PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 4RZC

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	heavy	Oryctolagus.cuniculus	Rb_IGHV1S40*01	92.8	CDRLenMismatch	-1.0	H1	13	H1-13-1	20	KASGFDFTWYTMN	BBBLBBAAABBBB
A	heavy	Oryctolagus.cuniculus	Rb_IGHV1S40*01	92.8	Rb_IGHV1S40*01	54.5	H2	11	H2-11-*	-1	SIGAGvYGSNY	BBBBEAABBBB
A	heavy	Oryctolagus.cuniculus	Rb_IGHV1S40*01	92.8	Rb_IGHV1S40*01	100.0	H3	11	H3-11-*	-1	ARDGINGGYDI	BBBABLLBBAB
A	heavy	Oryctolagus.cuniculus	Rb_IGHV1S40*01	92.8	Rb_IGHV1S40*01	85.7	H4	7	H4-7-1	15	KASSTTV	BABAABB
B	kappa	Oryctolagus.cuniculus	Rb_IGKV1S45*01	83.6	CDRLenMismatch	-1.0	L1	12	L1-12-*	-1	QSSQSVyNNRLA	BBABBBBEABBB
B	kappa	Oryctolagus.cuniculus	Rb_IGKV1S45*01	83.6	Rb_IGKV1S45*01	100.0	L2	8	L2-8-1	9	YSASTLAS	BLLABBBB
B	kappa	Oryctolagus.cuniculus	Rb_IGKV1S45*01	83.6	Rb_IGKV1S45*01	0.0	L3	12	L3-12-*	-1	HggyRSndDRYA
B	kappa	Oryctolagus.cuniculus	Rb_IGKV1S45*01	83.6	Rb_IGKV1S45*01	100.0	L4	6	L4-6-*	-1	GSGTQF	EBEeBB
C	heavy	Oryctolagus.cuniculus	Rb_IGHV1S40*01	92.8	CDRLenMismatch	-1.0	H1	13	H1-13-1	20	KASGFDFTWYTMN	BBBLBBAAABBBB
C	heavy	Oryctolagus.cuniculus	Rb_IGHV1S40*01	92.8	Rb_IGHV1S40*01	54.5	H2	11	H2-11-*	-1	SIGAGvYGSNY	BBBBEAABBBB
C	heavy	Oryctolagus.cuniculus	Rb_IGHV1S40*01	92.8	Rb_IGHV1S40*01	100.0	H3	11	H3-11-*	-1	ARDGINGGYDI	BBBABLLBBAB
C	heavy	Oryctolagus.cuniculus	Rb_IGHV1S40*01	92.8	Rb_IGHV1S40*01	85.7	H4	7	H4-7-1	14	KASSTTV	BABAABB
D	kappa	Oryctolagus.cuniculus	Rb_IGKV1S45*01	83.6	CDRLenMismatch	-1.0	L1	12	L1-12-*	-1	QSSQSVyNNRLA	BBABBBBEABBB
D	kappa	Oryctolagus.cuniculus	Rb_IGKV1S45*01	83.6	Rb_IGKV1S45*01	100.0	L2	8	L2-8-1	9	YSASTLAS	BLLABBBB
D	kappa	Oryctolagus.cuniculus	Rb_IGKV1S45*01	83.6	Rb_IGKV1S45*01	0.0	L3	12	L3-12-*	-1	HggyRSNDDRYA
D	kappa	Oryctolagus.cuniculus	Rb_IGKV1S45*01	83.6	Rb_IGKV1S45*01	100.0	L4	6	L4-6-*	-1	GSGTQF	EBEeBB
E	heavy	Oryctolagus.cuniculus	Rb_IGHV1S40*01	92.8	CDRLenMismatch	-1.0	H1	13	H1-13-1	20	KASGFDFTWYTMN	BBBLBBAAABBBB
E	heavy	Oryctolagus.cuniculus	Rb_IGHV1S40*01	92.8	Rb_IGHV1S40*01	54.5	H2	11	H2-11-*	-1	SIGAGvYGSNY	BBBBEAABBBB
E	heavy	Oryctolagus.cuniculus	Rb_IGHV1S40*01	92.8	Rb_IGHV1S40*01	100.0	H3	11	H3-11-*	-1	ARDGINGGYDI	BBBABLLBBAB
E	heavy	Oryctolagus.cuniculus	Rb_IGHV1S40*01	92.8	Rb_IGHV1S40*01	85.7	H4	7	H4-7-1	14	KASSTTV	BABAABB
F	kappa	Oryctolagus.cuniculus	Rb_IGKV1S45*01	83.6	CDRLenMismatch	-1.0	L1	12	L1-12-*	-1	QSSQSVyNNRLA	BBABBBBEABBB
F	kappa	Oryctolagus.cuniculus	Rb_IGKV1S45*01	83.6	Rb_IGKV1S45*01	100.0	L2	8	L2-8-1	9	YSASTLAS	BLLABBBB
F	kappa	Oryctolagus.cuniculus	Rb_IGKV1S45*01	83.6	Rb_IGKV1S45*01	0.0	L3	12	L3-12-*	-1	HggyRSNDDRYA
F	kappa	Oryctolagus.cuniculus	Rb_IGKV1S45*01	83.6	Rb_IGKV1S45*01	100.0	L4	6	L4-6-*	-1	GSGTQF	EBEeBB
H	heavy	Oryctolagus.cuniculus	Rb_IGHV1S40*01	92.8	CDRLenMismatch	-1.0	H1	13	H1-13-1	20	KASGFDFTWYTMN	BBBLBBAAABBBB
H	heavy	Oryctolagus.cuniculus	Rb_IGHV1S40*01	92.8	Rb_IGHV1S40*01	54.5	H2	11	H2-11-*	-1	SIGAGvYGSNY	BBBBEAABBBB
H	heavy	Oryctolagus.cuniculus	Rb_IGHV1S40*01	92.8	Rb_IGHV1S40*01	100.0	H3	11	H3-11-*	-1	ARDGINGGYDI	BBBABLLBBAB
H	heavy	Oryctolagus.cuniculus	Rb_IGHV1S40*01	92.8	Rb_IGHV1S40*01	85.7	H4	7	H4-7-1	14	KASSTTV	BABAABB
L	kappa	Oryctolagus.cuniculus	Rb_IGKV1S45*01	83.6	CDRLenMismatch	-1.0	L1	12	L1-12-*	-1	QSSQSVyNNRLA	BBABBBBEABBB
L	kappa	Oryctolagus.cuniculus	Rb_IGKV1S45*01	83.6	Rb_IGKV1S45*01	100.0	L2	8	L2-8-1	9	YSASTLAS	BLLABBBB
L	kappa	Oryctolagus.cuniculus	Rb_IGKV1S45*01	83.6	Rb_IGKV1S45*01	0.0	L3	12	L3-12-*	-1	HggyRsNDDRYA
L	kappa	Oryctolagus.cuniculus	Rb_IGKV1S45*01	83.6	Rb_IGKV1S45*01	100.0	L4	6	L4-6-*	-1	GSGTQF	aBEeBB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022