PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 2HFG

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
H	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Mo_IGHV1S56*01	53.8	H1	13	H1-13-1	11	AASGFTISSSSIH	BBBLBBAAABBBB
H	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Mo_IGHV1S56*01	40.0	H2	10	H2-10-1	10	WVLPSVGFTD	BBBAAALBBB
H	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	100.0	H3	18	H3-18-*	-1	ARRVCYNRlgvcAGGMDY
H	heavy	Homo.sapiens	Hu_IGHV3-66*01	94.5	Hu_IGHV3-66*01	62.5	H4	8	H4-8-1	6	ADTSKNTA	BBAAALBB
L	kappa	Homo.sapiens	Hu_IGKV1-6*01	100.0	Mo_IGKV6-17*01	90.9	L1	11	L1-11-1	6	RASQDVSTAVA	BBABBAEABBB
L	kappa	Homo.sapiens	Hu_IGKV1-6*01	100.0	Mo_IGKV6-17*01	62.5	L2	8	L2-8-1	7	YSASFLYS	BLEABBBB
L	kappa	Homo.sapiens	Hu_IGKV1-6*01	100.0	Hu_IGKV1-6*01	28.6	L3	9	L3-9-cis7-1	18	QQSQISPPT	BBAABBbBB
L	kappa	Homo.sapiens	Hu_IGKV1-6*01	100.0	Hu_IGKV1-6*01	100.0	L4	6	L4-6-1	8	GSGTDF	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022