PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 3LH2

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
H	heavy	Homo.sapiens	Hu_IGHV1-69*10	86.3	Hu_IGHV1-69*10	76.9	H1	13	H1-13-*	-1	KASGGSFSTYALS	BBBEEBAAABBBB
H	heavy	Homo.sapiens	Hu_IGHV1-69*10	86.3	Hu_IGHV1-69*10	60.0	H2	10	H2-10-1	17	GVIPLLTITN	BBBAAALBBB
H	heavy	Homo.sapiens	Hu_IGHV1-69*10	86.3	Hu_IGHV1-69*10	100.0	H3	20	H3-20-*	-1	AREGTTgagwlgkpigAFAH
H	heavy	Homo.sapiens	Hu_IGHV1-69*10	86.3	Hu_IGHV1-69*10	87.5	H4	8	H4-8-1	10	ADRSTSTA	BBAAALBB
I	heavy	Homo.sapiens	Hu_IGHV1-69*10	86.3	Hu_IGHV1-69*10	76.9	H1	13	H1-13-*	-1	KASGGSFSTYALS	BBBEEBAAABBBB
I	heavy	Homo.sapiens	Hu_IGHV1-69*10	86.3	Hu_IGHV1-69*10	60.0	H2	10	H2-10-1	20	GVIPLLTITN	BBBAAALBBB
I	heavy	Homo.sapiens	Hu_IGHV1-69*10	86.3	Hu_IGHV1-69*10	100.0	H3	20	H3-20-*	-1	AREGTTgagwlgkpigAFAH
I	heavy	Homo.sapiens	Hu_IGHV1-69*10	86.3	Hu_IGHV1-69*10	87.5	H4	8	H4-8-1	9	ADRSTSTA	BBAAALBB
J	heavy	Homo.sapiens	Hu_IGHV1-69*10	86.3	Hu_IGHV1-69*10	76.9	H1	13	H1-13-*	-1	KASGGSFSTYALS	BBBEEBAAABBBB
J	heavy	Homo.sapiens	Hu_IGHV1-69*10	86.3	Hu_IGHV1-69*10	60.0	H2	10	H2-10-1	18	GVIPLLTITN	BBBAAALBBB
J	heavy	Homo.sapiens	Hu_IGHV1-69*10	86.3	Hu_IGHV1-69*10	100.0	H3	20	H3-20-*	-1	AREGTTGAGWlgkpigAFAH
J	heavy	Homo.sapiens	Hu_IGHV1-69*10	86.3	Hu_IGHV1-69*10	87.5	H4	8	H4-8-1	9	ADRSTSTA	BBAAALBB
K	heavy	Homo.sapiens	Hu_IGHV1-69*10	86.3	Hu_IGHV1-69*10	76.9	H1	13	H1-13-*	-1	KASGGSFSTYALS	BBBEEBAAABBBB
K	heavy	Homo.sapiens	Hu_IGHV1-69*10	86.3	Hu_IGHV1-69*10	60.0	H2	10	H2-10-1	17	GVIPLLTITN	BBBAAALBBB
K	heavy	Homo.sapiens	Hu_IGHV1-69*10	86.3	Hu_IGHV1-69*10	100.0	H3	20	H3-20-*	-1	AREGTTGAGWlgkpigAFAH
K	heavy	Homo.sapiens	Hu_IGHV1-69*10	86.3	Hu_IGHV1-69*10	87.5	H4	8	H4-8-1	7	ADRSTSTA	BBAAALBB
L	kappa	Homo.sapiens	Hu_IGKV3-20*01	94.2	Hu_IGKV3-20*01	66.7	L1	12	L1-12-2	6	RASQSVgNNKLA	BBABBBBLLBBB
L	kappa	Homo.sapiens	Hu_IGKV3-20*01	94.2	Hu_IGKV3-20*01	75.0	L2	8	L2-8-1	10	YGASSRPS	BLLABBBB
L	kappa	Homo.sapiens	Hu_IGKV3-20*01	94.2	Hu_IGKV3-20*01	71.4	L3	9	L3-9-2	16	QQYGQSLST	BBAABABBB
L	kappa	Homo.sapiens	Hu_IGKV3-20*01	94.2	Hu_IGKV3-20*01	100.0	L4	6	L4-6-1	6	GSGTDF	EBEABB
M	kappa	Homo.sapiens	Hu_IGKV3-20*01	94.2	Hu_IGKV3-20*01	66.7	L1	12	L1-12-2	7	RASQSVgNNKLA	BBABBBBLLBBB
M	kappa	Homo.sapiens	Hu_IGKV3-20*01	94.2	Hu_IGKV3-20*01	75.0	L2	8	L2-8-1	11	YGASSRPS	BLLABBBB
M	kappa	Homo.sapiens	Hu_IGKV3-20*01	94.2	Hu_IGKV3-20*01	71.4	L3	9	L3-9-2	21	QQYGQSLST	BBAABABBB
M	kappa	Homo.sapiens	Hu_IGKV3-20*01	94.2	Hu_IGKV3-20*01	100.0	L4	6	L4-6-1	8	GSGTDF	EBEABB
N	kappa	Homo.sapiens	Hu_IGKV3-20*01	94.2	Hu_IGKV3-20*01	66.7	L1	12	L1-12-2	8	RASQSVgNNKLA	BBABBBBLLBBB
N	kappa	Homo.sapiens	Hu_IGKV3-20*01	94.2	Hu_IGKV3-20*01	75.0	L2	8	L2-8-1	11	YGASSRPS	BLLABBBB
N	kappa	Homo.sapiens	Hu_IGKV3-20*01	94.2	Hu_IGKV3-20*01	71.4	L3	9	L3-9-2	16	QQYGQSLST	BBAABABBB
N	kappa	Homo.sapiens	Hu_IGKV3-20*01	94.2	Hu_IGKV3-20*01	100.0	L4	6	L4-6-1	8	GSGTDF	EBEABB
O	kappa	Homo.sapiens	Hu_IGKV3-20*01	94.2	Hu_IGKV3-20*01	66.7	L1	12	L1-12-2	8	RASQSVgNNKLA	BBABBBBLLBBB
O	kappa	Homo.sapiens	Hu_IGKV3-20*01	94.2	Hu_IGKV3-20*01	75.0	L2	8	L2-8-1	11	YGASSRPS	BLLABBBB
O	kappa	Homo.sapiens	Hu_IGKV3-20*01	94.2	Hu_IGKV3-20*01	71.4	L3	9	L3-9-2	17	QQYGQSLST	BBAABABBB
O	kappa	Homo.sapiens	Hu_IGKV3-20*01	94.2	Hu_IGKV3-20*01	100.0	L4	6	L4-6-1	6	GSGTDF	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022