PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 1S78

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
C	kappa	Homo.sapiens	Hu_IGKV1-6*01	100.0	Mo_IGKV6-17*01	81.8	L1	11	L1-11-1	15	KASQDVSIGVA	BBABBAEAABB
C	kappa	Homo.sapiens	Hu_IGKV1-6*01	100.0	Mo_IGKV6-17*01	100.0	L2	8	L2-8-1	12	YSASYRYT	BLLABBBB
C	kappa	Homo.sapiens	Hu_IGKV1-6*01	100.0	Hu_IGKV1-6*01	57.1	L3	9	L3-9-cis7-1	9	QQYYIYPYT	BBAABBbBB
C	kappa	Homo.sapiens	Hu_IGKV1-6*01	100.0	Hu_IGKV1-6*01	100.0	L4	6	L4-6-1	17	GSGTDF	EBEABB
D	heavy	Mus.musculus	Hu_IGHV3-66*01	89.0	Mo_IGHV1-18*01	76.9	H1	13	H1-13-1	11	AASGFTFTDYTMD	BBBLBBAAABBBB
D	heavy	Mus.musculus	Hu_IGHV3-66*01	89.0	Mo_IGHV1-18*01	70.0	H2	10	H2-10-1	20	DVNPNSGGSI	BBBAAALBBB
D	heavy	Mus.musculus	Hu_IGHV3-66*01	89.0	Hu_IGHV3-66*01	100.0	H3	12	H3-12-*	-1	ARNLGPSFYFDY	BBBABABABBAB
D	heavy	Mus.musculus	Hu_IGHV3-66*01	89.0	Hu_IGHV3-66*01	75.0	H4	8	H4-8-1	15	VDRSKNTL	BBAAALBB
E	kappa	Homo.sapiens	Hu_IGKV1-6*01	100.0	Mo_IGKV6-17*01	81.8	L1	11	L1-11-1	12	KASQDVSIGVA	BBABBAEABBB
E	kappa	Homo.sapiens	Hu_IGKV1-6*01	100.0	Mo_IGKV6-17*01	100.0	L2	8	L2-8-1	9	YSASYRYT	BLLABBBB
E	kappa	Homo.sapiens	Hu_IGKV1-6*01	100.0	Hu_IGKV1-6*01	57.1	L3	9	L3-9-cis7-1	8	QQYYIYPYT	BBAABBbBB
E	kappa	Homo.sapiens	Hu_IGKV1-6*01	100.0	Hu_IGKV1-6*01	100.0	L4	6	L4-6-1	17	GSGTDF	EBEABB
F	heavy	Mus.musculus	Hu_IGHV3-66*01	89.0	Mo_IGHV1-18*01	76.9	H1	13	H1-13-1	13	AASGFTFTDYTMD	BBBLBBAAABBBB
F	heavy	Mus.musculus	Hu_IGHV3-66*01	89.0	Mo_IGHV1-18*01	70.0	H2	10	H2-10-1	17	DVNPNSGGSI	BBBAAALBBB
F	heavy	Mus.musculus	Hu_IGHV3-66*01	89.0	Hu_IGHV3-66*01	100.0	H3	12	H3-12-*	-1	ARNLGPSFYFDY	BBBBBABABBAB
F	heavy	Mus.musculus	Hu_IGHV3-66*01	89.0	Hu_IGHV3-66*01	75.0	H4	8	H4-8-1	10	VDRSKNTL	BBAAALBB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022