PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 4KAQ

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
H	heavy	Homo.sapiens.Mus.musculus	Mo_IGHV1S121*01	98.4	Mo_IGHV1S121*01	100.0	H1	13	H1-13-1	8	KASGYTFTSYNMH	BBBLBBAAABBBB
H	heavy	Homo.sapiens.Mus.musculus	Mo_IGHV1S121*01	98.4	Mo_IGHV1S121*01	100.0	H2	10	H2-10-1	15	AIYPGNGDTS	BBBAAALBBB
H	heavy	Homo.sapiens.Mus.musculus	Mo_IGHV1S121*01	98.4	Mo_IGHV1S121*01	0.0	H3	14	H3-14-2	14	ARSTYYGGDWYFNV	BBBBBBLLBBBBAB
H	heavy	Homo.sapiens.Mus.musculus	Mo_IGHV1S121*01	98.4	Mo_IGHV1S121*01	100.0	H4	8	H4-8-1	16	ADKSSSTA	BBAAALBB
L	kappa	Homo.sapiens.Mus.musculus	Mo_IGKV4-72*01	97.1	Mo_IGKV4-72*01	90.0	L1	10	L1-10-1	9	RASSSVSYIH	BBABBBABBB
L	kappa	Homo.sapiens.Mus.musculus	Mo_IGKV4-72*01	97.1	Mo_IGKV4-72*01	100.0	L2	8	L2-8-1	6	YATSNLAS	BLEABBBB
L	kappa	Homo.sapiens.Mus.musculus	Mo_IGKV4-72*01	97.1	Mo_IGKV4-72*01	87.5	L3	9	L3-9-cis7-1	8	QQWTSNPPT	BBAABBbBB
L	kappa	Homo.sapiens.Mus.musculus	Mo_IGKV4-72*01	97.1	Mo_IGKV4-72*01	100.0	L4	6	L4-6-1	5	GSGTSY	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022