PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 2ZNX

#CDRs = 8; #Clusters = 9.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	heavy	Synthetic.construct	Mo_IGHV3S1*01	94.4	Mo_IGHV3S1*01	92.3	H1	13	H1-13-*	-1	SVTGDSITSDYWS
A	heavy	Synthetic.construct	Mo_IGHV3S1*01	94.4	Mo_IGHV3S1*01	88.9	H2	9	H2-9-1	8	YVSYSGSTY	BBBAALBBB
A	heavy	Synthetic.construct	Mo_IGHV3S1*01	94.4	Mo_IGHV3S1*01	50.0	H3	7	H3-7-*	-1	ANWDGDY
A	heavy	Synthetic.construct	Mo_IGHV3S1*01	94.4	Mo_IGHV3S1*01	100.0	H4	8	H4-8-1	9	RDTSKNQY	BBAAALBB
A	kappa	Synthetic.construct	Mo_IGKV5-43*01	98.6	Mo_IGKV5-43*01	90.9	L1	11	L1-11-1	7	RASQSIGNNLH	BBABBAEABBB
A	kappa	Synthetic.construct	Mo_IGKV5-43*01	98.6	Mo_IGKV5-43*01	100.0	L2	8	L2-8-1	12	KYASQSIS	BLLABBBB
A	kappa	Synthetic.construct	Mo_IGKV5-43*01	98.6	Mo_IGKV5-43*01	100.0	L3	9	L3-9-*	-1	QQSNSWPYT
A	kappa	Synthetic.construct	Mo_IGKV5-43*01	98.6	Mo_IGKV5-43*01	100.0	L4	6	L4-6-1	6	GSGTDF	EBEABB
B	heavy	Synthetic.construct	Mo_IGHV3S1*01	94.4	Mo_IGHV3S1*01	92.3	H1	13	H1-13-*	-1	SVTGDSITSDYWS
B	heavy	Synthetic.construct	Mo_IGHV3S1*01	94.4	Mo_IGHV3S1*01	88.9	H2	9	H2-9-1	8	YVSYSGSTY	BBBAALBBB
B	heavy	Synthetic.construct	Mo_IGHV3S1*01	94.4	Mo_IGHV3S1*01	50.0	H3	7	H3-7-*	-1	ANWDGDY
B	heavy	Synthetic.construct	Mo_IGHV3S1*01	94.4	Mo_IGHV3S1*01	100.0	H4	8	H4-8-*	-1	RDTSKNQY	BBAAALBB
B	kappa	Synthetic.construct	Mo_IGKV5-43*01	98.6	Mo_IGKV5-43*01	90.9	L1	11	L1-11-1	5	RASQSIGNNLH	BBABBAEABBB
B	kappa	Synthetic.construct	Mo_IGKV5-43*01	98.6	Mo_IGKV5-43*01	100.0	L2	8	L2-8-1	13	KYASQSIS	BLLABBBB
B	kappa	Synthetic.construct	Mo_IGKV5-43*01	98.6	Mo_IGKV5-43*01	100.0	L3	9	L3-9-*	-1	QQSNSWPYT
B	kappa	Synthetic.construct	Mo_IGKV5-43*01	98.6	Mo_IGKV5-43*01	100.0	L4	6	L4-6-1	5	GSGTDF	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022