PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 3QWO

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	heavy	Mus.musculus	Hu_IGHV2-70*17	89.3	Mo_IGHV2-3*01	61.5	H1	13	H1-13-*	-1	TFSGFSLSTAGMS
A	heavy	Mus.musculus	Hu_IGHV2-70*17	89.3	Mo_IGHV2-3*01	33.3	H2	9	H2-9-1	12	DIWWDDKKH	BBBAALBBB
A	heavy	Mus.musculus	Hu_IGHV2-70*17	89.3	Hu_IGHV2-70*17	66.7	H3	12	H3-12-1	17	ARDMIFNFYFDV	BBBBAAALBBAB
A	heavy	Mus.musculus	Hu_IGHV2-70*17	89.3	Hu_IGHV2-70*17	100.0	H4	8	H4-8-1	10	KDTSKNQV	BBAAALBB
B	kappa	Mus.musculus	Hu_IGKV1-5*03	100.0	Mo_IGKV4-59*01	80.0	L1	10	L1-10-1	7	SASSRVGYMH	BBABBBABBB
B	kappa	Mus.musculus	Hu_IGKV1-5*03	100.0	Mo_IGKV4-59*01	100.0	L2	8	L2-8-1	5	YDTSKLAS	BLLABBBB
B	kappa	Mus.musculus	Hu_IGKV1-5*03	100.0	Hu_IGKV1-5*03	28.6	L3	9	L3-9-cis7-1	10	FQGSGYPFT	BBAABBbBB
B	kappa	Mus.musculus	Hu_IGKV1-5*03	100.0	Hu_IGKV1-5*03	100.0	L4	6	L4-6-1	5	GSGTEF	EBEABB
H	heavy	Mus.musculus	Hu_IGHV2-70*17	89.3	Mo_IGHV2-3*01	61.5	H1	13	H1-13-*	-1	TFSGFSLSTAGMS
H	heavy	Mus.musculus	Hu_IGHV2-70*17	89.3	Mo_IGHV2-3*01	33.3	H2	9	H2-9-1	12	DIWWDDKKH	BBBAALBBB
H	heavy	Mus.musculus	Hu_IGHV2-70*17	89.3	Hu_IGHV2-70*17	66.7	H3	12	H3-12-1	18	ARDMIFNFYFDV	BBBBAAALBBAB
H	heavy	Mus.musculus	Hu_IGHV2-70*17	89.3	Hu_IGHV2-70*17	100.0	H4	8	H4-8-1	10	KDTSKNQV	BBAAALBB
L	kappa	Mus.musculus	Hu_IGKV1-5*03	100.0	Mo_IGKV4-59*01	80.0	L1	10	L1-10-1	6	SASSRVGYMH	BBABBBABBB
L	kappa	Mus.musculus	Hu_IGKV1-5*03	100.0	Mo_IGKV4-59*01	100.0	L2	8	L2-8-1	6	YDTSKLAS	BLLABBBB
L	kappa	Mus.musculus	Hu_IGKV1-5*03	100.0	Hu_IGKV1-5*03	28.6	L3	9	L3-9-cis7-1	8	FQGSGYPFT	BBAABBbBB
L	kappa	Mus.musculus	Hu_IGKV1-5*03	100.0	Hu_IGKV1-5*03	100.0	L4	6	L4-6-1	6	GSGTEF	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022