PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 2V7H

#CDRs = 8; #Clusters = 10.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	kappa	Mus.musculus	Mo_IGKV10-96*01	98.6	Mo_IGKV10-96*01	90.9	L1	11	L1-11-2	14	RASQDINNYLN	BBAEBALLBBB
A	kappa	Mus.musculus	Mo_IGKV10-96*01	98.6	Mo_IGKV10-96*01	87.5	L2	8	L2-8-*	-1	YYTSNLHS	BELEEBBA
A	kappa	Mus.musculus	Mo_IGKV10-96*01	98.6	Mo_IGKV10-96*01	100.0	L3	9	L3-9-cis7-1	22	QQGNTLPRT	BBAABBbBB
A	kappa	Mus.musculus	Mo_IGKV10-96*01	98.6	Mo_IGKV10-96*01	100.0	L4	6	L4-6-1	25	GSGTDY	EBEABB
B	heavy	Mus.musculus	Mo_IGHV1-9*01	91.8	Mo_IGHV1-9*01	76.9	H1	13	H1-13-1	20	KATGYTFSNYWID	BBBLBBAAABBBB
B	heavy	Mus.musculus	Mo_IGHV1-9*01	91.8	Mo_IGHV1-9*01	100.0	H2	10	H2-10-*	-1	EILPGSGSTN	BBBAABAEEB
B	heavy	Mus.musculus	Mo_IGHV1-9*01	91.8	Mo_IGHV1-9*01	50.0	H3	12	H3-12-*	-1	TRRGYWAYDFDY	BBBBBEEBBBAB
B	heavy	Mus.musculus	Mo_IGHV1-9*01	91.8	Mo_IGHV1-9*01	100.0	H4	8	H4-8-*	-1	ADTSSNTA	BLAAALBB
H	heavy	Mus.musculus	Mo_IGHV1-9*01	91.8	Mo_IGHV1-9*01	76.9	H1	13	H1-13-1	15	KATGYTFSNYWID	BBBLBBAAABBBB
H	heavy	Mus.musculus	Mo_IGHV1-9*01	91.8	Mo_IGHV1-9*01	100.0	H2	10	H2-10-*	-1	EILPGSGSTN	BBBAAALBBB
H	heavy	Mus.musculus	Mo_IGHV1-9*01	91.8	Mo_IGHV1-9*01	50.0	H3	12	H3-12-*	-1	TRRGYWAYDFDY	BBBBBEBBBBAB
H	heavy	Mus.musculus	Mo_IGHV1-9*01	91.8	Mo_IGHV1-9*01	100.0	H4	8	H4-8-1	22	ADTSSNTA	BEAAALBB
L	kappa	Mus.musculus	Mo_IGKV10-96*01	98.6	Mo_IGKV10-96*01	90.9	L1	11	L1-11-2	14	RASQDINNYLN	BBAEBALLBBB
L	kappa	Mus.musculus	Mo_IGKV10-96*01	98.6	Mo_IGKV10-96*01	87.5	L2	8	L2-8-*	-1	YYTSNLHS	BLLELBBA
L	kappa	Mus.musculus	Mo_IGKV10-96*01	98.6	Mo_IGKV10-96*01	100.0	L3	9	L3-9-2	16	QQGNTLPRT	BBAABABBB
L	kappa	Mus.musculus	Mo_IGKV10-96*01	98.6	Mo_IGKV10-96*01	100.0	L4	6	L4-6-1	20	GSGTDY	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022