PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 1Y18

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	lambda	Mus.musculus.Homo.sapiens	Mo_IGLV1*01	98.5	Mo_IGLV1*01	85.7	L1	14	L1-14-1	10	RSSSGAVTtSNYAT	BBAAEBBBAAALBB
A	lambda	Mus.musculus.Homo.sapiens	Mo_IGLV1*01	98.5	Mo_IGLV1*01	87.5	L2	8	L2-8-1	7	GGTNKRAP	BLLABBBB
A	lambda	Mus.musculus.Homo.sapiens	Mo_IGLV1*01	98.5	Mo_IGLV1*01	75.0	L3	9	L3-9-4	7	ALWNSNHLV	BBBBEABBB
A	lambda	Mus.musculus.Homo.sapiens	Mo_IGLV1*01	98.5	Mo_IGLV1*01	83.3	L4	6	L4-6-2	15	LIGDRA	BBEABB
B	heavy	Mus.musculus.Homo.sapiens	Mo_IGHV4-1*02	90.4	Mo_IGHV4-1*02	84.6	H1	13	H1-13-1	9	AASGFDFRRYWMT	BBBLBBAAABBBB
B	heavy	Mus.musculus.Homo.sapiens	Mo_IGHV4-1*02	90.4	Mo_IGHV4-1*02	80.0	H2	10	H2-10-2	15	DINPDSRTIN	BBBAALABBB
B	heavy	Mus.musculus.Homo.sapiens	Mo_IGHV4-1*02	90.4	Mo_IGHV4-1*02	50.0	H3	16	H3-16-*	-1	VRLDFdvYNHYYVLDY
B	heavy	Mus.musculus.Homo.sapiens	Mo_IGHV4-1*02	90.4	Mo_IGHV4-1*02	87.5	H4	8	H4-8-1	8	RDNAKNSL	BBAAALBB
C	lambda	Mus.musculus.Homo.sapiens	Mo_IGLV1*01	98.5	Mo_IGLV1*01	85.7	L1	14	L1-14-1	11	RSSSGAVTtSNYAT	BBAAEBBBAAALBB
C	lambda	Mus.musculus.Homo.sapiens	Mo_IGLV1*01	98.5	Mo_IGLV1*01	87.5	L2	8	L2-8-1	7	GGTNKRAP	BLLABBBB
C	lambda	Mus.musculus.Homo.sapiens	Mo_IGLV1*01	98.5	Mo_IGLV1*01	75.0	L3	9	L3-9-4	7	ALWNSNHLV	BBBBEABBB
C	lambda	Mus.musculus.Homo.sapiens	Mo_IGLV1*01	98.5	Mo_IGLV1*01	83.3	L4	6	L4-6-2	15	LIGDRA	BBEABB
D	heavy	Mus.musculus.Homo.sapiens	Mo_IGHV4-1*02	90.4	Mo_IGHV4-1*02	84.6	H1	13	H1-13-1	10	AASGFDFRRYWMT	BBBLBBAAABBBB
D	heavy	Mus.musculus.Homo.sapiens	Mo_IGHV4-1*02	90.4	Mo_IGHV4-1*02	80.0	H2	10	H2-10-2	15	DINPDSRTIN	BBBAALABBB
D	heavy	Mus.musculus.Homo.sapiens	Mo_IGHV4-1*02	90.4	Mo_IGHV4-1*02	50.0	H3	16	H3-16-*	-1	VRLDFdvYNHYYVLDY
D	heavy	Mus.musculus.Homo.sapiens	Mo_IGHV4-1*02	90.4	Mo_IGHV4-1*02	87.5	H4	8	H4-8-1	9	RDNAKNSL	BBAAALBB
E	lambda	Mus.musculus.Homo.sapiens	Mo_IGLV1*01	98.5	Mo_IGLV1*01	85.7	L1	14	L1-14-1	11	RSSSGAVTtSNYAT	BBAAEBBBAAALBB
E	lambda	Mus.musculus.Homo.sapiens	Mo_IGLV1*01	98.5	Mo_IGLV1*01	87.5	L2	8	L2-8-1	8	GGTNKRAP	BLEABBBB
E	lambda	Mus.musculus.Homo.sapiens	Mo_IGLV1*01	98.5	Mo_IGLV1*01	75.0	L3	9	L3-9-4	6	ALWNSNHLV	BBBBEABBB
E	lambda	Mus.musculus.Homo.sapiens	Mo_IGLV1*01	98.5	Mo_IGLV1*01	83.3	L4	6	L4-6-2	16	LIGDRA	BBEABB
F	heavy	Mus.musculus.Homo.sapiens	Mo_IGHV4-1*02	90.4	Mo_IGHV4-1*02	84.6	H1	13	H1-13-1	10	AASGFDFRRYWMT	BBBLBBAAABBBB
F	heavy	Mus.musculus.Homo.sapiens	Mo_IGHV4-1*02	90.4	Mo_IGHV4-1*02	80.0	H2	10	H2-10-2	14	DINPDSRTIN	BBBAALABBB
F	heavy	Mus.musculus.Homo.sapiens	Mo_IGHV4-1*02	90.4	Mo_IGHV4-1*02	50.0	H3	16	H3-16-*	-1	VRLDFdvYNHYYVLDY
F	heavy	Mus.musculus.Homo.sapiens	Mo_IGHV4-1*02	90.4	Mo_IGHV4-1*02	87.5	H4	8	H4-8-1	9	RDNAKNSL	BBAAALBB
H	heavy	Mus.musculus.Homo.sapiens	Mo_IGHV4-1*02	90.4	Mo_IGHV4-1*02	84.6	H1	13	H1-13-1	10	AASGFDFRRYWMT	BBBLBBAAABBBB
H	heavy	Mus.musculus.Homo.sapiens	Mo_IGHV4-1*02	90.4	Mo_IGHV4-1*02	80.0	H2	10	H2-10-2	14	DINPDSRTIN	BBBAALABBB
H	heavy	Mus.musculus.Homo.sapiens	Mo_IGHV4-1*02	90.4	Mo_IGHV4-1*02	50.0	H3	16	H3-16-*	-1	VRLDFdvYNHYYVLDY
H	heavy	Mus.musculus.Homo.sapiens	Mo_IGHV4-1*02	90.4	Mo_IGHV4-1*02	87.5	H4	8	H4-8-1	9	RDNAKNSL	BBAAALBB
L	lambda	Mus.musculus.Homo.sapiens	Mo_IGLV1*01	98.5	Mo_IGLV1*01	85.7	L1	14	L1-14-1	11	RSSSGAVTtSNYAT	BBAAEBBBAAALBB
L	lambda	Mus.musculus.Homo.sapiens	Mo_IGLV1*01	98.5	Mo_IGLV1*01	87.5	L2	8	L2-8-1	7	GGTNKRAP	BLEABBBB
L	lambda	Mus.musculus.Homo.sapiens	Mo_IGLV1*01	98.5	Mo_IGLV1*01	75.0	L3	9	L3-9-4	7	ALWNSNHLV	BBBBEABBB
L	lambda	Mus.musculus.Homo.sapiens	Mo_IGLV1*01	98.5	Mo_IGLV1*01	83.3	L4	6	L4-6-2	16	LIGDRA	BBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022