PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 4CNI

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	heavy	Homo.sapiens	Hu_IGHV3-72*01	94.5	Ra_IGHV6-22*01	92.3	H1	13	H1-13-1	10	AASGFNFNDYFMN	BBBLBBAAABBBB
A	heavy	Homo.sapiens	Hu_IGHV3-72*01	94.5	Ra_IGHV6-22*01	75.0	H2	12	H2-12-1	9	QMRNKNYQygTY	BBBBAAALLBBB
A	heavy	Homo.sapiens	Hu_IGHV3-72*01	94.5	Hu_IGHV3-72*01	100.0	H3	11	H3-11-1	16	ARESYYGFTSY	BBBBAALBBAB
A	heavy	Homo.sapiens	Hu_IGHV3-72*01	94.5	Hu_IGHV3-72*01	100.0	H4	8	H4-8-1	4	RDDSKNSL	BBAAALBB
B	kappa	Homo.sapiens	Hu_IGKV1-6*01	100.0	Ra_IGKV12S1*01	81.8	L1	11	L1-11-1	5	QASQDIGISLS	BBABBAEABBB
B	kappa	Homo.sapiens	Hu_IGKV1-6*01	100.0	Ra_IGKV12S1*01	62.5	L2	8	L2-8-1	6	YNANNLAD	BLLABBBB
B	kappa	Homo.sapiens	Hu_IGKV1-6*01	100.0	Hu_IGKV1-6*01	42.9	L3	9	L3-9-cis7-1	14	LQHNSAPYT	BBAABBbBB
B	kappa	Homo.sapiens	Hu_IGKV1-6*01	100.0	Hu_IGKV1-6*01	100.0	L4	6	L4-6-1	6	GSGTDF	EBEABB
H	heavy	Homo.sapiens	Hu_IGHV3-72*01	94.5	Ra_IGHV6-22*01	92.3	H1	13	H1-13-1	10	AASGFNFNDYFMN	BBBLBBAAABBBB
H	heavy	Homo.sapiens	Hu_IGHV3-72*01	94.5	Ra_IGHV6-22*01	75.0	H2	12	H2-12-1	13	QMRNKNYQygTY	BBBBAAALLBBB
H	heavy	Homo.sapiens	Hu_IGHV3-72*01	94.5	Hu_IGHV3-72*01	100.0	H3	11	H3-11-1	17	ARESYYGFTSY	BBBBAALBBAB
H	heavy	Homo.sapiens	Hu_IGHV3-72*01	94.5	Hu_IGHV3-72*01	100.0	H4	8	H4-8-1	5	RDDSKNSL	BBAAALBB
L	kappa	Homo.sapiens	Hu_IGKV1-6*01	100.0	Ra_IGKV12S1*01	81.8	L1	11	L1-11-1	4	QASQDIGISLS	BBABBAEABBB
L	kappa	Homo.sapiens	Hu_IGKV1-6*01	100.0	Ra_IGKV12S1*01	62.5	L2	8	L2-8-1	5	YNANNLAD	BLLABBBB
L	kappa	Homo.sapiens	Hu_IGKV1-6*01	100.0	Hu_IGKV1-6*01	42.9	L3	9	L3-9-cis7-1	15	LQHNSAPYT	BBAABBbBB
L	kappa	Homo.sapiens	Hu_IGKV1-6*01	100.0	Hu_IGKV1-6*01	100.0	L4	6	L4-6-1	7	GSGTDF	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022