PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 3BQU

#CDRs = 8; #Clusters = 13.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	kappa	Homo.sapiens	Hu_IGKV1D-13*01	86.8	Hu_IGKV1D-13*01	81.8	L1	11	L1-11-1	11	RASQGVTSALA	BBABBAEABBB
A	kappa	Homo.sapiens	Hu_IGKV1D-13*01	86.8	Hu_IGKV1D-13*01	100.0	L2	8	L2-8-1	17	YDASSLES	BLEABBBB
A	kappa	Homo.sapiens	Hu_IGKV1D-13*01	86.8	Hu_IGKV1D-13*01	57.1	L3	9	L3-9-cis7-1	25	QQLHFYPHT	BBAABBbBB
A	kappa	Homo.sapiens	Hu_IGKV1D-13*01	86.8	Hu_IGKV1D-13*01	83.3	L4	6	L4-6-1	18	GSGTEF	EBEABB
B	heavy	Homo.sapiens	Hu_IGHV2-5*02	88.9	Hu_IGHV2-5*02	80.0	H1	15	H1-15-1	13	SFSGFSLSDFGvgVG	BBBLBBAABBLBBBB
B	heavy	Homo.sapiens	Hu_IGHV2-5*02	88.9	Hu_IGHV2-5*02	77.8	H2	9	H2-9-1	15	IIYSDDDKR	BBBAALBBB
B	heavy	Homo.sapiens	Hu_IGHV2-5*02	88.9	Hu_IGHV2-5*02	100.0	H3	24	H3-24-*	-1	AHRRGPTTlfgvpiargpVNAMDV
B	heavy	Homo.sapiens	Hu_IGHV2-5*02	88.9	Hu_IGHV2-5*02	100.0	H4	8	H4-8-1	21	KDTSKNQV	BBAAALBB
C	kappa	Mus.musculus	Mo_IGKV17-121*01	97.0	Mo_IGKV17-121*01	100.0	L1	11	L1-11-*	-1	ITSTDIDDDMN	BBABBBBABBB
C	kappa	Mus.musculus	Mo_IGKV17-121*01	97.0	Mo_IGKV17-121*01	87.5	L2	8	L2-8-*	-1	SDGNTLRP	BBLLBBBB
C	kappa	Mus.musculus	Mo_IGKV17-121*01	97.0	Mo_IGKV17-121*01	100.0	L3	9	L3-9-cis7-1	17	LQSDNLPYT	BBAABBbBB
C	kappa	Mus.musculus	Mo_IGKV17-121*01	97.0	Mo_IGKV17-121*01	100.0	L4	6	L4-6-1	14	GYGTDF	EBEABB
D	heavy	Mus.musculus	Mo_IGHV1S45*01	90.3	Mo_IGHV1S45*01	84.6	H1	13	H1-13-1	14	KASGYSFTDYFMH	BBBLBBAAABBBB
D	heavy	Mus.musculus	Mo_IGHV1S45*01	90.3	Mo_IGHV1S45*01	50.0	H2	10	H2-10-*	-1	YINCYTGATN	BBALAALBBB
D	heavy	Mus.musculus	Mo_IGHV1S45*01	90.3	Mo_IGHV1S45*01	100.0	H3	15	H3-15-*	-1	ARTSIGYgSSPPFPY
D	heavy	Mus.musculus	Mo_IGHV1S45*01	90.3	Mo_IGHV1S45*01	75.0	H4	8	H4-8-1	7	VDTSSNTA	BBAAALBB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022