PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 1AD0

#CDRs = 8; #Clusters = 9.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	kappa	Homo.sapiens	Hu_IGKV1-6*01	89.4	CDRLenMismatch	-1.0	L1	10	L1-10-1	9	RASSSVTYIH	BBABBBABBB
A	kappa	Homo.sapiens	Hu_IGKV1-6*01	89.4	Hu_IGKV1-6*01	62.5	L2	8	L2-8-1	4	YATSNLAS	BLLABBBB
A	kappa	Homo.sapiens	Hu_IGKV1-6*01	89.4	Hu_IGKV1-6*01	14.3	L3	9	L3-9-cis7-1	16	QHWSSKPPT	BBAABBbBB
A	kappa	Homo.sapiens	Hu_IGKV1-6*01	89.4	Hu_IGKV1-6*01	83.3	L4	6	L4-6-1	9	GSGTDY	EBEABB
B	heavy	Homo.sapiens	Hu_IGHV3-72*01	84.9	Hu_IGHV3-72*01	69.2	H1	13	H1-13-1	10	ATSGFTFTDYYMN	BBBLBBAAABBBB
B	heavy	Homo.sapiens	Hu_IGHV3-72*01	84.9	Hu_IGHV3-72*01	66.7	H2	12	H2-12-*	-1	FIGNkaNGYTTE	BBBBBAALLBBB
B	heavy	Homo.sapiens	Hu_IGHV3-72*01	84.9	Hu_IGHV3-72*01	50.0	H3	12	H3-12-*	-1	TRDRGLRFYFDY	BBBABBLABBAB
B	heavy	Homo.sapiens	Hu_IGHV3-72*01	84.9	Hu_IGHV3-72*01	62.5	H4	8	H4-8-1	7	RDKSKSTL	BBAAALBB
C	kappa	Homo.sapiens	Hu_IGKV1-6*01	89.4	CDRLenMismatch	-1.0	L1	10	L1-10-1	10	RASSSVTYIH	BBABBBABBB
C	kappa	Homo.sapiens	Hu_IGKV1-6*01	89.4	Hu_IGKV1-6*01	62.5	L2	8	L2-8-1	4	YATSNLAS	BLLABBBB
C	kappa	Homo.sapiens	Hu_IGKV1-6*01	89.4	Hu_IGKV1-6*01	14.3	L3	9	L3-9-cis7-1	16	QHWSSKPPT	BBAABBbBB
C	kappa	Homo.sapiens	Hu_IGKV1-6*01	89.4	Hu_IGKV1-6*01	83.3	L4	6	L4-6-1	9	GSGTDY	EBEABB
D	heavy	Homo.sapiens	Hu_IGHV3-72*01	84.9	Hu_IGHV3-72*01	69.2	H1	13	H1-13-1	10	ATSGFTFTDYYMN	BBBLBBAAABBBB
D	heavy	Homo.sapiens	Hu_IGHV3-72*01	84.9	Hu_IGHV3-72*01	66.7	H2	12	H2-12-1	11	FIGNkaNGYTTE	BBBBAAALLBBB
D	heavy	Homo.sapiens	Hu_IGHV3-72*01	84.9	Hu_IGHV3-72*01	50.0	H3	12	H3-12-*	-1	TRDRGLRFYFDY	BBBABBLABBAB
D	heavy	Homo.sapiens	Hu_IGHV3-72*01	84.9	Hu_IGHV3-72*01	62.5	H4	8	H4-8-1	7	RDKSKSTL	BBAAALBB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022