PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 3MLZ

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
H	heavy	Homo.sapiens	Hu_IGHV4-59*04	94.5	Hu_IGHV4-59*04	76.9	H1	13	H1-13-4	12	TVSGGSISGFHWS	BBBLBBABLBBBB
H	heavy	Homo.sapiens	Hu_IGHV4-59*04	94.5	Hu_IGHV4-59*04	88.9	H2	9	H2-9-1	12	YIYYSGSTS	BBBAALBBB
H	heavy	Homo.sapiens	Hu_IGHV4-59*04	94.5	Hu_IGHV4-59*04	100.0	H3	21	H3-21-*	-1	ARDFGEYHYdgrgfqcEGFDL
H	heavy	Homo.sapiens	Hu_IGHV4-59*04	94.5	Hu_IGHV4-59*04	87.5	H4	8	H4-8-1	13	VDTSRNQF	BBAAALBB
L	lambda	Homo.sapiens	Hu_IGLV1-51*02	94.1	Hu_IGLV1-51*02	92.3	L1	13	L1-13-1	14	SGSSSNIGNNMVS	BBBAAAAAABBBB
L	lambda	Homo.sapiens	Hu_IGLV1-51*02	94.1	Hu_IGLV1-51*02	87.5	L2	8	L2-8-1	16	YENSKRPS	BLLABBBB
L	lambda	Homo.sapiens	Hu_IGLV1-51*02	94.1	Hu_IGLV1-51*02	55.6	L3	10	L3-10-1	18	ATWDGSLRTV	BBBBAALBBB
L	lambda	Homo.sapiens	Hu_IGLV1-51*02	94.1	Hu_IGLV1-51*02	83.3	L4	6	L4-6-2	15	RSGTSA	BBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022