PyIgClassify2: Canonical Clusters of Antibody CDR Loop Conformations

PyIgClassify2: Classification of Antibody CDR Conformations

CDRs for query 4QCI

#CDRs = 8; #Clusters = 8.
Chain	Gene	PDB Species	Frame Germline	Frame %	CDR Germline	CDR %	CDR	Length	Cluster	Distance(°)	Sequence	Ramachandran
A	lambda	Homo.sapiens	Hu_IGLV3-1*01	92.5	Hu_IGLV3-1*01	45.5	L1	11	L1-11-3	6	SGDSLGSYFVH	BBBLAAABBBB
A	lambda	Homo.sapiens	Hu_IGLV3-1*01	92.5	Hu_IGLV3-1*01	75.0	L2	8	L2-8-1	6	YDDSNRPS	BLLABBBB
A	lambda	Homo.sapiens	Hu_IGLV3-1*01	92.5	Hu_IGLV3-1*01	12.5	L3	9	L3-9-*	-1	SAFTHNSDV	BBBBABABA
A	lambda	Homo.sapiens	Hu_IGLV3-1*01	92.5	Hu_IGLV3-1*01	100.0	L4	6	L4-6-2	15	NSGNTA	BBEABB
B	heavy	Homo.sapiens	Hu_IGHV3-23*04	100.0	Hu_IGHV3-23*04	100.0	H1	13	H1-13-1	6	AASGFTFSSYAMS	BBBLBBAAABBBB
B	heavy	Homo.sapiens	Hu_IGHV3-23*04	100.0	Hu_IGHV3-23*04	40.0	H2	10	H2-10-2	10	YISDDGSLKY	BBBAALABBB
B	heavy	Homo.sapiens	Hu_IGHV3-23*04	100.0	Hu_IGHV3-23*04	50.0	H3	13	H3-13-2	20	ARHPYWYGGQLDL	BBBABAABABBAB
B	heavy	Homo.sapiens	Hu_IGHV3-23*04	100.0	Hu_IGHV3-23*04	100.0	H4	8	H4-8-1	5	RDNSKNTL	BBAAALBB
H	heavy	Homo.sapiens	Hu_IGHV3-23*04	100.0	Hu_IGHV3-23*04	100.0	H1	13	H1-13-1	7	AASGFTFSSYAMS	BBBLBBAAABBBB
H	heavy	Homo.sapiens	Hu_IGHV3-23*04	100.0	Hu_IGHV3-23*04	40.0	H2	10	H2-10-2	10	YISDDGSLKY	BBBAALABBB
H	heavy	Homo.sapiens	Hu_IGHV3-23*04	100.0	Hu_IGHV3-23*04	50.0	H3	13	H3-13-2	20	ARHPYWYGGQLDL	BBBABAABABBAB
H	heavy	Homo.sapiens	Hu_IGHV3-23*04	100.0	Hu_IGHV3-23*04	100.0	H4	8	H4-8-1	5	RDNSKNTL	BBAAALBB
L	lambda	Homo.sapiens	Hu_IGLV3-1*01	92.5	Hu_IGLV3-1*01	45.5	L1	11	L1-11-3	6	SGDSLGSYFVH	BBBLAAABBBB
L	lambda	Homo.sapiens	Hu_IGLV3-1*01	92.5	Hu_IGLV3-1*01	75.0	L2	8	L2-8-1	6	YDDSNRPS	BLEABBBB
L	lambda	Homo.sapiens	Hu_IGLV3-1*01	92.5	Hu_IGLV3-1*01	12.5	L3	9	L3-9-*	-1	SAFTHNSDV	BBBBABABA
L	lambda	Homo.sapiens	Hu_IGLV3-1*01	92.5	Hu_IGLV3-1*01	100.0	L4	6	L4-6-2	13	NSGNTA	BBEABB

Site developed by the Antibody Team at the lab of Roland Dunbrack. Last updated on Oct. 13, 2022