PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 4O5I

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
M	heavy	Homo.sapiens	Hu_IGHV1-69*06	90.4	CDRLenMismatch	-1.0	H1	12	H1-12-*	-1	RASGTFYKYAIN
M	heavy	Homo.sapiens	Hu_IGHV1-69*06	90.4	Hu_IGHV1-69*06	80.0	H2	10	H2-10-1	8	GIIPFFGTTN	BBBAAALBBB
M	heavy	Homo.sapiens	Hu_IGHV1-69*06	90.4	Hu_IGHV1-69*06	50.0	H3	25	H3-25-*	-1	AGPSiteshycldcaAKDYYYGLDV
M	heavy	Homo.sapiens	Hu_IGHV1-69*06	90.4	Hu_IGHV1-69*06	75.0	H4	8	H4-8-1	14	ADGSTNTA	BBAAALBB
N	lambda	Homo.sapiens	Hu_IGLV1-44*01	94.1	Hu_IGLV1-44*01	84.6	L1	13	L1-13-1	8	SGSRSNIGGNTVN	BBBAAAAAABBBB
N	lambda	Homo.sapiens	Hu_IGLV1-44*01	94.1	Hu_IGLV1-44*01	75.0	L2	8	L2-8-1	6	YSSNQRSS	BLLABBBB
N	lambda	Homo.sapiens	Hu_IGLV1-44*01	94.1	Hu_IGLV1-44*01	88.9	L3	11	L3-11-1	9	ASWDDSLNGVV	BBBBAAALBBB
N	lambda	Homo.sapiens	Hu_IGLV1-44*01	94.1	Hu_IGLV1-44*01	100.0	L4	6	L4-6-2	12	KSGTSA	BBEABB
O	heavy	Homo.sapiens	Hu_IGHV1-69*06	90.4	CDRLenMismatch	-1.0	H1	12	H1-12-*	-1	RASGTFYKYAIN
O	heavy	Homo.sapiens	Hu_IGHV1-69*06	90.4	Hu_IGHV1-69*06	80.0	H2	10	H2-10-1	8	GIIPFFGTTN	BBBAAALBBB
O	heavy	Homo.sapiens	Hu_IGHV1-69*06	90.4	Hu_IGHV1-69*06	50.0	H3	25	H3-25-*	-1	AGPSiteshycldcaAKDYYYGLDV
O	heavy	Homo.sapiens	Hu_IGHV1-69*06	90.4	Hu_IGHV1-69*06	75.0	H4	8	H4-8-1	14	ADGSTNTA	BBAAALBB
P	lambda	Homo.sapiens	Hu_IGLV1-44*01	94.1	Hu_IGLV1-44*01	84.6	L1	13	L1-13-1	8	SGSRSNIGGNTVN	BBBAAAAAABBBB
P	lambda	Homo.sapiens	Hu_IGLV1-44*01	94.1	Hu_IGLV1-44*01	75.0	L2	8	L2-8-1	6	YSSNQRSS	BLLABBBB
P	lambda	Homo.sapiens	Hu_IGLV1-44*01	94.1	Hu_IGLV1-44*01	88.9	L3	11	L3-11-1	9	ASWDDSLNGVV	BBBBAAALBBB
P	lambda	Homo.sapiens	Hu_IGLV1-44*01	94.1	Hu_IGLV1-44*01	100.0	L4	6	L4-6-2	12	KSGTSA	BBEABB
Q	heavy	Homo.sapiens	Hu_IGHV1-69*06	90.4	CDRLenMismatch	-1.0	H1	12	H1-12-*	-1	RASGTFYKYAIN
Q	heavy	Homo.sapiens	Hu_IGHV1-69*06	90.4	Hu_IGHV1-69*06	80.0	H2	10	H2-10-1	8	GIIPFFGTTN	BBBAAALBBB
Q	heavy	Homo.sapiens	Hu_IGHV1-69*06	90.4	Hu_IGHV1-69*06	50.0	H3	25	H3-25-*	-1	AGPSiteshycldcaAKDYYYGLDV
Q	heavy	Homo.sapiens	Hu_IGHV1-69*06	90.4	Hu_IGHV1-69*06	75.0	H4	8	H4-8-1	14	ADGSTNTA	BBAAALBB
R	lambda	Homo.sapiens	Hu_IGLV1-44*01	94.1	Hu_IGLV1-44*01	84.6	L1	13	L1-13-1	8	SGSRSNIGGNTVN	BBBAAAAAABBBB
R	lambda	Homo.sapiens	Hu_IGLV1-44*01	94.1	Hu_IGLV1-44*01	75.0	L2	8	L2-8-1	6	YSSNQRSS	BLLABBBB
R	lambda	Homo.sapiens	Hu_IGLV1-44*01	94.1	Hu_IGLV1-44*01	88.9	L3	11	L3-11-1	9	ASWDDSLNGVV	BBBBAAALBBB
R	lambda	Homo.sapiens	Hu_IGLV1-44*01	94.1	Hu_IGLV1-44*01	100.0	L4	6	L4-6-2	12	KSGTSA	BBEABB
S	heavy	Homo.sapiens	Hu_IGHV1-69*06	90.4	CDRLenMismatch	-1.0	H1	12	H1-12-*	-1	RASGTFYKYAIN
S	heavy	Homo.sapiens	Hu_IGHV1-69*06	90.4	Hu_IGHV1-69*06	80.0	H2	10	H2-10-1	8	GIIPFFGTTN	BBBAAALBBB
S	heavy	Homo.sapiens	Hu_IGHV1-69*06	90.4	Hu_IGHV1-69*06	50.0	H3	25	H3-25-*	-1	AGPSiteshycldcaAKDYYYGLDV
S	heavy	Homo.sapiens	Hu_IGHV1-69*06	90.4	Hu_IGHV1-69*06	75.0	H4	8	H4-8-1	14	ADGSTNTA	BBAAALBB
T	lambda	Homo.sapiens	Hu_IGLV1-44*01	94.1	Hu_IGLV1-44*01	84.6	L1	13	L1-13-1	8	SGSRSNIGGNTVN	BBBAAAAAABBBB
T	lambda	Homo.sapiens	Hu_IGLV1-44*01	94.1	Hu_IGLV1-44*01	75.0	L2	8	L2-8-1	6	YSSNQRSS	BLLABBBB
T	lambda	Homo.sapiens	Hu_IGLV1-44*01	94.1	Hu_IGLV1-44*01	88.9	L3	11	L3-11-1	9	ASWDDSLNGVV	BBBBAAALBBB
T	lambda	Homo.sapiens	Hu_IGLV1-44*01	94.1	Hu_IGLV1-44*01	100.0	L4	6	L4-6-2	12	KSGTSA	BBEABB
U	heavy	Homo.sapiens	Hu_IGHV1-69*06	90.4	CDRLenMismatch	-1.0	H1	12	H1-12-*	-1	RASGTFYKYAIN
U	heavy	Homo.sapiens	Hu_IGHV1-69*06	90.4	Hu_IGHV1-69*06	80.0	H2	10	H2-10-1	8	GIIPFFGTTN	BBBAAALBBB
U	heavy	Homo.sapiens	Hu_IGHV1-69*06	90.4	Hu_IGHV1-69*06	50.0	H3	25	H3-25-*	-1	AGPSiteshycldcaAKDYYYGLDV
U	heavy	Homo.sapiens	Hu_IGHV1-69*06	90.4	Hu_IGHV1-69*06	75.0	H4	8	H4-8-1	14	ADGSTNTA	BBAAALBB
V	lambda	Homo.sapiens	Hu_IGLV1-44*01	94.1	Hu_IGLV1-44*01	84.6	L1	13	L1-13-1	8	SGSRSNIGGNTVN	BBBAAAAAABBBB
V	lambda	Homo.sapiens	Hu_IGLV1-44*01	94.1	Hu_IGLV1-44*01	75.0	L2	8	L2-8-1	6	YSSNQRSS	BLLABBBB
V	lambda	Homo.sapiens	Hu_IGLV1-44*01	94.1	Hu_IGLV1-44*01	88.9	L3	11	L3-11-1	9	ASWDDSLNGVV	BBBBAAALBBB
V	lambda	Homo.sapiens	Hu_IGLV1-44*01	94.1	Hu_IGLV1-44*01	100.0	L4	6	L4-6-2	12	KSGTSA	BBEABB
W	heavy	Homo.sapiens	Hu_IGHV1-69*06	90.4	CDRLenMismatch	-1.0	H1	12	H1-12-*	-1	RASGTFYKYAIN
W	heavy	Homo.sapiens	Hu_IGHV1-69*06	90.4	Hu_IGHV1-69*06	80.0	H2	10	H2-10-1	8	GIIPFFGTTN	BBBAAALBBB
W	heavy	Homo.sapiens	Hu_IGHV1-69*06	90.4	Hu_IGHV1-69*06	50.0	H3	25	H3-25-*	-1	AGPSiteshycldcaAKDYYYGLDV
W	heavy	Homo.sapiens	Hu_IGHV1-69*06	90.4	Hu_IGHV1-69*06	75.0	H4	8	H4-8-1	14	ADGSTNTA	BBAAALBB
X	lambda	Homo.sapiens	Hu_IGLV1-44*01	94.1	Hu_IGLV1-44*01	84.6	L1	13	L1-13-1	8	SGSRSNIGGNTVN	BBBAAAAAABBBB
X	lambda	Homo.sapiens	Hu_IGLV1-44*01	94.1	Hu_IGLV1-44*01	75.0	L2	8	L2-8-1	6	YSSNQRSS	BLLABBBB
X	lambda	Homo.sapiens	Hu_IGLV1-44*01	94.1	Hu_IGLV1-44*01	88.9	L3	11	L3-11-1	9	ASWDDSLNGVV	BBBBAAALBBB
X	lambda	Homo.sapiens	Hu_IGLV1-44*01	94.1	Hu_IGLV1-44*01	100.0	L4	6	L4-6-2	12	KSGTSA	BBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022