PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 2X7L

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	heavy	Synthetic.construct	Rb_IGHV1S69*01	87.1	Rb_IGHV1S69*01	53.8	H1	13	H1-13-*	-1	KVSGFSLSGFWLN	BBBLBABABBBBB
A	heavy	Synthetic.construct	Rb_IGHV1S69*01	87.1	CDRLenMismatch	-1.0	H2	10	H2-10-*	-1	AIYRGSGSEW	BBBAABABBB
A	heavy	Synthetic.construct	Rb_IGHV1S69*01	87.1	Rb_IGHV1S69*01	50.0	H3	12	H3-12-*	-1	AADTTDNGYFTI	BBBAALALBBAB
A	heavy	Synthetic.construct	Rb_IGHV1S69*01	87.1	Rb_IGHV1S69*01	83.3	H4	6	H4-6-*	-1	DTSTTV	BBABbB
B	kappa	Synthetic.construct	Rb_IGKV1S3*02	88.1	Rb_IGKV1S3*02	72.7	L1	11	L1-11-*	-1	QASQSISSWLS	BBABALBAABB
B	kappa	Synthetic.construct	Rb_IGKV1S3*02	88.1	Rb_IGKV1S3*02	75.0	L2	8	L2-8-1	11	YDASNLAS	BLLABBBB
B	kappa	Synthetic.construct	Rb_IGKV1S3*02	88.1	Rb_IGKV1S3*02	30.0	L3	12	L3-12-*	-1	LGgypAASYRTA
B	kappa	Synthetic.construct	Rb_IGKV1S3*02	88.1	Rb_IGKV1S3*02	100.0	L4	6	L4-6-1	32	GSGTEY	EBEABB
C	heavy	Synthetic.construct	Rb_IGHV1S69*01	87.1	Rb_IGHV1S69*01	53.8	H1	13	H1-13-*	-1	KVSGFSLSGFWLN	BBBLBABABBBBB
C	heavy	Synthetic.construct	Rb_IGHV1S69*01	87.1	CDRLenMismatch	-1.0	H2	10	H2-10-*	-1	AIYRGSGSEW	BBBAABABBB
C	heavy	Synthetic.construct	Rb_IGHV1S69*01	87.1	Rb_IGHV1S69*01	50.0	H3	12	H3-12-*	-1	AADTTDNGYFTI	BBBAALALBBAB
C	heavy	Synthetic.construct	Rb_IGHV1S69*01	87.1	Rb_IGHV1S69*01	83.3	H4	6	H4-6-*	-1	DTSTTV	BBABbB
D	kappa	Synthetic.construct	Rb_IGKV1S3*02	88.1	Rb_IGKV1S3*02	72.7	L1	11	L1-11-*	-1	QASQSISSWLS	BBABAEBAABB
D	kappa	Synthetic.construct	Rb_IGKV1S3*02	88.1	Rb_IGKV1S3*02	75.0	L2	8	L2-8-1	10	YDASNLAS	BLLABBBB
D	kappa	Synthetic.construct	Rb_IGKV1S3*02	88.1	Rb_IGKV1S3*02	30.0	L3	12	L3-12-*	-1	LGgypAASYRTA
D	kappa	Synthetic.construct	Rb_IGKV1S3*02	88.1	Rb_IGKV1S3*02	100.0	L4	6	L4-6-1	32	GSGTEY	EBEABB
E	heavy	Synthetic.construct	Rb_IGHV1S69*01	87.1	Rb_IGHV1S69*01	53.8	H1	13	H1-13-*	-1	KVSGFSLSGFWLN	BBBLBABABBBBB
E	heavy	Synthetic.construct	Rb_IGHV1S69*01	87.1	CDRLenMismatch	-1.0	H2	10	H2-10-*	-1	AIYRGSGSEW	BBBAABABBB
E	heavy	Synthetic.construct	Rb_IGHV1S69*01	87.1	Rb_IGHV1S69*01	50.0	H3	12	H3-12-*	-1	AADTTDNGYFTI	BBBAALALBBAB
E	heavy	Synthetic.construct	Rb_IGHV1S69*01	87.1	Rb_IGHV1S69*01	83.3	H4	6	H4-6-*	-1	DTSTTV	BBABbB
F	kappa	Synthetic.construct	Rb_IGKV1S3*02	88.1	Rb_IGKV1S3*02	72.7	L1	11	L1-11-*	-1	QASQSISSWLS	BBABAEBAABB
F	kappa	Synthetic.construct	Rb_IGKV1S3*02	88.1	Rb_IGKV1S3*02	75.0	L2	8	L2-8-1	10	YDASNLAS	BLLABBBB
F	kappa	Synthetic.construct	Rb_IGKV1S3*02	88.1	Rb_IGKV1S3*02	30.0	L3	12	L3-12-*	-1	LGgypAASYRTA
F	kappa	Synthetic.construct	Rb_IGKV1S3*02	88.1	Rb_IGKV1S3*02	100.0	L4	6	L4-6-1	32	GSGTEY	EBEABB
G	heavy	Synthetic.construct	Rb_IGHV1S69*01	87.1	Rb_IGHV1S69*01	53.8	H1	13	H1-13-*	-1	KVSGFSLSGFWLN	BBBLBABABBBBB
G	heavy	Synthetic.construct	Rb_IGHV1S69*01	87.1	CDRLenMismatch	-1.0	H2	10	H2-10-*	-1	AIYRGSGSEW	BBBAABABBB
G	heavy	Synthetic.construct	Rb_IGHV1S69*01	87.1	Rb_IGHV1S69*01	50.0	H3	12	H3-12-*	-1	AADTTDNGYFTI	BBBAALALBBAB
G	heavy	Synthetic.construct	Rb_IGHV1S69*01	87.1	Rb_IGHV1S69*01	83.3	H4	6	H4-6-*	-1	DTSTTV	BBABbB
H	heavy	Synthetic.construct	Rb_IGHV1S69*01	87.1	Rb_IGHV1S69*01	53.8	H1	13	H1-13-*	-1	KVSGFSLSGFWLN	BBBLBABABBBBB
H	heavy	Synthetic.construct	Rb_IGHV1S69*01	87.1	CDRLenMismatch	-1.0	H2	10	H2-10-*	-1	AIYRGSGSEW	BBBAABABBB
H	heavy	Synthetic.construct	Rb_IGHV1S69*01	87.1	Rb_IGHV1S69*01	50.0	H3	12	H3-12-*	-1	AADTTDNGYFTI	BBBAALALBBAB
H	heavy	Synthetic.construct	Rb_IGHV1S69*01	87.1	Rb_IGHV1S69*01	83.3	H4	6	H4-6-*	-1	DTSTTV	BBABbB
I	kappa	Synthetic.construct	Rb_IGKV1S3*02	88.1	Rb_IGKV1S3*02	72.7	L1	11	L1-11-*	-1	QASQSISSWLS	BBABAEBAABB
I	kappa	Synthetic.construct	Rb_IGKV1S3*02	88.1	Rb_IGKV1S3*02	75.0	L2	8	L2-8-1	10	YDASNLAS	BLLABBBB
I	kappa	Synthetic.construct	Rb_IGKV1S3*02	88.1	Rb_IGKV1S3*02	30.0	L3	12	L3-12-*	-1	LGgypAASYRTA
I	kappa	Synthetic.construct	Rb_IGKV1S3*02	88.1	Rb_IGKV1S3*02	100.0	L4	6	L4-6-1	32	GSGTEY	EBEABB
J	heavy	Synthetic.construct	Rb_IGHV1S69*01	87.1	Rb_IGHV1S69*01	53.8	H1	13	H1-13-*	-1	KVSGFSLSGFWLN	BBBLBABABBBBB
J	heavy	Synthetic.construct	Rb_IGHV1S69*01	87.1	CDRLenMismatch	-1.0	H2	10	H2-10-*	-1	AIYRGSGSEW	BBBAABABBB
J	heavy	Synthetic.construct	Rb_IGHV1S69*01	87.1	Rb_IGHV1S69*01	50.0	H3	12	H3-12-*	-1	AADTTDNGYFTI	BBBAALALBBAB
J	heavy	Synthetic.construct	Rb_IGHV1S69*01	87.1	Rb_IGHV1S69*01	83.3	H4	6	H4-6-*	-1	DTSTTV	BBABbB
K	kappa	Synthetic.construct	Rb_IGKV1S3*02	88.1	Rb_IGKV1S3*02	72.7	L1	11	L1-11-*	-1	QASQSISSWLS	BBABAEBAABB
K	kappa	Synthetic.construct	Rb_IGKV1S3*02	88.1	Rb_IGKV1S3*02	75.0	L2	8	L2-8-1	10	YDASNLAS	BLLABBBB
K	kappa	Synthetic.construct	Rb_IGKV1S3*02	88.1	Rb_IGKV1S3*02	30.0	L3	12	L3-12-*	-1	LGgypAASYRTA
K	kappa	Synthetic.construct	Rb_IGKV1S3*02	88.1	Rb_IGKV1S3*02	100.0	L4	6	L4-6-1	32	GSGTEY	EBEABB
L	kappa	Synthetic.construct	Rb_IGKV1S3*02	88.1	Rb_IGKV1S3*02	72.7	L1	11	L1-11-*	-1	QASQSISSWLS	BBABALBAABB
L	kappa	Synthetic.construct	Rb_IGKV1S3*02	88.1	Rb_IGKV1S3*02	75.0	L2	8	L2-8-1	10	YDASNLAS	BLLABBBB
L	kappa	Synthetic.construct	Rb_IGKV1S3*02	88.1	Rb_IGKV1S3*02	30.0	L3	12	L3-12-*	-1	LGgypAASYRTA
L	kappa	Synthetic.construct	Rb_IGKV1S3*02	88.1	Rb_IGKV1S3*02	100.0	L4	6	L4-6-1	32	GSGTEY	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022