PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 3I2C

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
H	heavy	Mus.musculus	Mo_IGHV10-3*01	90.4	Mo_IGHV10-3*01	92.3	H1	13	H1-13-1	11	AASGFNFNTYAMH	BBBLBBAAABBBB
H	heavy	Mus.musculus	Mo_IGHV10-3*01	90.4	Mo_IGHV10-3*01	83.3	H2	12	H2-12-1	8	RIRSKSHnyATD	BBBBAAALLBBB
H	heavy	Mus.musculus	Mo_IGHV10-3*01	90.4	Mo_IGHV10-3*01	50.0	H3	11	H3-11-*	-1	MREGIYGSFAY	BBBBABLBBAB
H	heavy	Mus.musculus	Mo_IGHV10-3*01	90.4	Mo_IGHV10-3*01	75.0	H4	8	H4-8-1	11	RDDSQGLL	BBAAALBB
L	kappa	Mus.musculus	Mo_IGKV3-12*01	98.6	Mo_IGKV3-12*01	73.3	L1	15	L1-15-*	-1	RASKSVSSsaysFFH	BBBBBABABALBBBB
L	kappa	Mus.musculus	Mo_IGKV3-12*01	98.6	Mo_IGKV3-12*01	87.5	L2	8	L2-8-1	13	YLASNLQS	BLLABBBB
L	kappa	Mus.musculus	Mo_IGKV3-12*01	98.6	Mo_IGKV3-12*01	85.7	L3	9	L3-9-cis7-1	24	QHSGELPFT	BBABBBbBB
L	kappa	Mus.musculus	Mo_IGKV3-12*01	98.6	Mo_IGKV3-12*01	100.0	L4	6	L4-6-1	15	GSGTDF	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022