PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 1T2Q

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
H	heavy	Mus.musculus	Mo_IGHV2-2*01	97.1	Mo_IGHV2-2*01	100.0	H1	13	H1-13-1	13	TVSGFSLTSYGVH	BBBLBBAAABBBB
H	heavy	Mus.musculus	Mo_IGHV2-2*01	97.1	Mo_IGHV2-2*01	100.0	H2	9	H2-9-1	11	VIWSGGSTD	BBBAALBBB
H	heavy	Mus.musculus	Mo_IGHV2-2*01	97.1	Mo_IGHV2-2*01	100.0	H3	12	H3-12-*	-1	ARNRGYSYAMDS	BBBBEAALBBAB
H	heavy	Mus.musculus	Mo_IGHV2-2*01	97.1	Mo_IGHV2-2*01	100.0	H4	8	H4-8-1	8	KDNSKSQV	BBAAALBB
L	kappa	Mus.musculus	Mo_IGKV1-117*02	95.6	Mo_IGKV1-117*02	81.2	L1	16	L1-16-1	5	RSSQSLvhssgNTYLH	BBABBABBAALBBBBB
L	kappa	Mus.musculus	Mo_IGKV1-117*02	95.6	Mo_IGKV1-117*02	87.5	L2	8	L2-8-1	8	YKVSNRFS	BLEABBBB
L	kappa	Mus.musculus	Mo_IGKV1-117*02	95.6	Mo_IGKV1-117*02	100.0	L3	9	L3-9-cis7-1	10	FQGSHVPLT	BBAABBbBB
L	kappa	Mus.musculus	Mo_IGKV1-117*02	95.6	Mo_IGKV1-117*02	100.0	L4	6	L4-6-1	4	GSGTDF	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022