PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 3PIQ

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	heavy	Homo.sapiens	Hu_IGHV3-43*01	93.2	Hu_IGHV3-43*01	76.9	H1	13	H1-13-1	10	TASGFSFDDSTMH	BBBLBBAAABBBB
A	heavy	Homo.sapiens	Hu_IGHV3-43*01	93.2	Hu_IGHV3-43*01	80.0	H2	10	H2-10-2	21	LISWNGGRTY	BBBAALABBB
A	heavy	Homo.sapiens	Hu_IGHV3-43*01	93.2	Hu_IGHV3-43*01	100.0	H3	23	H3-23-*	-1	AKDKGdsdydynlgysYFYYMDG
A	heavy	Homo.sapiens	Hu_IGHV3-43*01	93.2	Hu_IGHV3-43*01	100.0	H4	8	H4-8-1	13	RDNSKNSL	BBAAALBB
B	lambda	Homo.sapiens	Hu_IGLV3-21*01	98.5	Hu_IGLV3-21*01	72.7	L1	11	L1-11-3	14	GGNNIANKNVH	BBBLAAABBBB
B	lambda	Homo.sapiens	Hu_IGLV3-21*01	98.5	Hu_IGLV3-21*01	87.5	L2	8	L2-8-1	14	YYDDDRPS	BLLABBBB
B	lambda	Homo.sapiens	Hu_IGLV3-21*01	98.5	Hu_IGLV3-21*01	88.9	L3	11	L3-11-1	20	QVWDSNSDHVV	BBBBAAALBBB
B	lambda	Homo.sapiens	Hu_IGLV3-21*01	98.5	Hu_IGLV3-21*01	100.0	L4	6	L4-6-2	21	NSGNTA	BBEABB
C	heavy	Homo.sapiens	Hu_IGHV3-43*01	93.2	Hu_IGHV3-43*01	76.9	H1	13	H1-13-1	17	TASGFSFDDSTMH	BBBLBBAAABBBB
C	heavy	Homo.sapiens	Hu_IGHV3-43*01	93.2	Hu_IGHV3-43*01	80.0	H2	10	H2-10-2	21	LISWNGGRTY	BBBAALABBB
C	heavy	Homo.sapiens	Hu_IGHV3-43*01	93.2	Hu_IGHV3-43*01	100.0	H3	23	H3-23-*	-1	AKDKGdsdydynlgYSYFYYMDG
C	heavy	Homo.sapiens	Hu_IGHV3-43*01	93.2	Hu_IGHV3-43*01	100.0	H4	8	H4-8-1	16	RDNSKNSL	BBAAALBB
D	lambda	Homo.sapiens	Hu_IGLV3-21*01	98.5	Hu_IGLV3-21*01	72.7	L1	11	L1-11-3	21	GGNNIANKNVH	BBBLAAABBBB
D	lambda	Homo.sapiens	Hu_IGLV3-21*01	98.5	Hu_IGLV3-21*01	87.5	L2	8	L2-8-1	19	YYDDDRPS	BLEABBBB
D	lambda	Homo.sapiens	Hu_IGLV3-21*01	98.5	Hu_IGLV3-21*01	88.9	L3	11	L3-11-1	21	QVWDSNSDHVV	BBBBAAALBBB
D	lambda	Homo.sapiens	Hu_IGLV3-21*01	98.5	Hu_IGLV3-21*01	100.0	L4	6	L4-6-2	21	NSGNTA	BBEABB
E	heavy	Homo.sapiens	Hu_IGHV3-43*01	93.2	Hu_IGHV3-43*01	76.9	H1	13	H1-13-1	9	TASGFSFDDSTMH	BBBLBBAAABBBB
E	heavy	Homo.sapiens	Hu_IGHV3-43*01	93.2	Hu_IGHV3-43*01	80.0	H2	10	H2-10-2	13	LISWNGGRTY	BBBAALABBB
E	heavy	Homo.sapiens	Hu_IGHV3-43*01	93.2	Hu_IGHV3-43*01	100.0	H3	23	H3-23-*	-1	AKDKGdsdydynlgysYFYYMDG
E	heavy	Homo.sapiens	Hu_IGHV3-43*01	93.2	Hu_IGHV3-43*01	100.0	H4	8	H4-8-1	12	RDNSKNSL	BBAAALBB
F	lambda	Homo.sapiens	Hu_IGLV3-21*01	98.5	Hu_IGLV3-21*01	72.7	L1	11	L1-11-3	13	GGNNIANKNVH	BBBLAAABBBB
F	lambda	Homo.sapiens	Hu_IGLV3-21*01	98.5	Hu_IGLV3-21*01	87.5	L2	8	L2-8-1	15	YYDDDRPS	BLLABBBB
F	lambda	Homo.sapiens	Hu_IGLV3-21*01	98.5	Hu_IGLV3-21*01	88.9	L3	11	L3-11-1	18	QVWDSNSDHVV	BBBBAAALBBB
F	lambda	Homo.sapiens	Hu_IGLV3-21*01	98.5	Hu_IGLV3-21*01	100.0	L4	6	L4-6-2	22	NSGNTA	BBEABB
G	heavy	Homo.sapiens	Hu_IGHV3-43*01	93.2	Hu_IGHV3-43*01	76.9	H1	13	H1-13-1	21	TASGFSFDDSTMH	BBBLBBAAABBBB
G	heavy	Homo.sapiens	Hu_IGHV3-43*01	93.2	Hu_IGHV3-43*01	80.0	H2	10	H2-10-2	17	LISWNGGRTY	BBBAALABBB
G	heavy	Homo.sapiens	Hu_IGHV3-43*01	93.2	Hu_IGHV3-43*01	100.0	H3	23	H3-23-*	-1	AKDKGdsdydynlgYSYFYYMDG
G	heavy	Homo.sapiens	Hu_IGHV3-43*01	93.2	Hu_IGHV3-43*01	100.0	H4	8	H4-8-1	12	RDNSKNSL	BBAAALBB
H	heavy	Homo.sapiens	Hu_IGHV3-43*01	93.2	Hu_IGHV3-43*01	76.9	H1	13	H1-13-1	12	TASGFSFDDSTMH	BBELBBAAABBBB
H	heavy	Homo.sapiens	Hu_IGHV3-43*01	93.2	Hu_IGHV3-43*01	80.0	H2	10	H2-10-2	21	LISWNGGRTY	BBBAALABBB
H	heavy	Homo.sapiens	Hu_IGHV3-43*01	93.2	Hu_IGHV3-43*01	100.0	H3	23	H3-23-*	-1	AKDKGdsdydynlgYSYFYYMDG
H	heavy	Homo.sapiens	Hu_IGHV3-43*01	93.2	Hu_IGHV3-43*01	100.0	H4	8	H4-8-1	11	RDNSKNSL	BBAAALBB
I	lambda	Homo.sapiens	Hu_IGLV3-21*01	98.5	Hu_IGLV3-21*01	72.7	L1	11	L1-11-3	13	GGNNIANKNVH	BEBLAAABBBB
I	lambda	Homo.sapiens	Hu_IGLV3-21*01	98.5	Hu_IGLV3-21*01	87.5	L2	8	L2-8-1	21	YYDDDRPS	BLLABBBB
I	lambda	Homo.sapiens	Hu_IGLV3-21*01	98.5	Hu_IGLV3-21*01	88.9	L3	11	L3-11-1	26	QVWDSNSDHVV	BBBBAAALBBB
I	lambda	Homo.sapiens	Hu_IGLV3-21*01	98.5	Hu_IGLV3-21*01	100.0	L4	6	L4-6-2	23	NSGNTA	BBEABB
J	heavy	Homo.sapiens	Hu_IGHV3-43*01	93.2	Hu_IGHV3-43*01	76.9	H1	13	H1-13-1	17	TASGFSFDDSTMH	BBBLBBAAABBBB
J	heavy	Homo.sapiens	Hu_IGHV3-43*01	93.2	Hu_IGHV3-43*01	80.0	H2	10	H2-10-2	19	LISWNGGRTY	BBBAALABBB
J	heavy	Homo.sapiens	Hu_IGHV3-43*01	93.2	Hu_IGHV3-43*01	100.0	H3	23	H3-23-*	-1	AKDKGdsdydynlgYSYFYYMDG
J	heavy	Homo.sapiens	Hu_IGHV3-43*01	93.2	Hu_IGHV3-43*01	100.0	H4	8	H4-8-1	12	RDNSKNSL	BBAAALBB
K	lambda	Homo.sapiens	Hu_IGLV3-21*01	98.5	Hu_IGLV3-21*01	72.7	L1	11	L1-11-3	16	GGNNIANKNVH	BBBLAAABBBB
K	lambda	Homo.sapiens	Hu_IGLV3-21*01	98.5	Hu_IGLV3-21*01	87.5	L2	8	L2-8-1	24	YYDDDRPS	BLEABBBB
K	lambda	Homo.sapiens	Hu_IGLV3-21*01	98.5	Hu_IGLV3-21*01	88.9	L3	11	L3-11-1	19	QVWDSNSDHVV	BBBBAAALBBB
K	lambda	Homo.sapiens	Hu_IGLV3-21*01	98.5	Hu_IGLV3-21*01	100.0	L4	6	L4-6-2	22	NSGNTA	BBEABB
L	lambda	Homo.sapiens	Hu_IGLV3-21*01	98.5	Hu_IGLV3-21*01	72.7	L1	11	L1-11-3	13	GGNNIANKNVH	BBBLAAABBBB
L	lambda	Homo.sapiens	Hu_IGLV3-21*01	98.5	Hu_IGLV3-21*01	87.5	L2	8	L2-8-1	23	YYDDDRPS	BLEABBBB
L	lambda	Homo.sapiens	Hu_IGLV3-21*01	98.5	Hu_IGLV3-21*01	88.9	L3	11	L3-11-1	24	QVWDSNSDHVV	BBBBAAALBBB
L	lambda	Homo.sapiens	Hu_IGLV3-21*01	98.5	Hu_IGLV3-21*01	100.0	L4	6	L4-6-2	22	NSGNTA	BBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022