PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 4XNQ

#CDRs = 8; #Clusters = 9.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	lambda	Homo.sapiens	Hu_IGLV3-1*01	93.9	Hu_IGLV3-1*01	81.8	L1	11	L1-11-3	8	SGDTLGDKYVC	BBBLAAABBBB
A	lambda	Homo.sapiens	Hu_IGLV3-1*01	93.9	Hu_IGLV3-1*01	87.5	L2	8	L2-8-1	8	YQDTKRPS	BLLABBBB
A	lambda	Homo.sapiens	Hu_IGLV3-1*01	93.9	Hu_IGLV3-1*01	75.0	L3	9	L3-9-4	17	QAWDSSSFV	BBBBLABBB
A	lambda	Homo.sapiens	Hu_IGLV3-1*01	93.9	Hu_IGLV3-1*01	83.3	L4	6	L4-6-2	13	NSGDTA	BBEABB
B	heavy	Homo.sapiens	Hu_IGHV4-4*02	97.3	Hu_IGHV4-4*02	92.9	H1	14	H1-14-*	-1	AVSGGSISsSYWWS	BBBLBBABBABBBB
B	heavy	Homo.sapiens	Hu_IGHV4-4*02	97.3	Hu_IGHV4-4*02	88.9	H2	9	H2-9-1	11	EIYHSGNTN	BBBAALBBB
B	heavy	Homo.sapiens	Hu_IGHV4-4*02	97.3	Hu_IGHV4-4*02	100.0	H3	16	H3-16-*	-1	ARVALFDilTGGWFDP
B	heavy	Homo.sapiens	Hu_IGHV4-4*02	97.3	Hu_IGHV4-4*02	87.5	H4	8	H4-8-1	11	VDKSKNLF	BBAAALBB
H	heavy	Homo.sapiens	Hu_IGHV4-4*02	97.3	Hu_IGHV4-4*02	92.9	H1	14	H1-14-*	-1	AVSGGSISsSYWWS	BBBLBBABBABBBB
H	heavy	Homo.sapiens	Hu_IGHV4-4*02	97.3	Hu_IGHV4-4*02	88.9	H2	9	H2-9-1	11	EIYHSGNTN	BBBAALBBB
H	heavy	Homo.sapiens	Hu_IGHV4-4*02	97.3	Hu_IGHV4-4*02	100.0	H3	16	H3-16-*	-1	ARVALFDilTGGWFDP
H	heavy	Homo.sapiens	Hu_IGHV4-4*02	97.3	Hu_IGHV4-4*02	87.5	H4	8	H4-8-1	11	VDKSKNLF	BBAAALBB
L	lambda	Homo.sapiens	Hu_IGLV3-1*01	93.9	Hu_IGLV3-1*01	81.8	L1	11	L1-11-3	8	SGDTLGDKYVC	BBBLAAABBBB
L	lambda	Homo.sapiens	Hu_IGLV3-1*01	93.9	Hu_IGLV3-1*01	87.5	L2	8	L2-8-1	7	YQDTKRPS	BLLABBBB
L	lambda	Homo.sapiens	Hu_IGLV3-1*01	93.9	Hu_IGLV3-1*01	75.0	L3	9	L3-9-1	12	QAWDSSSFV	BBBBLLBBB
L	lambda	Homo.sapiens	Hu_IGLV3-1*01	93.9	Hu_IGLV3-1*01	83.3	L4	6	L4-6-2	12	NSGDTA	BBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022