PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 4EDX

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	kappa	Mus.musculus	Mo_IGKV10-96*02	100.0	Mo_IGKV10-96*02	90.9	L1	11	L1-11-1	8	RASQDISNHLN	BBABBAEABBB
A	kappa	Mus.musculus	Mo_IGKV10-96*02	100.0	Mo_IGKV10-96*02	75.0	L2	8	L2-8-1	9	YYISRFHS	BLEABBBB
A	kappa	Mus.musculus	Mo_IGKV10-96*02	100.0	Mo_IGKV10-96*02	71.4	L3	9	L3-9-cis7-1	8	QQSKTLPYT	BBAABBbBB
A	kappa	Mus.musculus	Mo_IGKV10-96*02	100.0	Mo_IGKV10-96*02	100.0	L4	6	L4-6-2	13	GSGTDY	BBEABB
B	heavy	Mus.musculus	Mo_IGHV2-6-7*01	95.9	Mo_IGHV2-6-7*01	76.9	H1	13	H1-13-1	12	TVSGFSLIGYDIN	BBBLBBAAABBBB
B	heavy	Mus.musculus	Mo_IGHV2-6-7*01	95.9	Mo_IGHV2-6-7*01	88.9	H2	9	H2-9-1	11	MIWGDGTTD	BBBAALBBB
B	heavy	Mus.musculus	Mo_IGHV2-6-7*01	95.9	Mo_IGHV2-6-7*01	100.0	H3	15	H3-15-*	-1	ARGGYYyGTSYYFDY
B	heavy	Mus.musculus	Mo_IGHV2-6-7*01	95.9	Mo_IGHV2-6-7*01	100.0	H4	8	H4-8-1	5	KDNSKSQV	BBAAALBB
H	heavy	Mus.musculus	Mo_IGHV2-6-7*01	95.9	Mo_IGHV2-6-7*01	76.9	H1	13	H1-13-1	12	TVSGFSLIGYDIN	BBBLBBAAABBBB
H	heavy	Mus.musculus	Mo_IGHV2-6-7*01	95.9	Mo_IGHV2-6-7*01	88.9	H2	9	H2-9-1	11	MIWGDGTTD	BBBAALBBB
H	heavy	Mus.musculus	Mo_IGHV2-6-7*01	95.9	Mo_IGHV2-6-7*01	100.0	H3	15	H3-15-*	-1	ARGGYYyGTSYYFDY
H	heavy	Mus.musculus	Mo_IGHV2-6-7*01	95.9	Mo_IGHV2-6-7*01	100.0	H4	8	H4-8-1	5	KDNSKSQV	BBAAALBB
L	kappa	Mus.musculus	Mo_IGKV10-96*02	100.0	Mo_IGKV10-96*02	90.9	L1	11	L1-11-1	9	RASQDISNHLN	BBABBAEABBB
L	kappa	Mus.musculus	Mo_IGKV10-96*02	100.0	Mo_IGKV10-96*02	75.0	L2	8	L2-8-1	9	YYISRFHS	BLLABBBB
L	kappa	Mus.musculus	Mo_IGKV10-96*02	100.0	Mo_IGKV10-96*02	71.4	L3	9	L3-9-cis7-1	8	QQSKTLPYT	BBAABBbBB
L	kappa	Mus.musculus	Mo_IGKV10-96*02	100.0	Mo_IGKV10-96*02	100.0	L4	6	L4-6-2	13	GSGTDY	BBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022