PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 4S1Q

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
H	heavy	Homo.sapiens	Hu_IGHV1-18*02	68.9	Hu_IGHV1-18*02	53.8	H1	13	H1-13-1	15	RASGYNFREYSIH	BBBLBBAAABBBB
H	heavy	Homo.sapiens	Hu_IGHV1-18*02	68.9	Hu_IGHV1-18*02	30.0	H2	10	H2-10-1	11	WIKGMWGAVS	BBBAAALBBB
H	heavy	Homo.sapiens	Hu_IGHV1-18*02	68.9	Hu_IGHV1-18*02	0.0	H3	17	H3-17-*	-1	VRKGPScphCGDFHWQH
H	heavy	Homo.sapiens	Hu_IGHV1-18*02	68.9	Hu_IGHV1-18*02	0.0	H4	15	H4-15-*	-1	RQLSQDpddpdwgIA
L	kappa	Homo.sapiens	Hu_IGKV3-20*01	81.2	CDRLenMismatch	-1.0	L1	9	L1-9-*	-1	RTSQYGSLA
L	kappa	Homo.sapiens	Hu_IGKV3-20*01	81.2	Hu_IGKV3-20*01	50.0	L2	8	L2-8-1	12	YSGSTRAA	BLEABBBB
L	kappa	Homo.sapiens	Hu_IGKV3-20*01	81.2	Hu_IGKV3-20*01	0.0	L3	5	L3-5-1	6	QQYEF	BBEAB
L	kappa	Homo.sapiens	Hu_IGKV3-20*01	81.2	Hu_IGKV3-20*01	33.3	L4	6	L4-6-*	-1	RWGPDY	ABEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022