PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 4QHU

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	lambda	Homo.sapiens	Hu_IGLV3-1*01	92.3	Hu_IGLV3-1*01	81.8	L1	11	L1-11-3	9	SGDNLGDKYAN	BBBLAAABBBB
A	lambda	Homo.sapiens	Hu_IGLV3-1*01	92.3	Hu_IGLV3-1*01	62.5	L2	8	L2-8-1	11	YDDIDRPS	BLEABBBB
A	lambda	Homo.sapiens	Hu_IGLV3-1*01	92.3	Hu_IGLV3-1*01	12.5	L3	11	L3-11-1	10	GSYDFFLGMIV	BBBBAAALBBB
A	lambda	Homo.sapiens	Hu_IGLV3-1*01	92.3	Hu_IGLV3-1*01	100.0	L4	6	L4-6-2	22	NSGNTA	BBEABB
B	heavy	Homo.sapiens	Hu_IGHV3-23*01	98.6	Hu_IGHV3-23*01	100.0	H1	13	H1-13-1	7	AASGFTFSSYAMS	BBBLBBAAABBBB
B	heavy	Homo.sapiens	Hu_IGHV3-23*01	98.6	Hu_IGHV3-23*01	50.0	H2	10	H2-10-*	-1	TISLTSGFTY	BBBABBLBBB
B	heavy	Homo.sapiens	Hu_IGHV3-23*01	98.6	Hu_IGHV3-23*01	50.0	H3	8	H3-8-2	7	ARQLTLDV	BBEAALAB
B	heavy	Homo.sapiens	Hu_IGHV3-23*01	98.6	Hu_IGHV3-23*01	100.0	H4	8	H4-8-1	6	RDNSKNTL	BBAAALBB
H	heavy	Homo.sapiens	Hu_IGHV3-23*01	98.6	Hu_IGHV3-23*01	100.0	H1	13	H1-13-1	7	AASGFTFSSYAMS	BBBLBBAAABBBB
H	heavy	Homo.sapiens	Hu_IGHV3-23*01	98.6	Hu_IGHV3-23*01	50.0	H2	10	H2-10-*	-1	TISLTSGFTY	BBBABBLBBB
H	heavy	Homo.sapiens	Hu_IGHV3-23*01	98.6	Hu_IGHV3-23*01	50.0	H3	8	H3-8-2	7	ARQLTLDV	BBEAALAB
H	heavy	Homo.sapiens	Hu_IGHV3-23*01	98.6	Hu_IGHV3-23*01	100.0	H4	8	H4-8-1	4	RDNSKNTL	BBAAALBB
L	lambda	Homo.sapiens	Hu_IGLV3-1*01	92.3	Hu_IGLV3-1*01	81.8	L1	11	L1-11-3	15	SGDNLGDKYAN	BBBLAAABBBB
L	lambda	Homo.sapiens	Hu_IGLV3-1*01	92.3	Hu_IGLV3-1*01	62.5	L2	8	L2-8-1	7	YDDIDRPS	BLEABBBB
L	lambda	Homo.sapiens	Hu_IGLV3-1*01	92.3	Hu_IGLV3-1*01	12.5	L3	11	L3-11-1	9	GSYDFFLGMIV	BBBBAAALBBB
L	lambda	Homo.sapiens	Hu_IGLV3-1*01	92.3	Hu_IGLV3-1*01	100.0	L4	6	L4-6-2	8	NSGNTA	BBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022