PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 4S1R

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
H	heavy	Homo.sapiens	Hu_IGHV1-2*07	67.1	Hu_IGHV1-2*07	30.8	H1	13	H1-13-1	12	GTSGYDFMESLIN	BBBLBBAAABBBB
H	heavy	Homo.sapiens	Hu_IGHV1-2*07	67.1	Hu_IGHV1-2*07	70.0	H2	10	H2-10-1	15	WINPRGGGVN	BBBAAALBBB
H	heavy	Homo.sapiens	Hu_IGHV1-2*07	67.1	Hu_IGHV1-2*07	50.0	H3	25	H3-25-*	-1	VRGKSCcggrrycngadCFNWDFEH
H	heavy	Homo.sapiens	Hu_IGHV1-2*07	67.1	Hu_IGHV1-2*07	62.5	H4	8	H4-8-1	12	RDVSSGTA	BBAAALBB
L	kappa	Homo.sapiens	Hu_IGKV3-20*01	81.2	CDRLenMismatch	-1.0	L1	9	L1-9-*	-1	RTSQYGSLA
L	kappa	Homo.sapiens	Hu_IGKV3-20*01	81.2	Hu_IGKV3-20*01	50.0	L2	8	L2-8-1	12	YSGSTRAA	BLEABBBB
L	kappa	Homo.sapiens	Hu_IGKV3-20*01	81.2	Hu_IGKV3-20*01	0.0	L3	5	L3-5-1	13	QQYEF	BBEAB
L	kappa	Homo.sapiens	Hu_IGKV3-20*01	81.2	Hu_IGKV3-20*01	33.3	L4	6	L4-6-2	23	RWGPDY	BBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022