PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 3MAC

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
H	heavy	Homo.sapiens	Hu_IGHV1-69*15	100.0	Hu_IGHV1-69*15	84.6	H1	13	H1-13-1	15	KASGGTFNSYAFS	BBBLBBAAABBBB
H	heavy	Homo.sapiens	Hu_IGHV1-69*15	100.0	Hu_IGHV1-69*15	50.0	H2	10	H2-10-1	15	SIIPLFGFVV	BBBAAALBBB
H	heavy	Homo.sapiens	Hu_IGHV1-69*15	100.0	Hu_IGHV1-69*15	100.0	H3	14	H3-14-*	-1	ARYFDTYNNYGFAN	BBBLABAABABBAB
H	heavy	Homo.sapiens	Hu_IGHV1-69*15	100.0	Hu_IGHV1-69*15	100.0	H4	8	H4-8-1	9	ADESTSTA	BBAAALBB
L	lambda	Homo.sapiens	Hu_IGLV3-25*02	90.9	Hu_IGLV3-25*02	54.5	L1	11	L1-11-*	-1	SGDNIPYEYAS	BBABBBBLABB
L	lambda	Homo.sapiens	Hu_IGLV3-25*02	90.9	Hu_IGLV3-25*02	62.5	L2	8	L2-8-4	14	YGDNNRPS	BEAABBBB
L	lambda	Homo.sapiens	Hu_IGLV3-25*02	90.9	Hu_IGLV3-25*02	33.3	L3	11	L3-11-1	21	ASWDSMTVDGV	BBBBAAALBBB
L	lambda	Homo.sapiens	Hu_IGLV3-25*02	90.9	Hu_IGLV3-25*02	50.0	L4	6	L4-6-*	-1	NSGNTA	BALABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022