PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 4WV1

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Mo_IGKV6-15*01	54.5	L1	11	L1-11-1	6	RASQDVDTSLA	BBABBAEABBB
A	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Mo_IGKV6-15*01	75.0	L2	8	L2-8-1	4	YSASFLYS	BLLABBBB
A	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	57.1	L3	9	L3-9-*	-1	QQSTGHPQT	BBBBABBBB
A	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	100.0	L4	6	L4-6-1	8	GSGTDF	EBEABB
B	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Mo_IGHV1-55*04	61.5	H1	13	H1-13-*	-1	AASGFTFTSTGIS	BBBLBBAAABBBB
B	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Mo_IGHV1-55*04	70.0	H2	10	H2-10-1	13	RTHLGDGSTN	BBBAAALBBB
B	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	100.0	H3	20	H3-20-*	-1	ARTYGiydlyvDYTEYVMDY
B	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	62.5	H4	8	H4-8-1	8	ADTSKNTA	BBAAALBB
D	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Mo_IGKV6-15*01	54.5	L1	11	L1-11-1	6	RASQDVDTSLA	BBABBAEABBB
D	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Mo_IGKV6-15*01	75.0	L2	8	L2-8-1	4	YSASFLYS	BLLABBBB
D	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	57.1	L3	9	L3-9-*	-1	QQSTGHPQT	BBBBABBBB
D	kappa	Homo.sapiens	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	100.0	L4	6	L4-6-1	8	GSGTDF	EBEABB
E	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Mo_IGHV1-55*04	61.5	H1	13	H1-13-*	-1	AASGFTFTSTGIS	BBBLBBAAABBBB
E	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Mo_IGHV1-55*04	70.0	H2	10	H2-10-1	13	RTHLGDGSTN	BBBAAALBBB
E	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	100.0	H3	20	H3-20-*	-1	ARTYGiydlyvDYTEYVMDY
E	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	62.5	H4	8	H4-8-1	8	ADTSKNTA	BBAAALBB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022