PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 3WLW

#CDRs = 8; #Clusters = 9.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
C	heavy	Homo.sapiens	Hu_IGHV1-18*01	94.5	Hu_IGHV1-18*01	69.2	H1	13	H1-13-1	12	KGSGYSFTSYWIG	BBBLBBAAABBBB
C	heavy	Homo.sapiens	Hu_IGHV1-18*01	94.5	Hu_IGHV1-18*01	100.0	H2	10	H2-10-1	18	WISAYNGNTN	BBBAAALBBB
C	heavy	Homo.sapiens	Hu_IGHV1-18*01	94.5	Hu_IGHV1-18*01	100.0	H3	10	H3-10-*	-1	AREGDGAFDY	BBBBBLBBAB
C	heavy	Homo.sapiens	Hu_IGHV1-18*01	94.5	Hu_IGHV1-18*01	100.0	H4	8	H4-8-1	11	TDTSTSTA	BBAAALBB
D	lambda	Homo.sapiens	Hu_IGLV2-14*01	100.0	Hu_IGLV2-14*01	100.0	L1	14	L1-14-*	-1	TGTSSDVGgYNYVS	bEBAAAAAAALBBB
D	lambda	Homo.sapiens	Hu_IGLV2-14*01	100.0	Hu_IGLV2-14*01	75.0	L2	8	L2-8-*	-1	YDVSKRPS	BLEBBBBB
D	lambda	Homo.sapiens	Hu_IGLV2-14*01	100.0	Hu_IGLV2-14*01	100.0	L3	10	L3-10-1	16	SSYTSSSTLV	BBBBAALBBB
D	lambda	Homo.sapiens	Hu_IGLV2-14*01	100.0	Hu_IGLV2-14*01	100.0	L4	6	L4-6-*	-1	KSGNTA	EBBaBl
H	heavy	Homo.sapiens	Hu_IGHV1-18*01	94.5	Hu_IGHV1-18*01	69.2	H1	13	H1-13-1	13	KGSGYSFTSYWIG	BBBLBBAAABBBB
H	heavy	Homo.sapiens	Hu_IGHV1-18*01	94.5	Hu_IGHV1-18*01	100.0	H2	10	H2-10-1	15	WISAYNGNTN	BBBAAALBBB
H	heavy	Homo.sapiens	Hu_IGHV1-18*01	94.5	Hu_IGHV1-18*01	100.0	H3	10	H3-10-*	-1	AREGDGAFDY	BBBBBLBBAB
H	heavy	Homo.sapiens	Hu_IGHV1-18*01	94.5	Hu_IGHV1-18*01	100.0	H4	8	H4-8-1	13	TDTSTSTA	BBAAALBB
L	lambda	Homo.sapiens	Hu_IGLV2-14*01	100.0	Hu_IGLV2-14*01	100.0	L1	14	L1-14-*	-1	TGTSSDVGgYNYVS	bBBAAAAAABABBB
L	lambda	Homo.sapiens	Hu_IGLV2-14*01	100.0	Hu_IGLV2-14*01	75.0	L2	8	L2-8-4	22	YDVSKRPS	BEABBBBB
L	lambda	Homo.sapiens	Hu_IGLV2-14*01	100.0	Hu_IGLV2-14*01	100.0	L3	10	L3-10-1	20	SSYTSSSTLV	BBBBAALBBB
L	lambda	Homo.sapiens	Hu_IGLV2-14*01	100.0	Hu_IGLV2-14*01	100.0	L4	6	L4-6-*	-1	KSGNTA	EBBaBl

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022