PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 4M8Q

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	heavy	Homo.sapiens	Hu_IGHV1-69*06	100.0	Hu_IGHV1-69*06	100.0	H1	13	H1-13-1	17	KASGGTFSSYAIS	BBBLBBAAABBBB
A	heavy	Homo.sapiens	Hu_IGHV1-69*06	100.0	Hu_IGHV1-69*06	100.0	H2	10	H2-10-1	18	GIIPIFGTAN	BBBAAALBBB
A	heavy	Homo.sapiens	Hu_IGHV1-69*06	100.0	Hu_IGHV1-69*06	100.0	H3	20	H3-20-*	-1	AREGTTGWGwlgkpigAFAY
A	heavy	Homo.sapiens	Hu_IGHV1-69*06	100.0	Hu_IGHV1-69*06	100.0	H4	8	H4-8-1	15	ADKSTSTA	BBAAALBB
B	kappa	Homo.sapiens	Hu_IGKV3-20*01	100.0	Hu_IGKV3-20*01	100.0	L1	12	L1-12-1	12	RASQSVSsSYLA	BBABBBBAAABB
B	kappa	Homo.sapiens	Hu_IGKV3-20*01	100.0	Hu_IGKV3-20*01	100.0	L2	8	L2-8-1	13	YGASSRAT	BLEABBBB
B	kappa	Homo.sapiens	Hu_IGKV3-20*01	100.0	Hu_IGKV3-20*01	100.0	L3	9	L3-9-cis7-1	9	QQYGSSPST	BBAABBbBB
B	kappa	Homo.sapiens	Hu_IGKV3-20*01	100.0	Hu_IGKV3-20*01	100.0	L4	6	L4-6-1	19	GSGTDF	EBEABB
H	heavy	Homo.sapiens	Hu_IGHV1-69*06	100.0	Hu_IGHV1-69*06	100.0	H1	13	H1-13-1	17	KASGGTFSSYAIS	BBBLBBAAABBBB
H	heavy	Homo.sapiens	Hu_IGHV1-69*06	100.0	Hu_IGHV1-69*06	100.0	H2	10	H2-10-1	16	GIIPIFGTAN	BBBAAALBBB
H	heavy	Homo.sapiens	Hu_IGHV1-69*06	100.0	Hu_IGHV1-69*06	100.0	H3	20	H3-20-*	-1	AREGTTGWGWlgkpigAFAY
H	heavy	Homo.sapiens	Hu_IGHV1-69*06	100.0	Hu_IGHV1-69*06	100.0	H4	8	H4-8-1	11	ADKSTSTA	BBAAALBB
L	kappa	Homo.sapiens	Hu_IGKV3-20*01	100.0	Hu_IGKV3-20*01	100.0	L1	12	L1-12-1	10	RASQSVSsSYLA	BBABBBBAAABB
L	kappa	Homo.sapiens	Hu_IGKV3-20*01	100.0	Hu_IGKV3-20*01	100.0	L2	8	L2-8-1	14	YGASSRAT	BLEABBBB
L	kappa	Homo.sapiens	Hu_IGKV3-20*01	100.0	Hu_IGKV3-20*01	100.0	L3	9	L3-9-cis7-1	9	QQYGSSPST	BBAABBbBB
L	kappa	Homo.sapiens	Hu_IGKV3-20*01	100.0	Hu_IGKV3-20*01	100.0	L4	6	L4-6-1	19	GSGTDF	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022