PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 2HWZ

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
H	heavy	Homo.sapiens.Mus.musculus	Hu_IGHV2-70*17	90.4	Ra_IGHV8-20*01	86.7	H1	15	H1-15-1	7	TFSGFSLSTSGMsvG	BBBLBBAABBLBBBB
H	heavy	Homo.sapiens.Mus.musculus	Hu_IGHV2-70*17	90.4	Ra_IGHV8-20*01	66.7	H2	9	H2-9-1	8	DIWWDDKKD	BBBAALBBB
H	heavy	Homo.sapiens.Mus.musculus	Hu_IGHV2-70*17	90.4	Hu_IGHV2-70*17	66.7	H3	12	H3-12-*	-1	ARSMITNWYFDV	BBBBBLABBLAB
H	heavy	Homo.sapiens.Mus.musculus	Hu_IGHV2-70*17	90.4	Hu_IGHV2-70*17	87.5	H4	8	H4-8-1	9	KDTSANQV	BBAAALBB
L	kappa	Homo.sapiens.Mus.musculus	Hu_IGKV1-5*03	98.6	Ra_IGKV4S12*01	50.0	L1	10	L1-10-1	11	KCQLSVGYMH	BBABBBABBB
L	kappa	Homo.sapiens.Mus.musculus	Hu_IGKV1-5*03	98.6	Ra_IGKV4S12*01	100.0	L2	8	L2-8-1	6	YDTSKLAS	BLLABBBB
L	kappa	Homo.sapiens.Mus.musculus	Hu_IGKV1-5*03	98.6	Hu_IGKV1-5*03	28.6	L3	9	L3-9-cis7-1	12	FQGSGYPFT	BBAABBbBB
L	kappa	Homo.sapiens.Mus.musculus	Hu_IGKV1-5*03	98.6	Hu_IGKV1-5*03	83.3	L4	6	L4-6-1	8	GSGTAF	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022