PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 4XGZ

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Ca_IGHV1S29*01	53.8	H1	13	H1-13-1	13	AASGFNVSYSSIH	BBBLBBAAABBBB
A	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Ca_IGHV1S29*01	50.0	H2	10	H2-10-1	11	SIYSYYGYTY	BBBAAALBBB
A	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	100.0	H3	11	H3-11-*	-1	ARGYYGAAMDY	BBBBBLLBBAB
A	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	62.5	H4	8	H4-8-1	8	ADTSKNTA	BBAAALBB
B	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Ca_IGKV1-26*01	63.6	L1	11	L1-11-*	-1	RASQSVSSAVA	BALBBAABBBB
B	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Ca_IGKV1-26*01	75.0	L2	8	L2-8-1	5	YSASSLYS	BLEABBBB
B	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	57.1	L3	9	L3-9-3	15	QQSSSSLIT	BBBBAABBB
B	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	83.3	L4	6	L4-6-2	13	RSGTDF	BBEABB
C	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Ca_IGHV1S29*01	53.8	H1	13	H1-13-1	13	AASGFNVSYSSIH	BBBLBBAAABBBB
C	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Ca_IGHV1S29*01	50.0	H2	10	H2-10-1	12	SIYSYYGYTY	BBBAAALBBB
C	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	100.0	H3	11	H3-11-*	-1	ARGYYGAAMDY	BBBBBLLBBAB
C	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	62.5	H4	8	H4-8-1	8	ADTSKNTA	BBAAALBB
D	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Ca_IGKV1-26*01	63.6	L1	11	L1-11-*	-1	RASQSVSSAVA	BALBBAABBBB
D	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Ca_IGKV1-26*01	75.0	L2	8	L2-8-1	5	YSASSLYS	BLEABBBB
D	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	57.1	L3	9	L3-9-3	15	QQSSSSLIT	BBBBAABBB
D	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	83.3	L4	6	L4-6-2	13	RSGTDF	BBEABB
E	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Ca_IGHV1S29*01	53.8	H1	13	H1-13-1	13	AASGFNVSYSSIH	BBBLBBAAABBBB
E	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Ca_IGHV1S29*01	50.0	H2	10	H2-10-1	11	SIYSYYGYTY	BBBAAALBBB
E	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	100.0	H3	11	H3-11-*	-1	ARGYYGAAMDY	BBBBBLLBBAB
E	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	62.5	H4	8	H4-8-1	8	ADTSKNTA	BBAAALBB
F	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Ca_IGKV1-26*01	63.6	L1	11	L1-11-*	-1	RASQSVSSAVA	BALBBAABBBB
F	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Ca_IGKV1-26*01	75.0	L2	8	L2-8-1	5	YSASSLYS	BLEABBBB
F	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	57.1	L3	9	L3-9-3	15	QQSSSSLIT	BBBBAABBB
F	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	83.3	L4	6	L4-6-2	13	RSGTDF	BBEABB
G	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Ca_IGHV1S29*01	53.8	H1	13	H1-13-1	13	AASGFNVSYSSIH	BBBLBBAAABBBB
G	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Ca_IGHV1S29*01	50.0	H2	10	H2-10-1	12	SIYSYYGYTY	BBBAAALBBB
G	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	100.0	H3	11	H3-11-*	-1	ARGYYGAAMDY	BBBBBLLBBAB
G	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	62.5	H4	8	H4-8-1	8	ADTSKNTA	BBAAALBB
H	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Ca_IGHV1S29*01	53.8	H1	13	H1-13-1	13	AASGFNVSYSSIH	BBBLBBAAABBBB
H	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Ca_IGHV1S29*01	50.0	H2	10	H2-10-1	11	SIYSYYGYTY	BBBAAALBBB
H	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	100.0	H3	11	H3-11-*	-1	ARGYYGAAMDY	BBBBBLLBBAB
H	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	62.5	H4	8	H4-8-1	8	ADTSKNTA	BBAAALBB
I	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Ca_IGKV1-26*01	63.6	L1	11	L1-11-*	-1	RASQSVSSAVA	BALBBAABBBB
I	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Ca_IGKV1-26*01	75.0	L2	8	L2-8-1	5	YSASSLYS	BLEABBBB
I	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	57.1	L3	9	L3-9-3	15	QQSSSSLIT	BBBBAABBB
I	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	83.3	L4	6	L4-6-2	13	RSGTDF	BBEABB
J	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Ca_IGHV1S29*01	53.8	H1	13	H1-13-1	13	AASGFNVSYSSIH	BBBLBBAAABBBB
J	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Ca_IGHV1S29*01	50.0	H2	10	H2-10-1	11	SIYSYYGYTY	BBBAAALBBB
J	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	100.0	H3	11	H3-11-*	-1	ARGYYGAAMDY	BBBBBLLBBAB
J	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	62.5	H4	8	H4-8-1	8	ADTSKNTA	BBAAALBB
K	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Ca_IGKV1-26*01	63.6	L1	11	L1-11-*	-1	RASQSVSSAVA	BALBBAABBBB
K	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Ca_IGKV1-26*01	75.0	L2	8	L2-8-1	5	YSASSLYS	BLEABBBB
K	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	57.1	L3	9	L3-9-3	15	QQSSSSLIT	BBBBAABBB
K	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	83.3	L4	6	L4-6-2	13	RSGTDF	BBEABB
L	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Ca_IGKV1-26*01	63.6	L1	11	L1-11-*	-1	RASQSVSSAVA	BALBBAABBBB
L	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Ca_IGKV1-26*01	75.0	L2	8	L2-8-1	5	YSASSLYS	BLEABBBB
L	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	57.1	L3	9	L3-9-3	15	QQSSSSLIT	BBBBAABBB
L	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	83.3	L4	6	L4-6-2	13	RSGTDF	BBEABB
M	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Ca_IGHV1S29*01	53.8	H1	13	H1-13-1	13	AASGFNVSYSSIH	BBBLBBAAABBBB
M	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Ca_IGHV1S29*01	50.0	H2	10	H2-10-1	11	SIYSYYGYTY	BBBAAALBBB
M	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	100.0	H3	11	H3-11-*	-1	ARGYYGAAMDY	BBBBBLLBBAB
M	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	62.5	H4	8	H4-8-1	8	ADTSKNTA	BBAAALBB
N	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Ca_IGKV1-26*01	63.6	L1	11	L1-11-*	-1	RASQSVSSAVA	BALBBAALBBB
N	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Ca_IGKV1-26*01	75.0	L2	8	L2-8-1	5	YSASSLYS	BLEABBBB
N	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	57.1	L3	9	L3-9-3	15	QQSSSSLIT	BBBBAABBB
N	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	83.3	L4	6	L4-6-2	13	RSGTDF	BBEABB
O	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Ca_IGHV1S29*01	53.8	H1	13	H1-13-1	13	AASGFNVSYSSIH	BBBLBBAAABBBB
O	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Ca_IGHV1S29*01	50.0	H2	10	H2-10-1	11	SIYSYYGYTY	BBBAAALBBB
O	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	100.0	H3	11	H3-11-*	-1	ARGYYGAAMDY	BBBBBLLBBAB
O	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	62.5	H4	8	H4-8-1	8	ADTSKNTA	BBAAALBB
P	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Ca_IGKV1-26*01	63.6	L1	11	L1-11-*	-1	RASQSVSSAVA	BALBBAABBBB
P	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Ca_IGKV1-26*01	75.0	L2	8	L2-8-1	5	YSASSLYS	BLEABBBB
P	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	57.1	L3	9	L3-9-3	15	QQSSSSLIT	BBBBAABBB
P	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	83.3	L4	6	L4-6-2	13	RSGTDF	BBEABB
Q	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Ca_IGHV1S29*01	53.8	H1	13	H1-13-1	13	AASGFNVSYSSIH	BBBLBBAAABBBB
Q	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Ca_IGHV1S29*01	50.0	H2	10	H2-10-1	12	SIYSYYGYTY	BBBAAALBBB
Q	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	100.0	H3	11	H3-11-*	-1	ARGYYGAAMDY	BBBBBLLBBAB
Q	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	62.5	H4	8	H4-8-1	8	ADTSKNTA	BBAAALBB
R	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Ca_IGKV1-26*01	63.6	L1	11	L1-11-*	-1	RASQSVSSAVA	BALBBAABBBB
R	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Ca_IGKV1-26*01	75.0	L2	8	L2-8-1	5	YSASSLYS	BLEABBBB
R	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	57.1	L3	9	L3-9-3	15	QQSSSSLIT	BBBBAABBB
R	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	83.3	L4	6	L4-6-2	13	RSGTDF	BBEABB
S	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Ca_IGHV1S29*01	53.8	H1	13	H1-13-1	13	AASGFNVSYSSIH	BBBLBBAAABBBB
S	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Ca_IGHV1S29*01	50.0	H2	10	H2-10-1	11	SIYSYYGYTY	BBBAAALBBB
S	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	100.0	H3	11	H3-11-*	-1	ARGYYGAAMDY	BBBBBLLBBAB
S	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	62.5	H4	8	H4-8-1	8	ADTSKNTA	BBAAALBB
T	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Ca_IGKV1-26*01	63.6	L1	11	L1-11-*	-1	RASQSVSSAVA	BALBBAABBBB
T	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Ca_IGKV1-26*01	75.0	L2	8	L2-8-1	5	YSASSLYS	BLEABBBB
T	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	57.1	L3	9	L3-9-3	15	QQSSSSLIT	BBBBAABBB
T	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	83.3	L4	6	L4-6-2	13	RSGTDF	BBEABB
U	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Ca_IGHV1S29*01	53.8	H1	13	H1-13-1	13	AASGFNVSYSSIH	BBBLBBAAABBBB
U	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Ca_IGHV1S29*01	50.0	H2	10	H2-10-1	11	SIYSYYGYTY	BBBAAALBBB
U	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	100.0	H3	11	H3-11-*	-1	ARGYYGAAMDY	BBBBBLLBBAB
U	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	62.5	H4	8	H4-8-1	8	ADTSKNTA	BBAAALBB
V	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Ca_IGKV1-26*01	63.6	L1	11	L1-11-*	-1	RASQSVSSAVA	BALBBAABBBB
V	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Ca_IGKV1-26*01	75.0	L2	8	L2-8-1	5	YSASSLYS	BLEABBBB
V	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	57.1	L3	9	L3-9-3	15	QQSSSSLIT	BBBBAABBB
V	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	83.3	L4	6	L4-6-2	13	RSGTDF	BBEABB
W	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Ca_IGHV1S29*01	53.8	H1	13	H1-13-1	13	AASGFNVSYSSIH	BBBLBBAAABBBB
W	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Ca_IGHV1S29*01	50.0	H2	10	H2-10-1	12	SIYSYYGYTY	BBBAAALBBB
W	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	100.0	H3	11	H3-11-*	-1	ARGYYGAAMDY	BBBBBLLBBAB
W	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	62.5	H4	8	H4-8-1	8	ADTSKNTA	BBAAALBB
X	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Ca_IGKV1-26*01	63.6	L1	11	L1-11-*	-1	RASQSVSSAVA	BALBBAABBBB
X	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Ca_IGKV1-26*01	75.0	L2	8	L2-8-1	5	YSASSLYS	BLEABBBB
X	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	57.1	L3	9	L3-9-3	15	QQSSSSLIT	BBBBAABBB
X	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	83.3	L4	6	L4-6-2	13	RSGTDF	BBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022