-8-1	16	YQDTKRPS	BLLABBBB
G	lambda	Homo.sapiens	Hu_IGLV3-1*01	97.0	Hu_IGLV3-1*01	100.0	L3	10	L3-10-*	-1	QAWDSSTAWV	BBBBAABBLB
G	lambda	Homo.sapiens	Hu_IGLV3-1*01	97.0	Hu_IGLV3-1*01	83.3	L4	6	L4-6-2	13	TSGNTA	BBEABB
H	heavy	Homo.sapiens	Hu_IGHV3-33*01	97.3	Hu_IGHV3-33*01	100.0	H1	13	H1-13-1	13	AASGFTFSSYGMH	BBBLBBAAABBBB
H	heavy	Homo.sapiens	Hu_IGHV3-33*01	97.3	Hu_IGHV3-33*01	90.0	H2	10	H2-10-2	19	VIWYDGSNKF	BBBAALABBB
H	heavy	Homo.sapiens	Hu_IGHV3-33*01	97.3	Hu_IGHV3-33*01	100.0	H3	19	H3-19-*	-1	AREGAavrsfYYSYYGMDV
H	heavy	Homo.sapiens	Hu_IGHV3-33*01	97.3	Hu_IGHV3-33*01	100.0	H4	8	H4-8-1	12	RDNSKNTL	BBAAALBB
L	lambda	Homo.sapiens	Hu_IGLV3-1*01	97.0	Hu_IGLV3-1*01	63.6	L1	11	L1-11-3	15	SGDKLGNKFTS	BEBLAAABBBB
L	lambda	Homo.sapiens	Hu_IGLV3-1*01	97.0	Hu_IGLV3-1*01	87.5	L2	8	L2-8-1	18	YQDTKRPS	BLEABBBB
L	lambda	Homo.sapiens	Hu_IGLV3-1*01	97.0	Hu_IGLV3-1*01	100.0	L3	10	L3-10-*	-1	QAWDSSTAWV	BBBBAABBLB
L	lambda	Homo.sapiens	Hu_IGLV3-1*01	97.0	Hu_IGLV3-1*01	83.3	L4	6	L4-6-2	16	TSGNTA	BBEABB
M	heavy	Homo.sapiens	Hu_IGHV3-33*01	97.3	Hu_IGHV3-33*01	100.0	H1	13	H1-13-1	20	AASGFTFSSYGMH	BBBLBBAAABBBB
M	heavy	Homo.sapiens	Hu_IGHV3-33*01	97.3	Hu_IGHV3-33*01	90.0	H2	10	H2-10-2	32	VIWYDGSNKF	BBBAALABBB
M	heavy	Homo.sapiens	Hu_IGHV3-33*01	97.3	Hu_IGHV3-33*01	100.0	H3	19	H3-19-*	-1	AREGAavrsfYYSYYGMDV
M	heavy	Homo.sapiens	Hu_IGHV3-33*01	97.3	Hu_IGHV3-33*01	100.0	H4	8	H4-8-*	-1	RDNSKNTL	BBAABLBB
O	lambda	Homo.sapiens	Hu_IGLV3-1*01	97.0	Hu_IGLV3-1*01	63.6	L1	11	L1-11-*	-1	SGDKLGNKFTS	BEBLAAABBBB
O	lambda	Homo.sapiens	Hu_IGLV3-1*01	97.0	Hu_IGLV3-1*01	87.5	L2	8	L2-8-*	-1	YQDTKRPS	BLLABEBB
O	lambda	Homo.sapiens	Hu_IGLV3-1*01	97.0	Hu_IGLV3-1*01	100.0	L3	10	L3-10-*	-1	QAWDSSTAWV	BBBBAABBLB
O	lambda	Homo.sapiens	Hu_IGLV3-1*01	97.0	Hu_IGLV3-1*01	83.3	L4	6	L4-6-2	24	TSGNTA	BBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022