PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 1IGF

#CDRs = 8; #Clusters = 10.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
H	heavy	Mus.musculus	Mo_IGHV5-9-3*01	90.4	Mo_IGHV5-9-3*01	84.6	H1	13	H1-13-1	19	AASGFTFSRCAMS	BBBLBBAAABBBB
H	heavy	Mus.musculus	Mo_IGHV5-9-3*01	90.4	Mo_IGHV5-9-3*01	80.0	H2	10	H2-10-2	12	GISSGGSYTF	BBBAALABBB
H	heavy	Mus.musculus	Mo_IGHV5-9-3*01	90.4	Mo_IGHV5-9-3*01	50.0	H3	12	H3-12-*	-1	TRYSSDPFYFDY	BBBBABBABBAB
H	heavy	Mus.musculus	Mo_IGHV5-9-3*01	90.4	Mo_IGHV5-9-3*01	75.0	H4	8	H4-8-*	-1	RNNARNTL	BALAALBB
J	heavy	Mus.musculus	Mo_IGHV5-9-3*01	90.4	Mo_IGHV5-9-3*01	84.6	H1	13	H1-13-*	-1	AASGFTFSRCAMS	BBBLBBABABBBB
J	heavy	Mus.musculus	Mo_IGHV5-9-3*01	90.4	Mo_IGHV5-9-3*01	80.0	H2	10	H2-10-2	18	GISSGGSYTF	BBBAALABBB
J	heavy	Mus.musculus	Mo_IGHV5-9-3*01	90.4	Mo_IGHV5-9-3*01	50.0	H3	12	H3-12-*	-1	TRYSSDPFYFDY	BBBBABBABBAB
J	heavy	Mus.musculus	Mo_IGHV5-9-3*01	90.4	Mo_IGHV5-9-3*01	75.0	H4	8	H4-8-1	22	RNNARNTL	BBAAALBB
L	kappa	Mus.musculus	Mo_IGKV1-117*01	100.0	Mo_IGKV1-117*01	62.5	L1	16	L1-16-*	-1	RSNQTIllsdgDTYLE	BBABBABBAAEBBBBB
L	kappa	Mus.musculus	Mo_IGKV1-117*01	100.0	Mo_IGKV1-117*01	100.0	L2	8	L2-8-1	13	YKVSNRFS	BLLABBBB
L	kappa	Mus.musculus	Mo_IGKV1-117*01	100.0	Mo_IGKV1-117*01	100.0	L3	9	L3-9-cis7-1	18	FQGSHVPPT	BBAABBbBB
L	kappa	Mus.musculus	Mo_IGKV1-117*01	100.0	Mo_IGKV1-117*01	100.0	L4	6	L4-6-1	16	GSGTDF	EBEABB
M	kappa	Mus.musculus	Mo_IGKV1-117*01	100.0	Mo_IGKV1-117*01	62.5	L1	16	L1-16-*	-1	RSNQTIllsdgDTYLE	BBABBABBAABBEBBB
M	kappa	Mus.musculus	Mo_IGKV1-117*01	100.0	Mo_IGKV1-117*01	100.0	L2	8	L2-8-1	22	YKVSNRFS	BLLBBBBB
M	kappa	Mus.musculus	Mo_IGKV1-117*01	100.0	Mo_IGKV1-117*01	100.0	L3	9	L3-9-cis7-1	19	FQGSHVPPT	BBAABBbBB
M	kappa	Mus.musculus	Mo_IGKV1-117*01	100.0	Mo_IGKV1-117*01	100.0	L4	6	L4-6-1	11	GSGTDF	EBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022