PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 4I77

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
H	heavy	Homo.sapiens	Hu_IGHV2-70*17	94.5	Mo_IGHV2-6-4*01	84.6	H1	13	H1-13-1	16	TVSGFSLSAYSVN	BBBLBBAAABBBB
H	heavy	Homo.sapiens	Hu_IGHV2-70*17	94.5	Mo_IGHV2-6-4*01	55.6	H2	9	H2-9-1	9	MIWGDGKIV	BBBAALBBB
H	heavy	Homo.sapiens	Hu_IGHV2-70*17	94.5	Hu_IGHV2-70*17	33.3	H3	12	H3-12-*	-1	AGDGYYPYAMDN	BBBBBBaLBBAB
H	heavy	Homo.sapiens	Hu_IGHV2-70*17	94.5	Hu_IGHV2-70*17	100.0	H4	8	H4-8-1	8	KDTSKNQV	BBAAALBB
L	kappa	Homo.sapiens	Hu_IGKV4-1*01	98.6	Mo_IGKV3-10*01	93.3	L1	15	L1-15-1	6	RASKSVDSYgnsfMH	BBABBABBLLBBBBB
L	kappa	Homo.sapiens	Hu_IGKV4-1*01	98.6	Mo_IGKV3-10*01	100.0	L2	8	L2-8-1	6	YLASNLES	BLLABBBB
L	kappa	Homo.sapiens	Hu_IGKV4-1*01	98.6	Hu_IGKV4-1*01	42.9	L3	9	L3-9-cis7-1	9	QQNNEDPRT	BBAABBbBB
L	kappa	Homo.sapiens	Hu_IGKV4-1*01	98.6	Hu_IGKV4-1*01	100.0	L4	6	L4-6-1	8	GSGTDF	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022