PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 4IOF

#CDRs = 8; #Clusters = 9.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
C	heavy	Mus.musculus	Hu_IGHV3-66*01	94.5	Mo_IGHV5-12-1*01	61.5	H1	13	H1-13-1	19	AASGFNVSSYSIH	BBBLBBAAABBBB
C	heavy	Mus.musculus	Hu_IGHV3-66*01	94.5	Mo_IGHV5-12-1*01	60.0	H2	10	H2-10-1	16	SISSYYGSTS	BBBAAALBBB
C	heavy	Mus.musculus	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	100.0	H3	22	H3-22-*	-1	ARDRvmyywsfsKYGYPYGMDY
C	heavy	Mus.musculus	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	62.5	H4	8	H4-8-*	-1	ADTskNTA
D	kappa	Mus.musculus	Hu_IGKV1-39*01	98.6	Mo_IGKV6-17*01	72.7	L1	11	L1-11-*	-1	RAsqsVSSAVA
D	kappa	Mus.musculus	Hu_IGKV1-39*01	98.6	Mo_IGKV6-17*01	50.0	L2	8	L2-8-*	-1	YSTSSLYS	ABAABBBB
D	kappa	Mus.musculus	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	42.9	L3	10	L3-10-*	-1	QQSSpSFLIT	BBBBBLLBBB
D	kappa	Mus.musculus	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	83.3	L4	6	L4-6-*	-1	RSgTDF
E	heavy	Mus.musculus	Hu_IGHV3-66*01	94.5	Mo_IGHV5-12-1*01	61.5	H1	13	H1-13-1	19	AASGFNVSSYSIH	BBBLBBAAABBBB
E	heavy	Mus.musculus	Hu_IGHV3-66*01	94.5	Mo_IGHV5-12-1*01	60.0	H2	10	H2-10-1	16	SISSYYGSTS	BBBAAALBBB
E	heavy	Mus.musculus	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	100.0	H3	22	H3-22-*	-1	ARDRvmyywsfsKYGYPYGMDY
E	heavy	Mus.musculus	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	62.5	H4	8	H4-8-1	15	ADTSKNTA	BBAAALBB
F	kappa	Mus.musculus	Hu_IGKV1-39*01	98.6	Mo_IGKV6-17*01	72.7	L1	11	L1-11-*	-1	RASQSVSSAVA	BBABAABABBB
F	kappa	Mus.musculus	Hu_IGKV1-39*01	98.6	Mo_IGKV6-17*01	50.0	L2	8	L2-8-*	-1	YSTSSLYS	ABAABBBB
F	kappa	Mus.musculus	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	42.9	L3	10	L3-10-*	-1	QQSSpSFLIT	BBBBBbLBBB
F	kappa	Mus.musculus	Hu_IGKV1-39*01	98.6	Hu_IGKV1-39*01	83.3	L4	6	L4-6-*	-1	RSGTDF	BAEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022