PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 4K8R

#CDRs = 8; #Clusters = 13.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
C	kappa	Homo.sapiens	Hu_IGKV1-13*02	100.0	Hu_IGKV1-13*02	100.0	L1	11	L1-11-1	13	RASQGISSALA	BBABBAEABBB
C	kappa	Homo.sapiens	Hu_IGKV1-13*02	100.0	Hu_IGKV1-13*02	100.0	L2	8	L2-8-1	15	YDASSLES	BLLABBBB
C	kappa	Homo.sapiens	Hu_IGKV1-13*02	100.0	Hu_IGKV1-13*02	85.7	L3	9	L3-9-2	9	QQFNSYLIT	BBAABABBB
C	kappa	Homo.sapiens	Hu_IGKV1-13*02	100.0	Hu_IGKV1-13*02	100.0	L4	6	L4-6-1	12	GSGTDF	EBEABB
D	heavy	Homo.sapiens	Hu_IGHV3-13*01	98.6	Hu_IGHV3-13*01	100.0	H1	13	H1-13-1	16	AASGFTFSSYDMH	BBBLBBAAABBBB
D	heavy	Homo.sapiens	Hu_IGHV3-13*01	98.6	Hu_IGHV3-13*01	100.0	H2	9	H2-9-1	18	AIGTAGDTY	BBBAALBBB
D	heavy	Homo.sapiens	Hu_IGHV3-13*01	98.6	Hu_IGHV3-13*01	50.0	H3	22	H3-22-*	-1	VREGTYyhdsgsdnYYSYGMDV
D	heavy	Homo.sapiens	Hu_IGHV3-13*01	98.6	Hu_IGHV3-13*01	100.0	H4	8	H4-8-1	12	RENAKNSL	BBAAALBB
H	heavy	Homo.sapiens	Hu_IGHV3-21*01	98.6	Hu_IGHV3-21*01	100.0	H1	13	H1-13-1	12	AASGFTFSSYSMN	BBBLBBAAABBBB
H	heavy	Homo.sapiens	Hu_IGHV3-21*01	98.6	Hu_IGHV3-21*01	90.0	H2	10	H2-10-2	15	SISSSSSYIS	BBBAALABBB
H	heavy	Homo.sapiens	Hu_IGHV3-21*01	98.6	Hu_IGHV3-21*01	100.0	H3	16	H3-16-*	-1	ARDYDfwSAYYDAFDV
H	heavy	Homo.sapiens	Hu_IGHV3-21*01	98.6	Hu_IGHV3-21*01	100.0	H4	8	H4-8-1	8	RDNAKNSL	BBAAALBB
L	lambda	Homo.sapiens	Hu_IGLV1-40*01	100.0	Hu_IGLV1-40*01	100.0	L1	14	L1-14-3	9	TGSSSNIGAgYDVH	BBBAAAAAALBBBB
L	lambda	Homo.sapiens	Hu_IGLV1-40*01	100.0	Hu_IGLV1-40*01	87.5	L2	8	L2-8-1	14	SGNSNRPS	BLLABBBB
L	lambda	Homo.sapiens	Hu_IGLV1-40*01	100.0	Hu_IGLV1-40*01	100.0	L3	11	L3-11-1	10	QSYDSSLSGSV	BBBBAAALBBB
L	lambda	Homo.sapiens	Hu_IGLV1-40*01	100.0	Hu_IGLV1-40*01	100.0	L4	6	L4-6-2	11	KSGTSA	BBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022