PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 1CT8

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	kappa	Mus.musculus	Mo_IGKV5-43*01	92.6	Mo_IGKV5-43*01	81.8	L1	11	L1-11-1	6	RASQSVSNKLH	BBABBAEABBB
A	kappa	Mus.musculus	Mo_IGKV5-43*01	92.6	Mo_IGKV5-43*01	75.0	L2	8	L2-8-1	15	KFASQSIP	BLLABBBB
A	kappa	Mus.musculus	Mo_IGKV5-43*01	92.6	Mo_IGKV5-43*01	28.6	L3	9	L3-9-cis7-1	9	HQTHGRPLT	BBAABBbBB
A	kappa	Mus.musculus	Mo_IGKV5-43*01	92.6	Mo_IGKV5-43*01	83.3	L4	6	L4-6-1	5	GSGSDF	EBEABB
B	heavy	Mus.musculus	Mo_IGHV1S61*01	75.3	Mo_IGHV1S61*01	61.5	H1	13	H1-13-1	18	KTSGFTFSSSYIN	BBBLBBAAABBBB
B	heavy	Mus.musculus	Mo_IGHV1S61*01	75.3	Mo_IGHV1S61*01	50.0	H2	10	H2-10-1	7	WIYAGSGGTV	BBBAAALBBB
B	heavy	Mus.musculus	Mo_IGHV1S61*01	75.3	Mo_IGHV1S61*01	100.0	H3	11	H3-11-*	-1	ARYRYDEGFAY	BBBBAAAEBAB
B	heavy	Mus.musculus	Mo_IGHV1S61*01	75.3	Mo_IGHV1S61*01	100.0	H4	8	H4-8-1	6	VDTSSSTA	BBAAALBB
C	kappa	Mus.musculus	Mo_IGKV5-43*01	92.6	Mo_IGKV5-43*01	81.8	L1	11	L1-11-1	6	RASQSVSNKLH	BBABBAEABBB
C	kappa	Mus.musculus	Mo_IGKV5-43*01	92.6	Mo_IGKV5-43*01	75.0	L2	8	L2-8-1	12	KFASQSIP	BLLABBBB
C	kappa	Mus.musculus	Mo_IGKV5-43*01	92.6	Mo_IGKV5-43*01	28.6	L3	9	L3-9-cis7-1	10	HQTHGRPLT	BBAABBbBB
C	kappa	Mus.musculus	Mo_IGKV5-43*01	92.6	Mo_IGKV5-43*01	83.3	L4	6	L4-6-1	4	GSGSDF	EBEABB
D	heavy	Mus.musculus	Mo_IGHV1S61*01	75.3	Mo_IGHV1S61*01	61.5	H1	13	H1-13-1	16	KTSGFTFSSSYIN	BBBLBBAAABBBB
D	heavy	Mus.musculus	Mo_IGHV1S61*01	75.3	Mo_IGHV1S61*01	50.0	H2	10	H2-10-1	7	WIYAGSGGTV	BBBAAALBBB
D	heavy	Mus.musculus	Mo_IGHV1S61*01	75.3	Mo_IGHV1S61*01	100.0	H3	11	H3-11-*	-1	ARYRYDEGFAY	BBBBAAAEBAB
D	heavy	Mus.musculus	Mo_IGHV1S61*01	75.3	Mo_IGHV1S61*01	100.0	H4	8	H4-8-1	6	VDTSSSTA	BBAAALBB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022