PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 2HT4

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
C	heavy	Rattus.norvegicus	Mo_IGHV4-1*02	94.4	Mo_IGHV4-1*02	92.3	H1	13	H1-13-4	18	AASGFDYSRYWMS	BBBLBBABLBBBB
C	heavy	Rattus.norvegicus	Mo_IGHV4-1*02	94.4	Mo_IGHV4-1*02	90.0	H2	10	H2-10-2	14	EINPVSSTIN	BBBAALABBB
C	heavy	Rattus.norvegicus	Mo_IGHV4-1*02	94.4	Mo_IGHV4-1*02	100.0	H3	14	H3-14-*	-1	ARLYYGYGYWYFDV	BBBBBAALBBBBAB
C	heavy	Rattus.norvegicus	Mo_IGHV4-1*02	94.4	Mo_IGHV4-1*02	87.5	H4	8	H4-8-1	8	RDNAKDTL	BBAAALBB
D	kappa	Mus.musculus	Mo_IGKV4-59*01	91.3	Mo_IGKV4-59*01	90.0	L1	10	L1-10-*	-1	SASSSVSYIH	BBABBBBLBB
D	kappa	Mus.musculus	Mo_IGKV4-59*01	91.3	Mo_IGKV4-59*01	87.5	L2	8	L2-8-1	18	YDTSKLTS	BLLABBBB
D	kappa	Mus.musculus	Mo_IGKV4-59*01	91.3	Mo_IGKV4-59*01	75.0	L3	9	L3-9-cis7-1	22	QQWSSHPQT	BBAABBbBB
D	kappa	Mus.musculus	Mo_IGKV4-59*01	91.3	Mo_IGKV4-59*01	100.0	L4	6	L4-6-1	16	GSGTSY	EBEABB
E	heavy	Rattus.norvegicus	Mo_IGHV4-1*02	94.4	Mo_IGHV4-1*02	92.3	H1	13	H1-13-4	14	AASGFDYSRYWMS	BBBLBBABLBBBB
E	heavy	Rattus.norvegicus	Mo_IGHV4-1*02	94.4	Mo_IGHV4-1*02	90.0	H2	10	H2-10-2	16	EINPVSSTIN	BBBAALABBB
E	heavy	Rattus.norvegicus	Mo_IGHV4-1*02	94.4	Mo_IGHV4-1*02	100.0	H3	14	H3-14-*	-1	ARLYYGYGYWYFDV	BBBBBAALBBBBAB
E	heavy	Rattus.norvegicus	Mo_IGHV4-1*02	94.4	Mo_IGHV4-1*02	87.5	H4	8	H4-8-1	8	RDNAKDTL	BBAAALBB
F	kappa	Mus.musculus	Mo_IGKV4-59*01	91.3	Mo_IGKV4-59*01	90.0	L1	10	L1-10-*	-1	SASSSVSYIH	BBABBBBLBB
F	kappa	Mus.musculus	Mo_IGKV4-59*01	91.3	Mo_IGKV4-59*01	87.5	L2	8	L2-8-1	10	YDTSKLTS	BLLABBBB
F	kappa	Mus.musculus	Mo_IGKV4-59*01	91.3	Mo_IGKV4-59*01	75.0	L3	9	L3-9-cis7-1	17	QQWSSHPQT	BBAABBbBB
F	kappa	Mus.musculus	Mo_IGKV4-59*01	91.3	Mo_IGKV4-59*01	100.0	L4	6	L4-6-1	12	GSGTSY	EEEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022