PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 2QAD

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
C	kappa	Homo.sapiens	Hu_IGKV1-5*03	95.7	Hu_IGKV1-5*03	90.9	L1	11	L1-11-1	16	RASQSISNWLA	BBABBAEABBB
C	kappa	Homo.sapiens	Hu_IGKV1-5*03	95.7	Hu_IGKV1-5*03	87.5	L2	8	L2-8-1	15	YKASSLKS	BLLABBBB
C	kappa	Homo.sapiens	Hu_IGKV1-5*03	95.7	Hu_IGKV1-5*03	42.9	L3	9	L3-9-cis7-1	24	QQHDSSPYT	BBAABBbBB
C	kappa	Homo.sapiens	Hu_IGKV1-5*03	95.7	Hu_IGKV1-5*03	100.0	L4	6	L4-6-1	16	GSGTEF	EBEABB
D	heavy	Homo.sapiens	Hu_IGHV1-69*17	93.2	Hu_IGHV1-69*17	84.6	H1	13	H1-13-*	-1	KASGGTFSNYAIN	BBABEBAAABBBB
D	heavy	Homo.sapiens	Hu_IGHV1-69*17	93.2	Hu_IGHV1-69*17	80.0	H2	10	H2-10-1	26	GIIPIFNIAH	BBBAAALBBB
D	heavy	Homo.sapiens	Hu_IGHV1-69*17	93.2	Hu_IGHV1-69*17	50.0	H3	23	H3-23-*	-1	ASPYpndyndyapEEGMSWYFDL
D	heavy	Homo.sapiens	Hu_IGHV1-69*17	93.2	Hu_IGHV1-69*17	87.5	H4	8	H4-8-1	12	ADESTSTA	BBAAALBB
G	kappa	Homo.sapiens	Hu_IGKV1-5*03	95.7	Hu_IGKV1-5*03	90.9	L1	11	L1-11-1	16	RASQSISNWLA	BBABBAEABBB
G	kappa	Homo.sapiens	Hu_IGKV1-5*03	95.7	Hu_IGKV1-5*03	87.5	L2	8	L2-8-1	15	YKASSLKS	BLLABBBB
G	kappa	Homo.sapiens	Hu_IGKV1-5*03	95.7	Hu_IGKV1-5*03	42.9	L3	9	L3-9-cis7-1	23	QQHDSSPYT	BBAABBbBB
G	kappa	Homo.sapiens	Hu_IGKV1-5*03	95.7	Hu_IGKV1-5*03	100.0	L4	6	L4-6-1	16	GSGTEF	EBEABB
H	heavy	Homo.sapiens	Hu_IGHV1-69*17	93.2	Hu_IGHV1-69*17	84.6	H1	13	H1-13-*	-1	KASGGTFSNYAIN	BBABEBAAABBBB
H	heavy	Homo.sapiens	Hu_IGHV1-69*17	93.2	Hu_IGHV1-69*17	80.0	H2	10	H2-10-1	27	GIIPIFNIAH	BBBAAALBBB
H	heavy	Homo.sapiens	Hu_IGHV1-69*17	93.2	Hu_IGHV1-69*17	50.0	H3	23	H3-23-*	-1	ASPYpndyndyapEEGMSWYFDL
H	heavy	Homo.sapiens	Hu_IGHV1-69*17	93.2	Hu_IGHV1-69*17	87.5	H4	8	H4-8-1	12	ADESTSTA	BBAAALBB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022