PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 4HKB

#CDRs = 8; #Clusters = 9.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	heavy	Homo.sapiens	Hu_IGHV1-2*04	94.5	Hu_IGHV1-2*04	76.9	H1	13	H1-13-1	12	KASGYTFTDNYIH	BBBLBBAAABBBB
A	heavy	Homo.sapiens	Hu_IGHV1-2*04	94.5	Hu_IGHV1-2*04	70.0	H2	10	H2-10-1	13	WIHPNSGATK	BBBAAALBBB
A	heavy	Homo.sapiens	Hu_IGHV1-2*04	94.5	Hu_IGHV1-2*04	100.0	H3	19	H3-19-*	-1	ARAgleprSVDYYFYGLDV
A	heavy	Homo.sapiens	Hu_IGHV1-2*04	94.5	Hu_IGHV1-2*04	87.5	H4	8	H4-8-1	11	RDTSISTV	BBAAALBB
B	lambda	Homo.sapiens	Hu_IGLV3-21*02	93.8	Hu_IGLV3-21*02	72.7	L1	11	L1-11-*	-1	GGNNIGRKRVD	BBAAAAABBBB
B	lambda	Homo.sapiens	Hu_IGLV3-21*02	93.8	Hu_IGLV3-21*02	87.5	L2	8	L2-8-*	-1	yedsdrps
B	lambda	Homo.sapiens	Hu_IGLV3-21*02	93.8	Hu_IGLV3-21*02	88.9	L3	11	L3-11-1	23	QVWDSDSDHVV	BBBBAAALBBB
B	lambda	Homo.sapiens	Hu_IGLV3-21*02	93.8	Hu_IGLV3-21*02	83.3	L4	6	L4-6-*	-1	NSGTTA	BALABB
C	heavy	Homo.sapiens	Hu_IGHV1-2*04	94.5	Hu_IGHV1-2*04	76.9	H1	13	H1-13-1	13	KASGYTFTDNYIH	BBBLBBAAABBBB
C	heavy	Homo.sapiens	Hu_IGHV1-2*04	94.5	Hu_IGHV1-2*04	70.0	H2	10	H2-10-1	14	WIHPNSGATK	BBBAAALBBB
C	heavy	Homo.sapiens	Hu_IGHV1-2*04	94.5	Hu_IGHV1-2*04	100.0	H3	19	H3-19-*	-1	ARAgleprSVDYYFYGLDV
C	heavy	Homo.sapiens	Hu_IGHV1-2*04	94.5	Hu_IGHV1-2*04	87.5	H4	8	H4-8-*	-1	RDTSISTV	BALAALBB
D	lambda	Homo.sapiens	Hu_IGLV3-21*02	93.8	Hu_IGLV3-21*02	72.7	L1	11	L1-11-*	-1	GGNNIGRKRVD	BBBLAAABBBB
D	lambda	Homo.sapiens	Hu_IGLV3-21*02	93.8	Hu_IGLV3-21*02	87.5	L2	8	L2-8-*	-1	yedsdrps
D	lambda	Homo.sapiens	Hu_IGLV3-21*02	93.8	Hu_IGLV3-21*02	88.9	L3	11	L3-11-1	24	QVWDSDSDHVV	BBBBAAALBBB
D	lambda	Homo.sapiens	Hu_IGLV3-21*02	93.8	Hu_IGLV3-21*02	83.3	L4	6	L4-6-*	-1	NSGTTA	BALABB
E	heavy	Homo.sapiens	Hu_IGHV1-2*04	94.5	Hu_IGHV1-2*04	76.9	H1	13	H1-13-1	12	KASGYTFTDNYIH	BBBLBBAAABBBB
E	heavy	Homo.sapiens	Hu_IGHV1-2*04	94.5	Hu_IGHV1-2*04	70.0	H2	10	H2-10-1	14	WIHPNSGATK	BBBAAALBBB
E	heavy	Homo.sapiens	Hu_IGHV1-2*04	94.5	Hu_IGHV1-2*04	100.0	H3	19	H3-19-*	-1	ARAgleprSVDYYFYGLDV
E	heavy	Homo.sapiens	Hu_IGHV1-2*04	94.5	Hu_IGHV1-2*04	87.5	H4	8	H4-8-*	-1	RDTSISTV	BALAALBB
F	lambda	Homo.sapiens	Hu_IGLV3-21*02	93.8	Hu_IGLV3-21*02	72.7	L1	11	L1-11-*	-1	GGNNIGRKRVD	BBBLAAABBBB
F	lambda	Homo.sapiens	Hu_IGLV3-21*02	93.8	Hu_IGLV3-21*02	87.5	L2	8	L2-8-*	-1	yedsdrps
F	lambda	Homo.sapiens	Hu_IGLV3-21*02	93.8	Hu_IGLV3-21*02	88.9	L3	11	L3-11-1	23	QVWDSDSDHVV	BBBBAAALBBB
F	lambda	Homo.sapiens	Hu_IGLV3-21*02	93.8	Hu_IGLV3-21*02	83.3	L4	6	L4-6-*	-1	NSGTTA	BALABB
G	heavy	Homo.sapiens	Hu_IGHV1-2*04	94.5	Hu_IGHV1-2*04	76.9	H1	13	H1-13-1	12	KASGYTFTDNYIH	BBBLBBAAABBBB
G	heavy	Homo.sapiens	Hu_IGHV1-2*04	94.5	Hu_IGHV1-2*04	70.0	H2	10	H2-10-1	14	WIHPNSGATK	BBBAAALBBB
G	heavy	Homo.sapiens	Hu_IGHV1-2*04	94.5	Hu_IGHV1-2*04	100.0	H3	19	H3-19-*	-1	ARAgleprSVDYYFYGLDV
G	heavy	Homo.sapiens	Hu_IGHV1-2*04	94.5	Hu_IGHV1-2*04	87.5	H4	8	H4-8-*	-1	RDTSISTV	BALAALBB
H	lambda	Homo.sapiens	Hu_IGLV3-21*02	93.8	Hu_IGLV3-21*02	72.7	L1	11	L1-11-*	-1	GGNNIGRKRVD	BBBLAAABBBB
H	lambda	Homo.sapiens	Hu_IGLV3-21*02	93.8	Hu_IGLV3-21*02	87.5	L2	8	L2-8-*	-1	yedsdrps
H	lambda	Homo.sapiens	Hu_IGLV3-21*02	93.8	Hu_IGLV3-21*02	88.9	L3	11	L3-11-1	23	QVWDSDSDHVV	BBBBAAALBBB
H	lambda	Homo.sapiens	Hu_IGLV3-21*02	93.8	Hu_IGLV3-21*02	83.3	L4	6	L4-6-*	-1	NSGTTA	BALABB
I	heavy	Homo.sapiens	Hu_IGHV1-2*04	94.5	Hu_IGHV1-2*04	76.9	H1	13	H1-13-1	12	KASGYTFTDNYIH	BBBLBBAAABBBB
I	heavy	Homo.sapiens	Hu_IGHV1-2*04	94.5	Hu_IGHV1-2*04	70.0	H2	10	H2-10-1	14	WIHPNSGATK	BBBAAALBBB
I	heavy	Homo.sapiens	Hu_IGHV1-2*04	94.5	Hu_IGHV1-2*04	100.0	H3	19	H3-19-*	-1	ARAgleprSVDYYFYGLDV
I	heavy	Homo.sapiens	Hu_IGHV1-2*04	94.5	Hu_IGHV1-2*04	87.5	H4	8	H4-8-*	-1	RDTSISTV	BAEAALBB
J	heavy	Homo.sapiens	Hu_IGHV1-2*04	94.5	Hu_IGHV1-2*04	76.9	H1	13	H1-13-1	12	KASGYTFTDNYIH	BBBLBBAAABBBB
J	heavy	Homo.sapiens	Hu_IGHV1-2*04	94.5	Hu_IGHV1-2*04	70.0	H2	10	H2-10-1	14	WIHPNSGATK	BBBAAALBBB
J	heavy	Homo.sapiens	Hu_IGHV1-2*04	94.5	Hu_IGHV1-2*04	100.0	H3	19	H3-19-*	-1	ARAgleprSVDYYFYGLDV
J	heavy	Homo.sapiens	Hu_IGHV1-2*04	94.5	Hu_IGHV1-2*04	87.5	H4	8	H4-8-*	-1	RDTSISTV	BAEAALBB
K	lambda	Homo.sapiens	Hu_IGLV3-21*02	93.8	Hu_IGLV3-21*02	72.7	L1	11	L1-11-*	-1	GGNNIGRKRVD	BBBLAAABBBB
K	lambda	Homo.sapiens	Hu_IGLV3-21*02	93.8	Hu_IGLV3-21*02	87.5	L2	8	L2-8-*	-1	yedsdrps
K	lambda	Homo.sapiens	Hu_IGLV3-21*02	93.8	Hu_IGLV3-21*02	88.9	L3	11	L3-11-1	24	QVWDSDSDHVV	BBBBAAALBBB
K	lambda	Homo.sapiens	Hu_IGLV3-21*02	93.8	Hu_IGLV3-21*02	83.3	L4	6	L4-6-*	-1	NSGTTA	BALABB
N	lambda	Homo.sapiens	Hu_IGLV3-21*02	93.8	Hu_IGLV3-21*02	72.7	L1	11	L1-11-*	-1	GGNNIGRKRVD	BBBLAAABBBB
N	lambda	Homo.sapiens	Hu_IGLV3-21*02	93.8	Hu_IGLV3-21*02	87.5	L2	8	L2-8-*	-1	yedsdrps
N	lambda	Homo.sapiens	Hu_IGLV3-21*02	93.8	Hu_IGLV3-21*02	88.9	L3	11	L3-11-1	23	QVWDSDSDHVV	BBBBAAALBBB
N	lambda	Homo.sapiens	Hu_IGLV3-21*02	93.8	Hu_IGLV3-21*02	83.3	L4	6	L4-6-*	-1	NSGTTA	BALABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022