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Clusters with M>=5,R_CF_UNPclus>=0.7 and diff Pfam Architecture
Click here for table column description
Pfam Architecture
Cluster ID
Symmetry
Stoichiometry
CF_clus
CF_arch
ENT_clus
UNP_clus
ENT_arch
UNP_arch
SeqID
R_CFs_UNPs
R_PDB
R_EPPIC
R_PISA
(Actin)(Gelsolin)
1
C1
AB
14
16
43
14
51
16
15
1.00
0.98
1.00
0.79
(Ald_Xan_dh_C)_(Ald_Xan_dh_C2)(FAD_binding_5)_(CO_deh_flav_C )(Fer2)_(Fer2_2)
1
C1
ABC
7
7
22
16
22
16
3
1.00
0.14
0.05
0.05
(Ald_Xan_dh_C)_(Ald_Xan_dh_C2)(FAD_binding_5)_(CO_deh_flav_C )(Fer2)_(Fer2_2)
4
C2
A2B2C2
6
7
21
13
22
16
3
1.00
0.95
1.00
1.00
(AMO)(AmoC)(Monooxygenase_B)
1
C1
ABC
11
11
12
7
12
7
3
1.00
0.08
0.33
0.75
(AMO)(AmoC)(Monooxygenase_B)
2
C1
ABC
11
11
12
7
12
7
6
1.00
0
0
0.75
(AMO)(AmoC)(Monooxygenase_B)
3
C1
ABC
10
11
11
7
12
7
3
0.90
0
0
0.73
(AMO)(AmoC)(Monooxygenase_B)
4
C1
ABC
9
11
9
6
12
7
72
0.81
0
0
0.89
(ANF_receptor)_(Lig_chan-Glu_bd)_(Lig_chan)(ANF_receptor)_(L ig_chan-Glu_bd)_(Lig_chan)_(CaM_bdg_C0)
1
C1
AB
10
16
10
3
16
4
69
1.00
0
0.30
1.00
(ANF_receptor)_(Lig_chan-Glu_bd)_(Lig_chan)(ANF_receptor)_(L ig_chan-Glu_bd)_(Lig_chan)_(CaM_bdg_C0)
2
C1
AB
10
16
10
3
16
4
69
1.00
0
0.20
1.00
(ANF_receptor)_(Lig_chan-Glu_bd)_(Lig_chan)_(CaM_bdg_C0)(ANF _receptor)_(Lig_chan-Glu_bd)_(Lig_chan)_(NMDAR2_C)
1
C1
AB
21
26
21
4
26
5
26
1.00
0
0.10
0.95
(Arena_glycoprot)(C1-set)(MHC_I)_(C1-set)
1
C1
ABC
7
7
20
8
20
8
0
1.00
1.00
0
0.80
(Asp_decarbox)(peptide)
1
C1
AB
7
7
17
6
17
6
0
1.00
0.06
1.00
0
(Asp_decarbox)(peptide)
2
C1
AB
7
7
16
6
17
6
6
1.00
0
0
0
(Asp_decarbox)(peptide)
6
C2
A2B2
7
7
16
6
17
6
5
1.00
0
0
0
(ATG8)(peptide)
1
C1
AB
36
36
44
17
45
17
0
1.00
0.84
0.89
0.57
(Avidin)(peptide)
2
C1
AB
7
10
41
1
50
2
12
1.00
0
0
0
(Avidin)(peptide)
1
C1
AB
8
10
39
2
50
2
13
0.88
0
0
0
(bCoV_S1_RBD)(Peptidase_M2)
1
C1
AB
10
10
19
6
19
6
10
1.00
0.95
0.05
0.95
(BH4)_(Bcl-2)(peptide)
1
C1
AB
38
41
43
7
46
7
0
1.00
0.60
0.47
0.53
(Bromodomain)(peptide)
1
C1
AB
32
58
44
13
96
21
0
0.71
0.89
0.45
0.91
(C1-set)(CoV_nucleocap)(MHC_I)_(C1-set)
1
C1
ABC
8
8
13
10
13
10
0
1.00
1.00
0
0.77
(C1-set)(Gag_p17)(MHC_I)_(C1-set)
1
C1
ABC
6
7
12
9
13
11
22
0.85
1.00
0
1.00
(C1-set)(GP120)(MHC_I)_(C1-set)
1
C1
ABC
7
7
12
11
12
11
0
1.00
1.00
0
0.83
(C1-set)(Hepatitis_core)(MHC_I)_(C1-set)
1
C1
ABC
5
5
6
6
6
6
0
1.00
1.00
0.50
1.00
(C1-set)(MHC_I)_(C1-set)
1
C1
AB
22
23
31
21
32
22
12
1.00
1.00
0.84
0.81
(C1-set)(MHC_I)_(C1-set)(RVT_1)
1
C1
ABC
10
12
12
13
16
17
0
1.00
1.00
0
1.00
(Cbl_N)_(Cbl_N2)_(Cbl_N3)(peptide)
1
C1
AB
7
11
15
2
22
4
0
0.87
0.93
0.53
0.67
(CCDC23)(Vasohibin)
1
C1
AB
15
15
18
4
18
4
14
1.00
1.00
0.94
0.78
(CDI)(Cyclin_N)_(Cyclin_C)(Pkinase)
1
C1
ABC
5
5
7
6
7
6
3
1.00
1.00
0.86
1.00
(Chromo)(Histone)
1
C1
AB
19
19
31
29
31
29
0
1.00
0.68
0.65
0.68
(CoV_NSP7)(CoV_NSP8)
8
C2
A2B2
6
7
10
4
11
5
3
1.00
0.50
0
0.80
(CRAL_TRIO_2)_(RhoGAP)(Ras)
1
C1
AB
5
5
5
3
7
3
52
1.00
1.00
1.00
1.00
(Cupin_8)(peptide)
1
C1
AB
6
7
25
1
30
2
12
1.00
0.24
0
0.08
(Cupin_8)(peptide)
2
C1
AB
6
7
25
1
30
2
12
1.00
0
0
0
(Cupin_8)(peptide)
4
C2
A2B2
6
7
25
1
30
2
7
1.00
0.84
0.92
0.92
(Cupin_8)(peptide)
5
C2
A2B2
6
7
25
1
30
2
12
1.00
0
0
0
(Cupin_8)(peptide)
6
C2
A2B2
6
7
25
1
30
2
12
1.00
0
0
0
(Cyclin_N)_(Cyclin_C)(Pkinase)(peptide)
1
C1
ABC
8
8
21
2
25
3
3
1.00
1.00
0.67
0.86
(DHR-2)(Ras)
1
C1
AB
8
11
10
7
14
9
11
1.00
0.60
0.30
0.20
(Dynein_light)(peptide)
4
C2
A2B2
12
13
23
5
24
5
0
0.92
0.87
0.52
0.91
(eIF_4EBP)(IF4E)
1
C1
AB
13
13
20
9
20
9
0
1.00
1.00
0.90
0.75
(ETF)(ETF)_(ETF_alpha)
1
C1
AB
7
7
12
10
12
10
24
1.00
1.00
1.00
1.00
(FAM181)(YBD)
1
C1
AB
10
11
20
8
22
9
23
1.00
1.00
1.00
0.60
(FAM181)(YBD)
2
C1
AB
5
11
15
3
22
9
80
0.71
0
0
0
(FAM181)(YBD)
6
C2
A2B2
10
11
20
8
22
9
23
1.00
0
0
0.10
(FAM181)(YBD)
7
C2
A2B2
5
11
15
3
22
9
0
0.71
0
0
0.27
(FAM181)(YBD)
8
C2
A2B2
5
11
15
3
22
9
80
0.71
0
0
0
(FKBP_C)(FRB_dom)
1
C1
AB
7
8
11
5
13
5
40
1.00
1.00
0
0.18
(HCV_NS1)(V-set)_(C1-set)(V-set_2)_(C1-set)
1
C1
ABC
6
11
6
3
11
7
21
1.00
1.00
0.33
1.00
(HCV_NS1)(V-set)_(C1-set)(V-set_2)_(C1-set)
2
C1
ABC
6
11
6
3
11
7
19
1.00
0
0
0
(HCV_NS4a)(Peptidase_S29)
1
C1
AB
7
7
46
18
46
18
9
1.00
0.52
1.00
0.28
(Histone)(Histone)_(Histone_H2A_C)(Linker_histone)(TAF)
1
C1
A4B2CD2
15
19
15
19
19
19
13
1.00
1.00
0
0.93
(Histone)(Histone)_(Histone_H2A_C)(TAF)
3
C2
A4B2C2
48
62
195
64
210
65
11
0.88
1.00
0.02
0.98
(Histone)(PHD)
1
C1
AB
24
26
44
35
47
38
0
1.00
0.82
0.25
0.70
(HORMA)(peptide)
1
C1
AB
14
19
18
4
23
5
0
0.82
1.00
0.61
0.72
(Cohesin)(Dockerin_1)
1
C1
AB
11
15
12
18
18
19
8
0.73
1.00
0.67
0.83
(HSP70)(peptide)
1
C1
AB
13
15
41
4
43
6
0
1.00
0.88
0.12
0.17
(IF4E)(peptide)
1
C1
AB
26
27
38
6
39
6
5
0.96
1.00
0.92
0.82
(Inhibitor_I9)(Peptidase_S8)
1
C1
AB
9
9
16
4
16
4
2
1.00
1.00
1.00
0.94
(Kunitz_legume)(Trypsin)
1
C1
AB
12
13
20
9
21
10
8
1.00
0.90
0.80
0.80
(LAG1-DNAbind)_(BTD)_(TIG_SUH)(peptide)
1
C1
AB
5
5
7
2
7
2
16
1.00
1.00
0
0.71
(Cyclin_N)_(Cyclin_C)(Pkinase)
1
C1
AB
30
32
141
15
145
15
4
1.00
0.98
0.89
0.90
(M11L)(peptide)
6
C2
A2B2
8
12
9
4
13
6
0
0.88
0.89
0.89
0.89
(MaoC_dehydrat_N)(MaoC_dehydratas)
1
C1
AB
5
6
8
9
9
10
14
1.00
0.50
0.50
0.50
(MATH)(peptide)
1
C1
AB
21
23
40
6
45
8
0
1.00
0.85
0.53
0.63
(Me-amine-dh_H)(Me-amine-dh_L)
1
C1
AB
7
7
30
6
30
6
8
1.00
0.07
0
0.03
(Me-amine-dh_H)(Me-amine-dh_L)
2
C1
AB
5
7
28
6
30
6
6
0.71
0
0
0.04
(Me-amine-dh_H)(Me-amine-dh_L)
4
C2
A2B2
6
7
29
6
30
6
2
0.85
1.00
0.86
0.90
(MHC_II_alpha)_(C1-set)(MHC_II_beta)_(C1-set)(peptide)
1
C1
ABC
61
75
78
31
95
40
0
1.00
0.95
0.05
0.77
(OTCace_N)_(OTCace)(PyrI)_(PyrI_C)
39
D3
A6B6
7
7
65
8
65
8
5
1.00
1.00
0.91
0.97
(PALP)(Trp_syntA)
1
C1
AB
8
9
136
13
141
15
9
1.00
0.25
0
0.22
(PCNA_N)_(PCNA_C)(peptide)
11
C3
A3B3
29
35
36
8
42
9
0
0.90
0.86
0.47
0.72
(PDGF)(V-set)_(C1-set)
1
C1
AB2
7
11
10
1
14
1
6
0.87
0
0
0.30
(FXa_inhibition)(Trypsin)
1
C1
AB
13
13
147
3
147
3
3
1.00
0.99
0.97
0.91
(Peptidase_M50[117-121])_(PDZ_6)_(PDZ_6)_(Peptidase_M50[122- 150])(V-set)_(C1-set)
1
C1
AB2
6
7
6
2
7
2
3
1.00
0.50
0.17
0.17
(Peptidase_S8)(peptide)
1
C1
AB
13
16
33
10
38
12
13
0.92
1.00
0.91
0.91
(Peptidase_S29)(peptide)
1
C1
AB
7
10
46
12
51
14
9
0.77
0.52
1.00
0.28
(Peptidase_S8)(potato_inhibit)
1
C1
AB
11
11
29
9
29
9
30
1.00
1.00
1.00
0.66
(PK_Tyr_Ser-Thr)(Pkinase)
1
C1
AB
5
7
25
5
27
9
19
1.00
0.96
0.40
0.88
(PKI)(Pkinase)
1
C1
AB
19
19
253
13
255
13
0
1.00
0.96
1.00
0.98
(Pkinase)(peptide)
2
C1
AB
21
117
47
7
457
38
9
0.75
1.00
0.94
0.68
(Plug_translocon)_(SecY)(Sec61_beta)(SecE)
1
C1
ABC
8
15
10
6
17
9
3
1.00
1.00
0.40
1.00
(GP120)(GP41)
3
C3
A3B3
5
6
5
2
6
4
19
1.00
1.00
0
1.00
(PRMT5_TIM)_(PRMT5)_(PRMT5_C)(WD40)_(WD40)_(WD40)_(WD40)_(WD 40)_(WD40)
1
C1
AB
8
9
46
2
49
2
97
1.00
0.74
0.02
0.57
(PRMT5_TIM)_(PRMT5)_(PRMT5_C)(WD40)_(WD40)_(WD40)_(WD40)_(WD 40)_(WD40)
2
C1
AB
7
9
45
2
49
2
97
0.87
0
0
0.09
(PRMT5_TIM)_(PRMT5)_(PRMT5_C)(WD40)_(WD40)_(WD40)_(WD40)_(WD 40)_(WD40)
3
C1
AB
6
9
44
2
49
2
97
0.75
0
0
0.07
(Pro_isomerase)(peptide)
1
C1
AB
24
38
43
19
67
27
30
0.85
0.91
1.00
0.67
(Rad60-SLD)(peptide)
1
C1
AB
10
11
32
4
33
4
0
1.00
0.91
0.81
0.72
(Ras)(zf-RanBP)
3
C2
A2B2
6
6
17
3
17
3
24
1.00
0.06
0
0
(RnaseA)(peptide)
1
C1
AB
6
6
35
1
35
1
0
1.00
1.00
0.37
0.63
(RnaseA)(V-set)
1
C1
AB
8
8
12
2
12
2
90
1.00
1.00
0
0.75
(RuBisCO_large_N)_(RuBisCO_large)(RuBisCO_small)
8
C2
A2B2
17
23
56
38
62
48
0
1.00
0
0.02
0.11
(RuBisCO_large_N)_(RuBisCO_large)(RuBisCO_small)
9
C2
A2B2
17
23
56
38
62
48
3
1.00
0.02
0.27
0.11
(RuBisCO_large_N)_(RuBisCO_large)(RuBisCO_small)
10
C2
A2B2
16
23
55
37
62
48
3
0.93
0.02
0
0.09
(RuBisCO_large_N)_(RuBisCO_large)(RuBisCO_small)
11
C2
A2B2
16
23
55
37
62
48
10
0.93
0
0
0.09
(Serpin)(Trypsin)(peptide)
1
C1
ABC
5
8
5
5
8
8
3
1.00
1.00
0.80
0.80
(SH2)(peptide)
1
C1
AB
63
69
118
36
125
38
0
0.96
0.77
0.42
0.76
(SH3_9)(peptide)
1
C1
AB
18
22
25
12
30
16
0
1.00
0.84
0.20
0.92
(14-3-3)(ADPrib_exo_Tox)
1
C1
AB
5
6
7
6
10
6
10
0.83
0
0
0.14
(14-3-3)(ADPrib_exo_Tox)
2
C2
A2B2
5
6
7
6
10
6
0
0.83
1.00
0.86
0.71
(2Fe-2S_thioredx)(CHCH)(CI-B14_5a)(Complex1_30kDa)(Complex1_ 49kDa)(Complex1_51K)_(SLBB)_(NADH_4Fe-4S)(Complex1_LYR)(dNK) (ESSS)(ETC_C1_NDUFA4)(ETC_C1_NDUFA5)(Fer2_4)_(NADH-G_4Fe-4S_ 3)_(Molybdop_Fe4S4)_(Molybdopterin)_(NADH_dhqG_C)(Fer4_7)(GR IM-19)(L51_S25_CI-B8)(MWFE)(NADH_B2)(NADH_dh_m_C1)(NADH_oxid ored)(NADHdh)(NADHdh_A3)(NDUF_B12)(NDUF_B4)(NDUF_B5)(NDUF_B6 )(NDUF_B7)(NDUF_B8)(NDUF_C2)(NDUFA12)(NDUFB10)(Ndufs5)(NDUFV 3)(NmrA)(Oxidored_q2)(Oxidored_q3)(Oxidored_q4)(Oxidored_q5_ N)_(Proton_antipo_M)(Oxidored_q6)(PP-binding)(Proton_antipo_ M)_(NADH_dehy_S2_C)(Proton_antipo_N)_(Proton_antipo_M)_(NADH 5_C)(Tim17)(zf-CHCC)
1
unknown
ABCDEFG2HIJKLMNOPQRSTUVWXYZabcdefghijklm2nopq
29
29
29
48
29
48
0
1.00
1.00
0.90
1.00
(2Fe-2S_thioredx)(CHCH)(CI-B14_5a)(Complex1_30kDa)(Complex1_ 49kDa)(Complex1_51K)_(SLBB)_(NADH_4Fe-4S)(Complex1_LYR)(dNK) (ESSS)(ETC_C1_NDUFA4)(ETC_C1_NDUFA5)(Fer2_4)_(NADH-G_4Fe-4S_ 3)_(Molybdop_Fe4S4)_(Molybdopterin)_(NADH_dhqG_C)(Fer4_7)(GR IM-19)(L51_S25_CI-B8)(MWFE)(NADH_B2)(NADH_oxidored)(NADHdh)( NADHdh_A3)(NDUF_B12)(NDUF_B4)(NDUF_B5)(NDUF_B6)(NDUF_B7)(NDU F_B8)(NDUF_C2)(NDUFA12)(NDUFB10)(Ndufs5)(NDUFV3)(NmrA)(Oxido red_q2)(Oxidored_q3)(Oxidored_q4)(Oxidored_q5_N)_(Proton_ant ipo_M)(Oxidored_q6)(PP-binding)(Proton_antipo_M)_(NADH_dehy_ S2_C)(Proton_antipo_N)_(Proton_antipo_M)_(NADH5_C)(Tim17)(zf -CHCC)(peptide)
1
unknown
ABCDEFG2HIJKLMNOPQRSTUVWXYZabcdefghijkl2mnopq
8
8
8
37
8
37
100
1.00
1.00
0.63
1.00
(7tm_1)(G-alpha)(G-gamma)(V-set)(WD40)_(WD40)_(WD40)_(WD40)_ (WD40)_(WD40)
1
C1
ABCDE
29
37
29
14
37
17
1
1.00
1.00
0.17
1.00
(7tm_1)(G-alpha)(G-gamma)(V-set)_(V-set)(WD40)_(WD40)_(WD40) _(WD40)_(WD40)_(WD40)
1
C1
ABCDE
43
66
43
30
66
41
3
0.95
1.00
0
1.00
(7tm_1)(G-alpha)(G-gamma)(V-set)_(V-set)(WD40)_(WD40)_(WD40) _(WD40)_(WD40)_(WD40)(peptide)
1
C1
ABCDEF
15
27
15
18
27
26
0
0.88
1.00
0
1.00
(7tm_1)(G-alpha)(G-gamma)(V-set)_(V-set)(ZapB)_(WD40)_(WD40) _(WD40)_(WD40)_(WD40)_(WD40)
1
C1
ABCDE
14
19
14
13
19
19
2
1.00
1.00
0
1.00
(7tm_1)(G-alpha)(G-gamma)(WD40)_(WD40)_(WD40)_(WD40)_(WD40)_ (WD40)
1
C1
ABCD
10
12
10
14
12
17
0
0.90
1.00
1.00
1.00
(7tm_1)(G-alpha)(G-gamma)(WD40)_(WD40)_(WD40)_(WD40)_(WD40)_ (WD40)(peptide)
1
C1
ABCDE
5
8
5
6
8
11
0
1.00
1.00
0.60
1.00
(IBN_N)_(Xpo1)_(CRM1_repeat)_(CRM1_repeat_2)_(CRM1_repeat_3) _(CRM1_C)(Ran_BP1)(Ras)(peptide)
1
C1
ABCD
8
8
31
3
31
3
0
1.00
1.00
1.00
0.45
(IBN_N)_(Xpo1)_(CRM1_repeat)_(CRM1_repeat_2)_(CRM1_repeat_3) _(CRM1_C)(Ran_BP1)(Ras)(peptide)
2
C1
ABCD
8
8
31
3
31
3
0
1.00
0
0
0
(IBN_N)_(Xpo1)_(CRM1_repeat)_(CRM1_repeat_2)_(CRM1_repeat_3) _(CRM1_C)(Ran_BP1)(Ras)(peptide)
3
C1
ABCD
8
8
31
3
31
3
0
1.00
0
0
0
(IBN_N)_(Xpo1)_(CRM1_repeat)_(CRM1_repeat_2)_(CRM1_repeat_3) _(CRM1_C)(Ran_BP1)(Ras)(peptide)
4
C1
ABCD
8
8
31
3
31
3
0
1.00
0
0
0
(IBN_N)_(Xpo1)_(CRM1_repeat)_(CRM1_repeat_2)_(CRM1_repeat_3) _(CRM1_C)(Ran_BP1)(Ras)(peptide)
5
C1
ABCD
8
8
31
3
31
3
0
1.00
0
0
0
(IBN_N)_(Xpo1)_(CRM1_repeat)_(CRM1_repeat_2)_(CRM1_repeat_3) _(CRM1_C)(Ran_BP1)(Ras)(peptide)
6
C1
ABCD
8
8
31
3
31
3
0
1.00
0
0
0
(IBN_N)_(Xpo1)_(CRM1_repeat)_(CRM1_repeat_2)_(CRM1_repeat_3) _(CRM1_C)(Ran_BP1)(Ras)(peptide)
7
C1
ABCD
8
8
31
3
31
3
0
1.00
0
0
0
(IBN_N)_(Xpo1)_(CRM1_repeat)_(CRM1_repeat_2)_(CRM1_repeat_3) _(CRM1_C)(Ran_BP1)(Ras)(peptide)
8
C1
ABCD
8
8
30
3
31
3
0
1.00
0
0
0
(IBN_N)_(Xpo1)_(CRM1_repeat)_(CRM1_repeat_2)_(CRM1_repeat_3) _(CRM1_C)(Ran_BP1)(Ras)(peptide)
9
C1
ABCD
8
8
30
3
31
3
0
1.00
0
0
0
(IBN_N)_(Xpo1)_(CRM1_repeat)_(CRM1_repeat_2)_(CRM1_repeat_3) _(CRM1_C)(Ran_BP1)(Ras)(peptide)
10
C1
ABCD
7
8
29
3
31
3
0
0.87
0
0
0
(IBN_N)_(Xpo1)_(CRM1_repeat)_(CRM1_repeat_2)_(CRM1_repeat_3) _(CRM1_C)(Ran_BP1)(Ras)(peptide)
11
C1
ABCD
7
8
29
3
31
3
0
0.87
0
0
0
(IBN_N)_(Xpo1)_(CRM1_repeat)_(CRM1_repeat_2)_(CRM1_repeat_3) _(CRM1_C)(Ran_BP1)(Ras)(peptide)
12
C1
ABCD
7
8
29
3
31
3
0
0.87
0
0
0
(IBN_N)_(Xpo1)_(CRM1_repeat)_(CRM1_repeat_2)_(CRM1_repeat_3) _(CRM1_C)(Ran_BP1)(Ras)(peptide)
13
C1
ABCD
6
8
25
3
31
3
0
0.75
0
0
0
(IBN_N)_(Xpo1)_(CRM1_repeat)_(CRM1_repeat_2)_(CRM1_repeat_3) _(CRM1_C)(Ran_BP1)(Ras)(peptide)
14
C1
ABCD
6
8
25
3
31
3
0
0.75
0
0
0
(IBN_N)_(Xpo1)_(CRM1_repeat)_(CRM1_repeat_2)_(CRM1_repeat_3) _(CRM1_C)(Ran_BP1)(Ras)(peptide)
15
C1
ABCD
6
8
25
3
31
3
0
0.75
0
0
0
(IBN_N)_(Xpo1)_(CRM1_repeat)_(CRM1_repeat_2)_(CRM1_repeat_3) _(CRM1_C)(Ran_BP1)(Ras)(peptide)
16
C1
ABCD
6
8
25
3
31
3
0
0.75
0
0
0
(IBN_N)_(Xpo1)_(CRM1_repeat)_(CRM1_repeat_2)_(CRM1_repeat_3) _(CRM1_C)(Ran_BP1)(Ras)(peptide)
17
C1
ABCD
6
8
24
3
31
3
0
0.75
0
0
0
(TSP_1)(V-set)_(C1-set)
1
C1
AB2
5
9
5
2
9
4
28
1.00
1.00
0
0.80
(AA_permease_2)(SLC3A2_N)_(Alpha-amylase)_(DUF3459)
1
C1
AB
15
15
15
9
15
9
25
1.00
0.80
0.67
1.00
(AAA)_(AAA_lid_3)(peptide)
1
C1
A6B
7
10
7
4
10
4
28
1.00
1.00
0
1.00
(AAA)_(Cdc6_C)(AAA_16)_(ORC4_C)(AAA_16)_(ORC5_C)(AAA_22)_(Cd c6_C)(ORC2)(ORC3_N)_(ORC3_ins)_(ORC_WH_C)(ORC6)
1
C1
ABCDEFG
5
5
5
7
5
7
100
1.00
1.00
1.00
1.00
(AAA_30)_(UvrD_C_2)(Exonuc_V_gamma)_(RecC_C)(UvrD-helicase)_ (UvrD_C)
1
C1
ABC
8
8
14
5
14
5
98
1.00
1.00
0.71
1.00
(AAA_5)(McrBC)
1
C2
A12B2
6
9
6
4
9
4
4
0.75
1.00
0
1.00
(ABC_membrane)_(ABC_tran)_(CFTR_R)_(ABC_membrane)_(ABC_tran) (peptide)
1
C1
AB
7
9
7
1
9
1
100
0.77
1.00
0
1.00
(ABC_membrane)_(ABC_tran)(V-set)
1
C1
A2B
9
18
9
2
19
9
100
1.00
1.00
1.00
1.00
(ABC_tran)_(Wzt_C)(ABC2_membrane)
1
C1
AB
7
7
7
2
7
2
100
1.00
0
0
1.00
(ABC_tran)_(Wzt_C)(ABC2_membrane)
3
C2
A2B2
7
7
7
2
7
2
100
1.00
1.00
0.43
1.00
(V-set)_(C1-set)(V-set_2)
1
C1
A2B
5
7
5
1
7
2
15
1.00
1.00
0.40
1.00
(Acetyltransf_1)(peptide)
1
C1
AB
16
17
20
11
21
11
9
1.00
0.75
0.30
0.50
(V-set)_(V-set)(peptide)
1
C1
AB
10
16
21
4
27
4
0
1.00
0.90
0.10
0.86
(ACP_syn_III)(ACP_syn_III)_(ACP_syn_III_C)
1
C1
AB
5
5
6
4
6
4
99
1.00
0.83
1.00
0.50
(Actin)(peptide)
1
C1
AB
18
21
21
4
24
5
5
1.00
0.76
0.38
0.76
(Actin)(RPEL)
1
C1
AB
6
6
7
4
7
4
26
1.00
0.86
1.00
1.00
(Y_phosphatase)(peptide)
1
C1
AB
18
25
28
6
40
9
31
1.00
0.96
0.89
0.93
(Adap_comp_sub)(peptide)
1
C1
AB
5
8
13
4
17
6
11
1.00
1.00
0
0.85
(Thrombin_light)(Trypsin)(peptide)
1
C1
ABC
19
20
37
3
41
3
0
0.95
0.97
0.11
0.65
(ADD_ATRX)_(PHD)(Histone)
1
C1
AB
5
5
5
3
5
3
95
1.00
0.80
0.80
0.80
(ADD_ATRX)_(PHD)(peptide)
1
C1
AB
5
5
5
1
5
1
95
1.00
0.80
0.80
0.80
(14-3-3)(peptide)
3
C2
A2B2
80
101
379
14
431
18
8
0.88
0.98
0.29
0.81
(2OG-FeII_Oxy_3)(peptide)
1
C1
AB
5
10
7
2
15
3
17
0.83
0.86
0.86
0.57
(Aldo_ket_red)(BTB_2)_(Ion_trans)
1
C1
AB
7
8
10
6
13
6
66
0.87
0
0
0.40
(Aldo_ket_red)(BTB_2)_(Ion_trans)
2
C1
AB
7
8
10
6
13
6
66
0.87
0
0
0.40
(Aldo_ket_red)(BTB_2)_(Ion_trans)
3
C4
A4B4
8
8
13
6
13
6
66
1.00
0.92
0
0.77
(Alpha_E1_glycop)(Alpha_E2_glycop)_(Alpha_E1_glycop)(Peptida se_S3)
1
C1
ABC
8
9
8
10
9
11
2
1.00
0
0.13
1.00
(AMA-1)(peptide)
1
C1
AB
8
8
14
8
14
8
0
1.00
1.00
0.57
0.79
(AMO)(AmoC)(Monooxygenase_B)
7
C3
A3B3C3
11
11
12
7
12
7
3
1.00
1.00
0.67
0.83
(ANF_receptor)_(7tm_3)(ANF_receptor)_(7tm_3)_(GBR2_CC)
1
C1
AB
6
6
6
2
6
2
98
1.00
1.00
0.17
1.00
(Ion_trans_2)(V-set)_(C1-set)
1
C1
AB2
6
8
79
4
84
5
0
0.75
0.15
0
0.15
(Ion_trans_2)(V-set)_(C1-set)
2
C1
AB2
6
8
79
4
84
5
0
0.75
0
0
0.11
(Ion_trans_2)(V-set)_(C1-set)
3
C1
AB2
6
8
79
4
84
5
67
0.75
0
0
0.11
(Ion_trans_2)(V-set)_(C1-set)
4
C1
AB2
6
8
79
4
84
5
67
0.75
0
0
0.11
(Ank_2)_(Ank_2)(peptide)
2
C1
AB
5
15
5
2
20
7
0
0.71
0.80
0.80
0.80
(APC_rep)_(Arm)_(Arm)_(Arm)_(Arm)_(Arm_APC_u3)(peptide)
1
C1
AB
5
6
9
1
10
1
9
0.83
1.00
0.67
0.67
(APG5)(ATG16)
1
C1
AB
5
5
5
2
5
2
87
1.00
0.80
1.00
0.20
(APP_amyloid)(PID)
1
C1
AB
6
6
9
9
9
9
12
1.00
0.78
1.00
0.33
(Arf)(GMP_PDE_delta)
1
C1
AB
5
5
6
5
6
5
21
1.00
1.00
1.00
0.83
(Adaptin_N)(Clat_adaptor_s)(Clat_adaptor_s)_(Adap_comp_sub)
1
C1
A2BC
8
12
10
12
14
16
0
1.00
0.90
0.90
0.90
(Asp)(peptide)
1
C1
AB
38
45
71
24
80
29
3
0.97
0.97
0.72
0.69
(ArsA_ATPase)(CHD5)
1
C1
AB
5
5
6
2
6
2
12
1.00
0
0.17
0
(ArsA_ATPase)(CHD5)
4
C2
A2B2
5
5
6
2
6
2
7
1.00
1.00
0
0.50
(Arylesterase)_(VWA)_(FG-GAP)_(FG-GAP)_(Integrin_alpha2)(PSI _integrin)_(Integrin_beta)_(EGF_2)_(Integrin_B_tail)
1
C1
AB
5
5
6
2
6
2
98
1.00
1.00
0.83
0.33
(Asp_decarbox)(peptide)
18
C4
A4B4
7
7
17
6
17
6
0
1.00
0.94
0
0.88
(ATP_synt_H)(ATP-synt_ab_N)_(ATP-synt_ab)(ATP-synt_ab_N)_(AT P-synt_ab_Xtn)_(ATP-synt_ab)(ATP-synt_C)_(ATP-synt_C)(ATP-sy nt_D)(ATP-synt_F)(ATP-synt_S1)(Tetraspanin)(V_ATPase_I)(V-AT Pase_C)(V-ATPase_G)(V-ATPase_H_N)_(V-ATPase_H_C)(vATP-synt_A C39)(vATP-synt_E)
1
unknown
AB3C3D10EFGHIJK3LMN3
7
7
7
25
7
25
10
1.00
1.00
0.43
1.00
(ATP_synth_reg)(ATP-synt)(ATP-synt_8)(ATP-synt_A)(ATP-synt_a b_N)_(ATP-synt_ab)_(ATP-synt_ab_C)(ATP-synt_ab_N)_(ATP-synt_ ab)_(T3SS_ATPase_C)(ATP-synt_C)(ATP-synt_DE_N)(ATP-synt_E)(A TP-synt_Eps)(ATP-synt_F6)(ATP-synt_G)(IATP)(Mit_proteolip)(M t_ATP-synt_B)(Mt_ATP-synt_D)(OSCP)(WRW)
1
unknown
ABCDE3F3G8HIJKLMNOPQR
10
12
10
19
12
19
13
0.83
0.30
0.30
1.00
(ATP_synth_reg)(ATP-synt)(ATP-synt_8)(ATP-synt_A)(ATP-synt_a b_N)_(ATP-synt_ab)_(ATP-synt_ab_C)(ATP-synt_ab_N)_(ATP-synt_ ab)_(T3SS_ATPase_C)(ATP-synt_C)(ATP-synt_DE_N)(ATP-synt_E)(A TP-synt_F6)(ATP-synt_G)(IATP)(Mit_proteolip)(Mt_ATP-synt_B)( Mt_ATP-synt_D)(OSCP)(WRW)(peptide)
1
unknown
ABCDE3F3G8HIJKLMNOPQR
10
12
10
18
12
18
13
0.83
0.30
0.30
1.00
(ATP-synt)(ATP-synt_A)(ATP-synt_ab_N)_(ATP-synt_ab)_(ATP-syn t_ab_C)(ATP-synt_ab_N)_(ATP-synt_ab)_(T3SS_ATPase_C)(ATP-syn t_C)(ATP-synt_DE_N)_(ATP-synt_DE)(ATP-synt_Eps)(ATP-synt_F6) (Mt_ATP-synt_B)(Mt_ATP-synt_D)(OSCP)
1
unknown
ABC3D3E8FGHIJK
6
7
6
11
7
11
0
1.00
1.00
0
1.00
(ATP-synt)(ATP-synt_A)(ATP-synt_ab_N)_(ATP-synt_ab)_(ATP-syn t_ab_C)(ATP-synt_ab_N)_(ATP-synt_ab)_(T3SS_ATPase_C)(ATP-syn t_C)(ATP-synt_DE_N)_(ATP-synt_DE)(ATP-synt_F6)(Mt_ATP-synt_B )(Mt_ATP-synt_D)(OSCP)(peptide)
1
unknown
ABC3D3E8FGHIJK
6
7
6
10
7
10
100
1.00
1.00
0
1.00
(ATP-synt_ab_N)_(ATP-synt_ab)_(T3SS_ATPase_C)(ATP-synt_ab_N) _(ATP-synt_ab_Xtn)_(ATP-synt_ab)
3
C3
A3B3
5
5
8
6
8
6
11
1.00
1.00
0.25
0.88
(Aurora-A_bind)(Pkinase)
1
C1
AB
5
5
5
2
5
2
97
1.00
0.80
0.80
0.40
(Avidin)(peptide)
22
D2
A4B4
7
10
42
1
50
2
0
1.00
0.98
0
0.57
(B)(C1-set)_(C1-set)
1
C1
AB
6
9
10
7
13
8
24
0.75
0.20
0
0.20
(B)(C1-set)_(C1-set)
7
C2
A2B2
7
9
11
7
13
8
24
0.87
0.82
0.45
0.36
(Bcl-2)(peptide)
1
C1
AB
62
69
82
19
90
20
0
0.96
0.78
0.85
0.62
(Barstar)(Ribonuclease)
1
C1
AB
6
6
15
3
15
3
18
1.00
1.00
1.00
0.07
(Bcl-2)(BH4)_(Bcl-2)
1
C1
AB
8
8
9
8
9
8
0
1.00
0.67
0.44
0.56
(Bcl-2)(M11L)
1
C1
AB
5
6
6
7
7
8
10
0.83
0.33
0.17
0.33
(Bcl-2)(PMAIP1)
1
C1
AB
5
5
6
5
6
5
9
1.00
0.67
1.00
0.83
(Bclx_interact)(BH4)_(Bcl-2)
1
C1
AB
13
13
14
6
14
6
6
1.00
0.64
0.36
0.43
(ANF_receptor)_(Lig_chan-Glu_bd)_(Lig_chan)_(CaM_bdg_C0)(ANF _receptor)_(Lig_chan-Glu_bd)_(Lig_chan)_(NMDAR2_C)
2
C2
A2B2
21
26
21
4
26
5
26
1.00
1.00
0.57
1.00
(ANF_receptor)_(Lig_chan-Glu_bd)_(Lig_chan)(ANF_receptor)_(L ig_chan-Glu_bd)_(Lig_chan)_(CaM_bdg_C0)
3
C2
A2B2
10
16
10
3
16
4
26
1.00
1.00
0.20
1.00
(Ank_2)_(Ank_4)(peptide)
1
C1
AB
5
6
6
1
7
1
0
1.00
1.00
0.83
1.00
(BH3)(BH4)_(Bcl-2)
1
C1
AB
5
5
7
4
7
4
9
1.00
0.71
0.57
0.57
(BIR)(peptide)
1
C1
AB
17
20
38
8
41
8
20
0.89
0.58
0.08
0.42
(BIR)(Smac_DIABLO)
1
C1
AB
6
7
8
6
9
6
29
1.00
0.38
0
0.25
(BRCT)_(BRCT)(peptide)
1
C1
AB
8
8
16
1
17
1
0
1.00
1.00
1.00
0.69
(Bromodomain)(Histone)
1
C1
AB
7
9
9
10
15
14
11
1.00
1.00
0.33
0.67
(BTB)_(BACK)(Cullin)
1
C1
AB
5
5
6
6
6
6
20
1.00
0.50
0.17
0.17
(BTB)_(BACK)(Cullin)
3
C2
A2B2
5
5
6
6
6
6
6
1.00
0.67
0.83
0.83
(ATP1G1_PLM_MAT8)(Cation_ATPase_N)_(E1-E2_ATPase)_(Cation_AT Pase)_(Cation_ATPase_C)(Na_K-ATPase)
1
C1
ABC
25
25
62
11
62
11
4
1.00
0.95
0
0.94
(ATP1G1_PLM_MAT8)(Cation_ATPase_N)_(E1-E2_ATPase)_(Cation_AT Pase)_(Cation_ATPase_C)(Na_K-ATPase)
2
C1
ABC
14
25
47
6
62
11
29
0.82
0
0
0.23
(ATP1G1_PLM_MAT8)(Cation_ATPase_N)_(E1-E2_ATPase)_(Cation_AT Pase)_(Cation_ATPase_C)(Na_K-ATPase)
3
C1
ABC
14
25
47
6
62
11
29
0.82
0
0
0.23
(ATP-grasp_2)_(Ligase_CoA)(CoA_binding)_(Ligase_CoA)
1
C1
AB
11
11
33
13
33
13
7
1.00
0.67
0.97
0.58
(C1-set)(EBV-NA3)(MHC_I)_(C1-set)(V-set)_(C1-set)(V-set)_(DU F1968)
1
C1
ABCDE
5
5
5
7
5
7
0
1.00
1.00
0.40
0
(Avidin)(peptide)
6
C2
A2B2
7
10
41
1
50
2
0
1.00
0.02
0
0
(Avidin)(peptide)
7
C2
A2B2
7
10
41
1
50
2
0
1.00
0
0.20
0.10
(Avidin)(peptide)
8
C2
A2B2
7
10
41
1
50
2
12
1.00
0
0
0
(Avidin)(peptide)
9
C2
A2B2
7
10
38
1
50
2
17
1.00
0
0
0
(Avidin)(peptide)
10
C2
A2B2
7
10
38
1
50
2
12
1.00
0
0
0
(Bcl-2)(Bclx_interact)
1
C1
AB
20
21
31
12
32
12
6
0.95
0.71
0.77
0.45
(Bcl-2)(PUMA)
1
C1
AB
8
9
9
8
10
9
0
1.00
0.67
1.00
0.56
(MHC_II_alpha)_(C1-set)(MHC_II_beta)_(C1-set)(V-set)_(C1-set )(V-set)_(DUF1968)(peptide)
1
C1
ABCDE
30
36
41
33
48
37
0
0.93
0.98
0.63
0.34
(C1-set)(MHC_I)_(C1-set)(Pico_P1A)(Rhv)
1
C1
ABCD3
5
5
5
10
5
10
2
1.00
1.00
0.20
1.00
(C1-set)(MHC_I)_(C1-set)(Telomerase_RBD)
1
C1
ABC
5
5
5
3
5
3
0
1.00
1.00
0
0.40
(MHC_II_alpha)_(C1-set)(MHC_II_beta)_(C1-set)(V-set)_(C1-set )(V-set)_(DUF1968)
1
C1
ABCD
13
13
18
19
18
19
2
1.00
0.83
0.11
0.33
(C1-set)_(C1-set)(Ig_2)_(Ig_2)
1
C1
A2B
10
10
14
7
14
7
47
1.00
1.00
0
0.07
(Beta-APP)(V-set)_(C1-set)
1
C1
AB2
16
16
18
7
18
7
0
1.00
1.00
0.06
0.89
(Beta-lactamase2)(BLIP)
1
C1
AB
7
8
14
6
15
7
37
1.00
1.00
1.00
1.00
(BTB)(peptide)
6
C2
A2B2
6
7
24
2
36
2
6
1.00
0.92
0
0.83
(C1-set)(Flu_M1)(MHC_I)_(C1-set)(V-set)_(C1-set)(V-set)_(DUF 1968)
1
C1
ABCDE
8
8
9
5
9
5
0
1.00
1.00
0
0.22
(C1-set)(Flu_NP)(MHC_I)_(C1-set)
1
C1
ABC
21
21
29
27
29
27
0
1.00
0.90
0.03
0.76
(C1-set)(F-protein)(MHC_I)_(C1-set)
1
C1
ABC
9
10
26
19
27
21
0
1.00
1.00
0
0.96
(C1-set)(F-protein)(MHC_I)_(C1-set)(V-set)_(C1-set)(V-set)_( DUF1968)
1
C1
ABCDE
6
7
8
6
9
7
0
0.85
1.00
0.38
1.00
(C1-set)(ig)_(ig)_(ig)(MHC_I)_(C1-set)(peptide)
1
C1
ABCD
6
6
8
5
8
5
0
1.00
1.00
0
0.63
(C1-set)(ig)_(ig)_(ig)(MHC_I)_(C1-set)(peptide)
2
C1
ABCD
6
6
8
5
8
5
0
1.00
0
0
0.13
(C1-set)(ig)_(ig)_(ig)(MHC_I)_(C1-set)(peptide)
3
C1
ABCD
6
6
8
5
8
5
13
1.00
0
0
0
(C1-set)(ig)_(ig)_(ig)(MHC_I)_(C1-set)(peptide)
4
C1
ABCD
6
6
8
5
8
5
13
1.00
0
0
0
(C1-set)(ig)_(ig)_(ig)(MHC_I)_(C1-set)(peptide)
5
C1
ABCD
6
6
8
5
8
5
0
1.00
0
0
0
(C1-set)(ig)_(ig)_(ig)(MHC_I)_(C1-set)(peptide)
6
C1
ABCD
6
6
8
5
8
5
0
1.00
0
0
0
(C1-set)(ig)_(ig)_(ig)(MHC_I)_(C1-set)(peptide)
7
C1
ABCD
6
6
8
5
8
5
0
1.00
0
0
0
(C1-set)(ig)_(ig)_(ig)(MHC_I)_(C1-set)(peptide)
8
C1
ABCD
6
6
8
5
8
5
88
1.00
0
0
0
(C1-set)(ig)_(ig)_(ig)(MHC_I)_(C1-set)(peptide)
9
C1
ABCD
6
6
8
5
8
5
88
1.00
0
0
0
(C1-set)(ig)_(ig)_(ig)(MHC_I)_(C1-set)(peptide)
10
C1
ABCD
6
6
8
5
8
5
88
1.00
0
0
0
(C1-set)(ig)_(ig)_(ig)(MHC_I)_(C1-set)(peptide)
11
C1
ABCD
6
6
8
5
8
5
88
1.00
0
0
0
(C1-set)(ig)_(ig)_(ig)(MHC_I)_(C1-set)(peptide)
12
C1
ABCD
6
6
8
5
8
5
5
1.00
0
0
0
(C1-set)(ig)_(ig)_(ig)(MHC_I)_(C1-set)(peptide)
13
C1
ABCD
6
6
8
5
8
5
88
1.00
0
0
0
(C1-set)(ig)_(ig)_(ig)(MHC_I)_(C1-set)(peptide)
14
C1
ABCD
6
6
8
5
8
5
88
1.00
0
0
0
(C1-set)(ig)_(ig)_(ig)(MHC_I)_(C1-set)(peptide)
15
C1
ABCD
6
6
8
5
8
5
88
1.00
0
0
0
(C1-set)(ig)_(ig)_(ig)(MHC_I)_(C1-set)(peptide)
16
C1
ABCD
6
6
8
5
8
5
88
1.00
0
0
0
(C1-set)(ig)_(ig)_(ig)(MHC_I)_(C1-set)(peptide)
17
C1
ABCD
5
6
7
4
8
5
0
0.83
0
0
0
(C1-set)(ig)_(ig)_(ig)(MHC_I)_(C1-set)(peptide)
18
C1
ABCD
5
6
7
4
8
5
13
0.83
0
0
0
(C1-set)(ig)_(ig)_(ig)(MHC_I)_(C1-set)(peptide)
19
C1
ABCD
5
6
7
4
8
5
5
0.83
0
0
0
(C1-set)(ig)_(ig)_(ig)(MHC_I)_(C1-set)(peptide)
20
C1
ABCD
5
6
7
4
8
5
90
0.83
0
0
0
(C1-set)(ig)_(ig)_(ig)(MHC_I)_(C1-set)(peptide)
21
C1
ABCD
5
6
7
4
8
5
90
0.83
0
0
0
(C1-set)(ig)_(ig)_(ig)(MHC_I)_(C1-set)(peptide)
22
C1
ABCD
5
6
7
4
8
5
90
0.83
0
0
0
(C1-set)(ig)_(ig)_(ig)(MHC_I)_(C1-set)(peptide)
23
C1
ABCD
5
6
7
4
8
5
90
0.83
0
0
0
(C1-set)(ig)_(ig)_(ig)(MHC_I)_(C1-set)(peptide)
24
C1
ABCD
5
6
7
4
8
5
90
0.83
0
0
0
(C1-set)(ig)_(ig)_(ig)(MHC_I)_(C1-set)(peptide)
25
C1
ABCD
5
6
7
4
8
5
90
0.83
0
0
0
(C1-set)(ig)_(ig)_(ig)(MHC_I)_(C1-set)(peptide)
26
C1
ABCD
5
6
7
4
8
5
90
0.83
0
0
0
(C1-set)(ig)_(ig)_(ig)(MHC_I)_(C1-set)(peptide)
27
C1
ABCD
5
6
7
4
8
5
90
0.83
0
0
0
(Ca_chan_IQ)(EF-hand_7)_(EF-hand_7)
1
C1
AB
9
12
15
8
21
11
0
0.75
0.93
0.80
0.73
(CAF1C_H4-bd)_(WD40)_(WD40)_(WD40)(peptide)
1
C1
AB
6
7
6
2
12
2
0
0.85
1.00
0.83
0.67
(Calici_coat)(CRPV_capsid)(Rhv)
1
C1
ABC
11
13
11
9
13
9
11
1.00
0.91
0.82
0.82
(CAMSAP_CKK)(Tubulin)_(Tubulin_C)
1
C1
AB4
7
7
7
7
7
7
5
1.00
1.00
0
1.00
(CarD_CdnL_TRCF)(RbpA)(RNA_pol_L[1-30])_(RNA_pol_A_bac)_(RNA _pol_L[31-73])_(RNA_pol_A_CTD)(RNA_pol_Rpb1_1)_(RNA_pol_Rpb1 _2)_(RNA_pol_Rpb1_3)_(RNA_pol_Rpb1_5)(RNA_pol_Rpb2_2)_(RNA_p ol_Rpb2_3)_(RNA_pol_Rpb2_45)_(RNA_pol_Rpb2_6)_(RNA_pol_Rpb2_ 7)(RNA_pol_Rpb6)(Sigma70_r1_2)_(Sigma70_r2)_(Sigma70_r3)_(Si gma70_r4)
1
unknown
ABC2DEFG
5
5
5
7
5
7
3
1.00
1.00
1.00
1.00
(Cbl_N)_(Cbl_N2)_(Cbl_N3)(peptide)
7
C2
A2B2
5
11
11
2
22
4
0
0.83
0
0.18
0.09
(Cas_Cas1)(CRISPR_Cas2)
1
C2
A4B2
5
6
5
4
6
6
18
1.00
1.00
0
0.60
(Cation_ATPase_N)_(E1-E2_ATPase)_(Cation_ATPase)_(Cation_ATP ase_C)(Na_K-ATPase)
1
C1
AB
8
8
13
5
13
5
31
1.00
1.00
1.00
1.00
(C1-set)(MHC_I)_(C1-set)(peptide)
1
C1
ABC
367
380
862
119
885
125
0
0.98
0.99
0.04
0.91
(CDC45)(MCM_N)_(MCM_OB)_(MCM)_(MCM_lid)(MCM_N)_(MCM_OB)_(MCM )_(MCM_lid)_(MCM6_C)(MCM2_N)_(MCM_N)_(MCM_OB)_(MCM)_(MCM_lid )(Sld5)(Sld5)_(SLD5_C)
1
C1
AB4CDE2F2
5
5
5
11
5
11
2
1.00
1.00
1.00
1.00
(CDC50)(PhoLip_ATPase_N)_(Cation_ATPase)_(PhoLip_ATPase_C)
1
C1
AB
9
9
9
5
9
5
28
1.00
1.00
1.00
1.00
(CDC50)(PhoLip_ATPase_N)_(E1-E2_ATPase)_(Cation_ATPase)_(Pho Lip_ATPase_C)
1
C1
AB
17
17
17
3
17
3
36
1.00
1.00
1.00
0.94
(CDC50)(PhoLip_ATPase_N)_(PhoLip_ATPase_C)
1
C1
AB
14
14
14
7
14
7
34
1.00
1.00
1.00
1.00
(CENP-S)(CENP-X)
1
C1
AB
8
9
9
6
10
6
8
0.88
0.11
0.78
0.33
(CHCH)(CR6_interact)(DAP3)(DUF1713)(Img2)(KOW)_(ribosomal_L2 4)(L51_S25_CI-B8)(Mitoc_L55)(MRP_L53)(MRP-63)(MRP-L27)(MRP-L 28)(MRP-L46)(MRP-L47)(MRP-L51)(MRPL52)(MRP-S22)(MRP-S23)(MRP -S24)(MRP-S26)(MRP-S27)(MRP-S28)(MRP-S31)(MRP-S32)(MRP-S33)( MRP-S34)(MRP-S35)(PBP)(PDCD9)(PPR_2)_(PPR_2)_(PPR_2)_(PPR)_( PPR)(RF-1)(Ribonucleas_3_3)_(dsrm)(Ribosom_S12_S23)(Ribosoma l_L10)(Ribosomal_L11_N)_(Ribosomal_L11)(Ribosomal_L12_N)_(Ri bosomal_L12)(Ribosomal_L13)(Ribosomal_L14)(Ribosomal_L16)(Ri bosomal_L17)(Ribosomal_L18p)(Ribosomal_L19)(Ribosomal_L2)_(R ibosomal_L2_C)(Ribosomal_L20)(Ribosomal_L21p)(Ribosomal_L22) (Ribosomal_L23)(Ribosomal_L27)(Ribosomal_L27A)(Ribosomal_L28 )(Ribosomal_L3)(Ribosomal_L30)(Ribosomal_L32p)(Ribosomal_L33 )(Ribosomal_L34)(Ribosomal_L35p)(Ribosomal_L36)(Ribosomal_L3 7)(Ribosomal_L4)(Ribosomal_L50)(Ribosomal_L9_N)_(Ribosomal_L 9_C)(Ribosomal_S10)(Ribosomal_S11)(Ribosomal_S14)(Ribosomal_ S15)(Ribosomal_S16)(Ribosomal_S17)(Ribosomal_S18)(Ribosomal_ S2)(Ribosomal_S21)(Ribosomal_S5)_(Ribosomal_S5_C)(Ribosomal_ S6)(Ribosomal_S7)(Ribosomal_S9)(TGS)_(tRNA_SAD)(Tim44)
1
unknown
ABCDEFG2HIJKLMNOPQRSTUVWXYZabc2defghij6klmnopqrstuvwxyz01234567892(AA)(AB)(AC)(AD)(AE)(AF)3(AG)(AH)(AI)(AJ)(AK)(AL)(AM)(AN)
7
7
7
85
7
85
9
1.00
1.00
0.57
1.00
(CID)(peptide)
1
C1
AB
8
9
15
6
16
6
0
1.00
0.67
0.67
0.67
(Clp_N)_(Clp_N)_(AAA)_(AAA_lid_9)_(AAA_2)_(ClpB_D2-small)(Me cA)
1
C1
AB
5
5
5
2
5
2
99
1.00
0
0
1.00
(Clp_N)_(Clp_N)_(AAA)_(AAA_lid_9)_(AAA_2)_(ClpB_D2-small)(Me cA)
2
C1
AB
5
5
5
2
5
2
99
1.00
0
0
0.80
(Clp_N)_(Clp_N)_(AAA)_(AAA_lid_9)_(AAA_2)_(ClpB_D2-small)(Me cA)
3
C6
A6B6
5
5
5
2
5
2
81
1.00
0.80
1.00
0.80
(Clp_N)_(Clp_N)_(AAA)_(AAA_lid_9)_(AAA_2)_(ClpB_D2-small)(pe ptide)
1
C1
A6B
16
19
16
5
19
6
42
1.00
1.00
0
1.00
(CLP_protease)(peptide)
1
C1
AB
6
13
12
5
24
13
51
1.00
0
0
0.17
(CLP_protease)(peptide)
2
C1
AB
6
13
11
5
24
13
51
1.00
0
0
0.18
(CLP_protease)(peptide)
22
C7
A7B7
6
13
12
5
24
13
51
1.00
0.25
0
0.17
(ClpS)(peptide)
1
C1
AB
6
6
10
2
11
2
14
1.00
1.00
0.70
0.50
(C1-set)(MHC_I)_(C1-set)(Pcc1)(V-set)_(C1-set)(V-set)_(DUF19 68)
1
C1
ABCDE
6
6
11
7
11
7
0
1.00
0.91
0.73
0.64
(Complex1_30kDa)(Complex1_49kDa)(Fer4_7)(NADHdh)(NdhL)(NdhM) (NdhN)(NdhO)(NdhS)(Oxidored_q2)(Oxidored_q3)(Oxidored_q4)(Ox idored_q5_N)_(Proton_antipo_M)(Oxidored_q6)(Proton_antipo_N) _(Proton_antipo_M)(Proton_antipo_N)_(Proton_antipo_M)_(Proto n_antipo_C)(peptide)
1
C1
ABCDEFGHIJKLMNOPQ2
5
6
5
16
6
16
0
1.00
1.00
1.00
1.00
(CoV_Methyltr_2)(CoV_NSP10)
1
C1
AB
8
9
44
7
56
7
5
1.00
1.00
0.80
0.41
(CoV_ExoN)(CoV_NSP10)
1
C1
AB
7
7
9
3
9
3
18
1.00
1.00
0.89
1.00
(CoV_NSP7)(CoV_NSP8)
1
C1
AB
6
7
10
4
11
5
4
1.00
0
0
0
(CoV_NSP7)(CoV_NSP8)
2
C1
AB
6
7
10
4
11
5
4
1.00
0.40
1.00
0.10
(CoV_S2)(peptide)
1
C1
AB
5
7
5
3
7
3
3
0.83
0
0
0
(COX1)(COX2-transmemb)_(COX2)(CoxIIa)
1
C1
ABC
6
6
36
3
37
3
5
1.00
1.00
0.94
1.00
(CoV_S2)(peptide)
6
C3
A3B3
5
6
5
3
6
3
3
0.83
1.00
0
0.80
(COX1)(COX2_TM)_(COX2)(COX3)(COX4_pro_2)
1
C1
ABCD
5
5
7
8
7
8
4
1.00
1.00
0
1.00
(COX1)(COX2_TM)_(COX2)(COX3)(peptide)
1
C1
ABCD
5
5
5
6
5
6
4
1.00
1.00
0
1.00
(CP12)(Gp_dh_N)_(Gp_dh_C)
8
C2
A2B4
5
7
6
4
10
6
0
0.83
1.00
0
0.67
(Cpn10)(Cpn60_TCP1)
5
C7
A7B14
8
14
12
4
20
8
11
0.88
1.00
0
0.42
(CybS)(FAD_binding_2)_(Succ_DH_flav_C)(Fer2_3)_(Fer4_17)(Sdh _cyt)
1
C1
ABCD
8
9
60
24
61
28
2
1.00
0.95
0.47
0.65
(Cytochrom_B559)(Cytochrom_B559)_(Cytochrom_B559a)(Cytochrom _C550)(MSP)(Photo_RC)(PsbH)(PsbI)(PsbJ)(PsbK)(PsbL)(PsbM)(Ps bT)(PsbU)(PsbX)(PsbY)(PSII)(PSII_Ycf12)(Ycf9)
1
C1
ABCDE2FGHIJKLMNOP2QR
5
6
35
40
46
40
0
0.83
0.23
0.83
0.71
(Cytochrom_B559)(Cytochrom_B559)_(Cytochrom_B559a)(Cytochrom _C550)(MSP)(Photo_RC)(PsbH)(PsbI)(PsbJ)(PsbK)(PsbL)(PsbM)(Ps bT)(PsbU)(PsbX)(PSII)(PSII_Ycf12)(Ycf9)
1
C1
ABCDE2FGHIJKLMNO2PQ
5
5
16
38
16
38
0
1.00
0.50
0.63
0.25
(C1-set)(MHC_I)_(C1-set)(V-set)_(C1-set)(V-set)_(DUF1968)(pe ptide)
1
C1
ABCDE
106
125
161
51
191
63
0
0.89
0.96
0.36
0.47
(Cytochrom_C)(peroxidase)
1
C1
AB
6
9
20
5
26
5
39
0.85
0.75
0
0.15
(Dehydratase_LU)(Dehydratase_MU)(Dehydratase_SU)
1
C1
ABC
5
6
13
6
15
6
5
1.00
0.08
0
0
(Dehydratase_LU)(Dehydratase_MU)(Dehydratase_SU)
4
C2
A2B2C2
5
6
13
6
15
6
5
1.00
1.00
1.00
1.00
(DNA_pol3_beta)_(DNA_pol3_beta_2)_(DNA_pol3_beta_3)(peptide)
1
C1
AB
16
25
24
8
38
12
25
0.94
0
0
0.13
(DNA_RNApol_7kD)(Elf1)(Histone)(Histone)_(Histone_H2A_C)(RNA _pol_A_bac)(RNA_pol_L_2)(RNA_POL_M_15KD)_(TFIIS_C)(RNA_pol_N )(RNA_pol_Rpb1_1)_(RNA_pol_Rpb1_2)_(RNA_pol_Rpb1_3)_(RNA_pol _Rpb1_4)_(RNA_pol_Rpb1_5[1-66])_(RNA_pol_Rpb1_6)_(RNA_pol_Rp b1_5[67-150])_(RNA_pol_Rpb1_7)_(RNA_pol_Rpb1_5[151-266])(RNA _pol_Rpb2_1[1-155])_(RNA_pol_Rpb2_2)_(RNA_pol_Rpb2_1[156-203 ])_(RNA_pol_Rpb2_3)_(RNA_pol_Rpb2_4)_(RNA_pol_Rpb2_5)_(RNA_p ol_Rpb2_6)_(RNA_pol_Rpb2_7)(RNA_pol_Rpb4)(RNA_pol_Rpb5_N)_(R NA_pol_Rpb5_C)(RNA_pol_Rpb6)(RNA_pol_Rpb8)(SHS2_Rpb7-N)_(S1) (Spt4)(Spt5_N)_(Spt5-NGN)_(KOW)_(DUF3912)_(CTD)(TAF)
1
unknown
ABC4D2EFGHIJKLMNOPQR2
5
5
5
20
5
20
0
1.00
1.00
0.40
1.00
(DNA_RNApol_7kD)(HTH_9)_(RNA_pol_Rpc82)(RNA_pol_3_Rpc31)(RNA _pol_L[1-30])_(RNA_pol_A_bac)_(RNA_pol_L[31-74])(RNA_pol_L_2 )(RNA_POL_M_15KD)_(TFIIS_C)(RNA_pol_N)(RNA_pol_Rpb1_1)_(RNA_ pol_Rpb1_2)_(RNA_pol_Rpb1_3)_(RNA_pol_Rpb1_4)_(RNA_pol_Rpb1_ 5)(RNA_pol_Rpb2_1[1-155])_(RNA_pol_Rpb2_2)_(RNA_pol_Rpb2_1[1 56-202])_(RNA_pol_Rpb2_3)_(RNA_pol_Rpb2_4)_(RNA_pol_Rpb2_5)_ (RNA_pol_Rpb2_6)_(RNA_pol_Rpb2_7)(RNA_pol_Rpb4)(RNA_pol_Rpb5 _N)_(RNA_pol_Rpb5_C)(RNA_pol_Rpb6)(RNA_pol_Rpb8)(RNA_pol_Rpc 34)(RNA_pol_Rpc4)(RPC5)_(RPC5_C)(SHS2_Rpb7-N)_(RNA_pol_Rbc25 )
1
C1
ABCDEFGHIJKLMNOPQ
9
9
9
17
9
17
1
1.00
1.00
1.00
1.00
(DNA_RNApol_7kD)(RNA_pol_A_bac)(RNA_pol_I_A49)(RNA_pol_I_TF) (RNA_pol_L_2)(RNA_POL_M_15KD)_(TFIIS_C)(RNA_pol_N)(RNA_pol_R pb1_1)_(RNA_pol_Rpb1_2)_(RNA_pol_Rpb1_3)_(RNA_pol_Rpb1_4)_(R NA_pol_Rpb1_5)(RNA_pol_Rpb2_1[2-155])_(RNA_pol_Rpb2_2)_(RNA_ pol_Rpb2_1[156-201])_(RNA_pol_Rpb2_3)_(RNA_pol_Rpa2_4)_(RNA_ pol_Rpb2_6)_(RNA_pol_Rpb2_7)(RNA_pol_Rpb5_N)_(RNA_pol_Rpb5_C )(RNA_pol_Rpb6)(RNA_pol_Rpb8)(RNA_polI_A14)(RNA_polI_A34)(RR N3)(Rrn6)(SHS2_Rpb7-N)_(RPA43_OB)(zf-RRN7)
1
C1
ABCDEFGHIJKLMNOPQR
9
9
9
18
9
18
0
1.00
1.00
1.00
0.89
(DNA_RNApol_7kD)(RNA_pol_A_bac)(RNA_pol_L_2)(RNA_POL_M_15KD) _(TFIIS_C)(RNA_pol_N)(RNA_pol_Rpb1_1)_(RNA_pol_Rpb1_2)_(RNA_ pol_Rpb1_3)_(RNA_pol_Rpb1_4)_(RNA_pol_Rpb1_5[1-66])_(RNA_pol _Rpb1_6)_(RNA_pol_Rpb1_5[67-150])_(RNA_pol_Rpb1_7)_(RNA_pol_ Rpb1_5[151-266])(RNA_pol_Rpb2_1[1-155])_(RNA_pol_Rpb2_2)_(RN A_pol_Rpb2_1[156-203])_(RNA_pol_Rpb2_3)_(RNA_pol_Rpb2_4)_(RN A_pol_Rpb2_5)_(RNA_pol_Rpb2_6)_(RNA_pol_Rpb2_7)(RNA_pol_Rpb4 )(RNA_pol_Rpb5_N)_(RNA_pol_Rpb5_C)(RNA_pol_Rpb6)(RNA_pol_Rpb 8)(SHS2_Rpb7-N)_(S1)
1
C1
ABCDEFGHIJKL
5
6
48
24
49
24
0
1.00
1.00
0.98
0.19
(DnaJ)_(Sec63)(Plug_translocon)_(SecY)(Sec61_beta)(Sec66)(Se cE)(TPR_1)
1
C1
ABCDEF
6
7
6
6
7
6
2
1.00
1.00
0.83
1.00
(DUF3585)(Ras)
1
C1
AB
5
6
6
5
7
6
32
1.00
1.00
1.00
0.83
(Dynein_light)(peptide)
1
C1
AB
11
13
22
5
24
5
0
0.84
0.14
0
0.14
(Dynein_light)(peptide)
2
C1
AB
11
13
22
5
24
5
0
0.84
0
0
0.14
(Ecotin)(Trypsin)
1
C1
AB
8
9
14
9
15
10
23
1.00
0.07
0
0
(Ecotin)(Trypsin)
2
C1
AB
8
9
14
9
15
10
23
1.00
0
0
0
(Ecotin)(Trypsin)
5
C2
A2B2
8
9
14
9
15
10
3
1.00
0.93
1.00
0.93
(EF-hand_7)(Lectin_leg-like)
1
C1
AB
6
6
9
2
9
2
79
1.00
1.00
0.22
1.00
(EF-hand_7)(peptide)
1
C1
AB
10
11
16
12
17
13
0
1.00
0.63
0.88
0.88
(EF-hand_7)_(EF-hand_7)(KCNQ_channel)
1
C1
AB
5
5
7
6
7
6
11
1.00
0.57
0.71
0.57
(EF-hand_7)(Lectin_leg-like)
5
C2
A2B2
5
6
8
2
9
2
79
0.83
0
0.88
0
(eIF-5_eIF-2B)(GTP_EFTU)_(GTP_EFTU_D2)_(eIF2_C)(Hexapep)(IF- 2B)(NTP_transferase)_(Hexapep)_(Hexapep)_(W2)(S1)_(LZ3wCH)_( EIF_2_alpha)
1
C1
ABCD3EF
6
6
6
8
6
8
100
1.00
0
0
0.50
(eIF-5_eIF-2B)(GTP_EFTU)_(GTP_EFTU_D2)_(eIF2_C)(Hexapep)(IF- 2B)(NTP_transferase)_(Hexapep)_(Hexapep)_(W2)(S1)_(LZ3wCH)_( EIF_2_alpha)
2
C2
A2B2C2D6E2F2
6
6
6
8
6
8
100
1.00
1.00
0.50
0.83
(Ephrin)(Ephrin_lbd)
1
C1
AB
10
10
10
11
10
11
27
1.00
0.80
0.90
0.90
(Ephrin)(HN)
1
C1
AB
8
8
8
9
8
9
26
1.00
0.88
1.00
0.75
(Ephrin_lbd)(peptide)
1
C1
AB
7
11
9
2
13
4
53
1.00
1.00
0.22
0.67
(EVA_Class_A)(IL8)
1
C1
AB
5
8
6
9
14
9
2
0.71
1.00
0.83
0.83
(Fas_alpha_ACP)_(FAS_I_H)_(KR)_(ketoacyl-synt)_(Ketoacyl-syn t_C)_(ACPS)(FAS_N)_(SAT)_(DUF1729)_(FAS_meander)_(MaoC_dehyd rat_N)_(MaoC_dehydratas)_(Acyl_transf_1)
1
C1
AB
6
8
7
3
9
3
100
0.85
0.29
0.29
0.43
(Fas_alpha_ACP)_(FAS_I_H)_(KR)_(ketoacyl-synt)_(Ketoacyl-syn t_C)_(ACPS)(FAS_N)_(SAT)_(DUF1729)_(FAS_meander)_(MaoC_dehyd rat_N)_(MaoC_dehydratas)_(Acyl_transf_1)
13
D3
A6B6
5
8
6
2
9
3
100
0.71
0.67
0.83
0.83
(F-box-like)(Skp1_POZ)_(Skp1)
1
C1
AB
5
5
5
4
5
4
9
1.00
0.60
0.80
0.60
(Fer4_7)(PsaA_PsaB)(PsaD)(PsaL)(PsaM)(PsaX)(PSI_8)(PSI_PsaE) (PSI_PsaF)(PSI_PsaJ)(PSI_PSAK)
1
C1
AB2CDEFGHIJK
7
7
12
12
12
12
0
1.00
0.42
0.42
0.08
(Fer4_7)(PsaA_PsaB)(PsaD)(PsaL)(PSI_PsaE)(PSI_PsaF)(PSI_PSAK )(peptide)
2
C1
AB2CDEFGH4
7
11
12
8
16
24
0
1.00
0.42
0.42
0.08
(Fer4_7)(PsaA_PsaB)(PsaD)(PsaL)(PsaM)(PsaX)(PSI_8)(PSI_PsaE) (PSI_PsaF)(PSI_PsaJ)(PSI_PSAK)
2
C3
A3B6C3D3E3F3G3H3I3J3K3
5
7
10
12
12
12
0
0.71
0.70
0.70
0.20
(Fer4_7)(PsaA_PsaB)(PsaD)(PsaL)(PSI_PsaE)(PSI_PsaF)(PSI_PSAK )(peptide)
3
C3
A3B6C3D3E3F3G3H12
5
11
10
8
16
24
0
0.71
0.70
0.70
0.20
(FERM_M)(Integrin_b_cyt)
1
C1
AB
5
5
6
5
6
5
0
1.00
0.50
0.33
1.00
(FERM_M)(peptide)
1
C1
AB
5
7
6
2
8
3
0
0.83
0.33
0.33
0.83
(FERM_N)_(FERM_M)_(FERM_C)(peptide)
1
C1
AB
6
14
6
3
14
6
0
0.75
1.00
0.50
1.00
(FHA)(peptide)
1
C1
AB
18
19
27
12
28
13
0
1.00
0.63
0.11
0.93
(Fib_alpha)(Fib_alpha)_(Fibrinogen_C)(peptide)
2
C1
AB2C2
7
12
13
3
23
6
0
0.70
0.77
0.31
0.31
(Fimbrial)(FimH_man-bind)_(Fimbrial)
1
C1
AB
8
8
10
8
10
8
50
1.00
1.00
1.00
1.00
(Fimbrial)(PapD_N)_(PapD_C)
1
C1
AB
8
10
10
11
12
11
14
0.80
0.90
1.00
0.60
(Fimbrial)(peptide)
1
C1
AB
5
5
6
2
6
2
17
1.00
1.00
1.00
0.33
(FimH_man-bind)_(Fimbrial)(peptide)
1
C1
AB
8
8
10
4
10
4
50
1.00
1.00
1.00
1.00
(FKBP_C)(Ins145_P3_rec)_(MIR)_(RYDR_ITPR)_(SPRY)_(RyR)_(RyR) _(SPRY)_(SPRY)_(RYDR_ITPR)_(RyR)_(RyR)_(RIH_assoc)_(EF-hand_ 7)_(RR_TM4-6)_(Ion_trans)
1
C1
AB
15
15
15
3
15
3
88
1.00
0
0.13
1.00
(FKBP_C)(Ins145_P3_rec)_(MIR)_(RYDR_ITPR)_(SPRY)_(RyR)_(RyR) _(SPRY)_(SPRY)_(RYDR_ITPR)_(RyR)_(RyR)_(RIH_assoc)_(RR_TM4-6 )_(Ion_trans)
1
C1
AB
37
37
37
3
37
3
79
1.00
0
0.03
1.00
(FKBP_C)(Ins145_P3_rec)_(MIR)_(RYDR_ITPR)_(SPRY)_(RyR)_(RyR) _(SPRY)_(RYDR_ITPR)_(RyR)_(RyR)_(RIH_assoc)_(RR_TM4-6)_(Ion_ trans)
1
C4
A4B4
6
6
6
1
6
1
100
1.00
1.00
0.33
1.00
(FKBP_C)(Ins145_P3_rec)_(MIR)_(RYDR_ITPR)_(SPRY)_(RyR)_(RyR) _(SPRY)_(SPRY)_(RYDR_ITPR)_(RyR)_(RyR)_(RIH_assoc)_(EF-hand_ 7)_(RR_TM4-6)_(Ion_trans)
2
C4
A4B4
15
15
15
3
15
3
88
1.00
1.00
0.60
1.00
(FKBP_C)(Ins145_P3_rec)_(MIR)_(RYDR_ITPR)_(SPRY)_(RyR)_(RyR) _(SPRY)_(SPRY)_(RYDR_ITPR)_(RyR)_(RyR)_(RIH_assoc)_(RR_TM4-6 )_(Ion_trans)
3
C4
A4B4
37
37
37
3
37
3
79
1.00
1.00
0.84
1.00
(Flavi_glycop_C)(V-set)_(V-set)
1
C1
AB
6
6
6
6
6
6
5
1.00
1.00
0.17
0
(Flavi_glycoprot)_(Flavi_glycop_C)(Flavi_M)
1
C1
AB
20
22
20
18
22
21
8
1.00
0
0.60
1.00
(Flavi_glycoprot)_(Flavi_glycop_C)(Flavi_propep)
1
C1
AB
5
5
5
7
5
7
12
1.00
0.20
0.20
0.80
(Flu_B_NS1)(ubiquitin)_(ubiquitin)
1
C1
AB
5
5
6
5
6
5
16
1.00
0.17
0
0
(Flu_B_NS1)(ubiquitin)_(ubiquitin)
2
C1
AB
5
5
6
5
6
5
65
1.00
0.17
0
0
(Flu_B_NS1)(ubiquitin)_(ubiquitin)
3
C1
AB
5
5
6
5
6
5
63
1.00
0
0
0
(Flu_B_NS1)(ubiquitin)_(ubiquitin)
6
C2
A2B2
5
5
6
5
6
5
5
1.00
0.67
0.67
0.83
(Flu_B_NS1)(ubiquitin)_(ubiquitin)
7
C2
A2B2
5
5
6
5
6
5
5
1.00
0
0
0
(Flu_NP)(peptide)
1
C1
AB
5
5
5
2
5
2
100
1.00
0.80
1.00
0.80
(Flu_PA)(Flu_PB1)(Flu_PB2)_(B)_(B)
1
C1
ABC
5
5
5
6
5
6
3
1.00
1.00
0.60
1.00
(fn1)_(fn1)(peptide)
1
C1
AB
9
9
9
1
9
1
0
1.00
0.89
0.67
0.44
(fn3)(HH_signal)
1
C1
AB
5
5
6
5
6
5
75
1.00
1.00
0.17
0.17
(Furin-like_2)(ZNRF_3_ecto)
1
C1
AB
7
7
7
5
7
5
9
1.00
0.29
0.14
0.43
(Furin-like_2)(ZNRF_3_ecto)
2
C2
A2B2
6
7
6
5
7
5
0
0.85
0.83
0.83
0.33
(Fusion_gly)(peptide)
1
C1
AB
8
9
15
7
16
8
0
1.00
0.07
0
0
(Fusion_gly)(peptide)
2
C3
A3B3
8
9
15
7
16
8
0
1.00
1.00
0
0.87
(CarbopepD_reg_2)_(Plug)_(TonB_dep_Rec)(SusD-like_3)_(SusD_R agB)
1
C1
AB
5
7
7
2
9
2
99
1.00
0.14
0.14
0.29
(CarbopepD_reg_2)_(Plug)_(TonB_dep_Rec)(SusD-like_3)_(SusD_R agB)
3
C2
A2B2
5
7
7
2
9
2
99
1.00
0.86
0.86
0.86
(G-alpha)(G-gamma)(Hormone_2)(HRM)_(7tm_2)(V-set)(WD40)_(WD4 0)_(WD40)_(WD40)_(WD40)_(WD40)
1
C1
ABCDEF
15
16
15
15
16
15
0
1.00
1.00
0.27
1.00
(G-alpha)(G-gamma)(HRM)_(7tm_2)(V-set)(WD40)_(WD40)_(WD40)_( WD40)_(WD40)_(WD40)(peptide)
1
C1
ABCDEF
17
26
17
11
26
13
0
1.00
1.00
0.29
1.00
(G-alpha)(G-gamma)(HRM)_(7tm_2)(V-set)(ZapB)_(WD40)_(WD40)_( WD40)_(WD40)_(WD40)_(WD40)
1
C1
ABCDE
6
7
6
7
7
8
2
1.00
1.00
0.33
1.00
(Claudin_2)(Ion_trans)_(Ion_trans)_(Ion_trans)_(Ion_trans)_( GPHH)_(Ca_chan_IQ)(VWA_N)_(VWA_3)_(VGCC_alpha2)
1
C1
ABC
5
8
5
3
8
3
100
1.00
1.00
0
1.00
(Chromo)(peptide)
1
C1
AB
34
35
49
22
50
22
8
0.97
0.73
0.53
0.61
(Gag_p24)_(Gag_p24_C)(Pro_isomerase)
1
C1
A12B
6
7
6
2
7
2
100
1.00
1.00
0
1.00
(G-alpha)(G-gamma)(Hormone_2)(HRM)_(7tm_2)(V-set)(ZapB)_(WD4 0)_(WD40)_(WD40)_(WD40)_(WD40)_(WD40)
1
C1
ABCDEF
16
16
16
21
16
21
0
1.00
1.00
0.38
0.94
(G-alpha)(G-gamma)(HRM)_(7tm_2)(Parathyroid)(V-set)(ZapB)_(W D40)_(WD40)_(WD40)_(WD40)_(WD40)_(WD40)
1
C1
ABCDEF
9
9
9
7
9
7
0
1.00
1.00
0.33
1.00
(G-alpha)(G-gamma)(HRM)_(7tm_2)(V-set)(WD40)_(WD40)_(WD40)_( WD40)_(WD40)_(WD40)
1
C1
ABCDE
5
5
5
4
5
4
1
1.00
1.00
0.60
1.00
(G-alpha)(G-gamma)(HRM)_(7tm_2)(V-set)(ZapB)_(WD40)_(WD40)_( WD40)_(WD40)_(WD40)_(WD40)(peptide)
1
C1
ABCDEF
28
28
28
22
28
22
0
1.00
1.00
0.36
0.96
(G-alpha)(G-gamma)(Phage_lysozyme)_(7tm_1)(V-set)_(V-set)(WD 40)_(WD40)_(WD40)_(WD40)_(WD40)_(WD40)
1
C1
ABCDE
7
7
7
10
7
10
3
1.00
1.00
0
1.00
(G-alpha)(peptide)
1
C1
AB
5
8
10
2
13
3
28
0.83
1.00
1.00
0.90
(G-alpha)(RGS)
1
C1
AB
9
9
9
11
9
11
11
1.00
1.00
1.00
0
(G-alpha)(RGS)
2
C1
AB
5
9
5
6
9
11
50
0.71
0
0
0
(G-alpha)(peptide)
4
C2
A2B2
5
8
10
2
13
3
28
0.83
0
0
0
(G-alpha)(RGS)
4
C2
A2B2
5
9
5
6
9
11
50
0.71
0
0
0.20
(GATase)(His_biosynth)
1
C1
AB
5
5
8
4
8
4
36
1.00
0.88
1.00
0.75
(GDNF)_(GDNF)(TGF_beta)
1
C1
AB
6
6
6
10
6
10
10
1.00
0
0
0
(GDNF)_(GDNF)(TGF_beta)
4
C2
A2B2
6
6
6
10
6
10
0
1.00
1.00
1.00
0.67
(COX1)(COX2-transmemb)_(COX2)(peptide)
1
C1
ABC
6
6
36
2
37
2
5
1.00
1.00
0.94
1.00
(Glycos_transf_2)_(Ricin_B_lectin)(peptide)
1
C1
AB
5
7
10
4
13
4
0
0.71
1.00
0.30
0.60
(GOLD_2)(P3A)
1
C1
AB
6
6
8
10
8
10
38
1.00
0.75
0.75
1.00
(GOLD_2)(peptide)
1
C1
AB
6
6
6
3
6
3
6
1.00
0.50
0.67
0.67
(GP120)(GP41)(ig)_(C2-set)(V-set)_(C1-set)
1
C1
ABCD2
5
5
5
3
5
3
7
1.00
0
0
1.00
(GP120)(GP41)(ig)_(C2-set)(V-set)_(C1-set)
2
C1
ABCD2
5
5
5
3
5
3
96
1.00
0
0
1.00
(GP120)(GP41)(ig)_(C2-set)(V-set)_(C1-set)
4
C3
A3B3C3D6
5
5
5
3
5
3
7
1.00
1.00
0
1.00
(GTP_EFTU)_(GTP_EFTU_D2)_(EFG_III)_(EFG_IV)_(EFG_C)(KH_2)_(R ibosomal_S3_C)(KOW)_(Ribosomal_L14e)(KOW)_(Ribosomal_L27e)(R ibosom_S12_S23)(Ribosomal_L1)(Ribosomal_L10)_(RL10P_insert)_ (Ribosomal_60s)(Ribosomal_L11_N)_(Ribosomal_L11)(Ribosomal_L 13)(Ribosomal_L13e)(Ribosomal_L14)(Ribosomal_L15e)(Ribosomal _L16)(Ribosomal_L18)(Ribosomal_L18A)(Ribosomal_L19e)(Ribosom al_L2)_(Ribosomal_L2_C)(Ribosomal_L21e)(Ribosomal_L22)(Ribos omal_L22e)(Ribosomal_L23eN)_(Ribosomal_L23)(Ribosomal_L24e)( Ribosomal_L26[1-43])_(KOW)_(Ribosomal_L26[44-82])(Ribosomal_ L27A)(Ribosomal_L29)(Ribosomal_L29e)(Ribosomal_L3)(Ribosomal _L30_N)_(Ribosomal_L30)(Ribosomal_L31e)(Ribosomal_L32e)(Ribo somal_L34e)(Ribosomal_L35Ae)(Ribosomal_L36e)(Ribosomal_L37ae )(Ribosomal_L37e)(Ribosomal_L38e)(Ribosomal_L39)(Ribosomal_L 4)_(Ribos_L4_asso_C)(Ribosomal_L41)(Ribosomal_L44)(Ribosomal _L5)_(Ribosomal_L5_C)(Ribosomal_L5e)_(Ribosomal_L18_c)(Ribos omal_L6)_(Ribosomal_L6)(Ribosomal_L6e)(Ribosomal_L7Ae)(Ribos omal_S10)(Ribosomal_S11)(Ribosomal_S13)(Ribosomal_S13_N)_(Ri bosomal_S15)(Ribosomal_S14)(Ribosomal_S17_N)_(Ribosomal_S17) (Ribosomal_S17e)(Ribosomal_S19)(Ribosomal_S19e)(Ribosomal_S2 )(Ribosomal_S21e)(Ribosomal_S24e)(Ribosomal_S25)(Ribosomal_S 26e)(Ribosomal_S27e)(Ribosomal_S28e)(Ribosomal_S30)(Ribosoma l_S3Ae)(Ribosomal_S5)_(Ribosomal_S5_C)(Ribosomal_S6e)(Riboso mal_S7)(Ribosomal_S7e)(Ribosomal_S8)(Ribosomal_S8e)(Ribosoma l_S9)(RS4NT)_(S4)_(Ribosomal_S4e)_(KOW)_(40S_S4_C)(S10_plect in)(S4)(ubiquitin)_(Ribosomal_L40e)(ubiquitin)_(Ribosomal_S2 7)(WD40)_(WD40)_(WD40)_(WD40)_(WD40)_(WD40)_(WD40)
1
C1
ABCDEFGHIJKLMNOPQRSTUVWXYZabcdefghijklmnopqrs3tuvwxyz0123456789(AA)(AB)(AC)(AD)(AE)(AF)(AG)(AH)(AI)(AJ)(AK)(AL)(AM)(AN)
5
5
5
78
5
78
0
1.00
1.00
1.00
1.00
(GTP_EFTU)_(GTP_EFTU_D2)_(EFG_III)_(EFG_IV)_(EFG_C)(KH_2)_(R ibosomal_S3_C)(KOW)_(Ribosomal_L14e)(KOW)_(Ribosomal_L27e)(R ibosom_S12_S23)(Ribosomal_L1)(Ribosomal_L10)_(RL10P_insert)_ (Ribosomal_60s)(Ribosomal_L11_N)_(Ribosomal_L11)(Ribosomal_L 13)(Ribosomal_L13e)(Ribosomal_L14)(Ribosomal_L15e)(Ribosomal _L16)(Ribosomal_L18)(Ribosomal_L18A)(Ribosomal_L19e)(Ribosom al_L2)_(Ribosomal_L2_C)(Ribosomal_L21e)(Ribosomal_L22)(Ribos omal_L22e)(Ribosomal_L23eN)_(Ribosomal_L23)(Ribosomal_L24e)( Ribosomal_L26[1-43])_(KOW)_(Ribosomal_L26[44-82])(Ribosomal_ L27A)(Ribosomal_L29)(Ribosomal_L29e)(Ribosomal_L3)(Ribosomal _L30_N)_(Ribosomal_L30)(Ribosomal_L31e)(Ribosomal_L32e)(Ribo somal_L34e)(Ribosomal_L35Ae)(Ribosomal_L36e)(Ribosomal_L37ae )(Ribosomal_L37e)(Ribosomal_L38e)(Ribosomal_L39)(Ribosomal_L 4)_(Ribos_L4_asso_C)(Ribosomal_L44)(Ribosomal_L5)_(Ribosomal _L5_C)(Ribosomal_L5e)_(Ribosomal_L18_c)(Ribosomal_L6)_(Ribos omal_L6)(Ribosomal_L6e)(Ribosomal_L7Ae)(Ribosomal_S10)(Ribos omal_S11)(Ribosomal_S13)(Ribosomal_S13_N)_(Ribosomal_S15)(Ri bosomal_S14)(Ribosomal_S17_N)_(Ribosomal_S17)(Ribosomal_S17e )(Ribosomal_S19)(Ribosomal_S19e)(Ribosomal_S2)(Ribosomal_S21 e)(Ribosomal_S24e)(Ribosomal_S25)(Ribosomal_S26e)(Ribosomal_ S27e)(Ribosomal_S28e)(Ribosomal_S30)(Ribosomal_S3Ae)(Ribosom al_S5)_(Ribosomal_S5_C)(Ribosomal_S6e)(Ribosomal_S7)(Ribosom al_S7e)(Ribosomal_S8)(Ribosomal_S8e)(Ribosomal_S9)(RS4NT)_(S 4)_(Ribosomal_S4e)_(KOW)_(40S_S4_C)(S10_plectin)(S4)(ubiquit in)_(Ribosomal_L40e)(ubiquitin)_(Ribosomal_S27)(WD40)_(WD40) _(WD40)_(WD40)_(WD40)_(WD40)_(WD40)(peptide)
1
C1
ABCDEFGHIJKLMNOPQRSTUVWXYZabcdefghijklmnopqr3stuvwxyz0123456789(AA)(AB)(AC)(AD)(AE)(AF)(AG)(AH)(AI)(AJ)(AK)(AL)(AM)(AN)
5
5
5
77
5
77
100
1.00
1.00
1.00
1.00
(GTP_EFTU)_(GTP_EFTU_D2)_(GTP_EFTU_D3)(peptide)
1
C1
AB
6
9
7
2
10
3
58
0.75
1.00
1.00
0.57
(Guanylate_kin)(peptide)
1
C1
AB
5
6
5
1
6
1
7
1.00
1.00
0.80
0.80
(HAV_VP)(Rhv)
1
C1
AB2
6
7
6
5
7
5
8
1.00
1.00
0.33
0.67
(Cystatin)(Peptidase_C1)
1
C1
AB
5
6
5
8
6
9
12
1.00
1.00
1.00
1.00
(CytoC_RC)(Photo_RC)(PRCH)_(PRC)
1
C1
AB2C
9
9
37
5
37
5
4
1.00
1.00
1.00
0.57
(Herpes_glycop_D)_(Ig_3)(MFS_1)
1
C1
AB
5
5
5
2
5
2
100
1.00
1.00
0
1.00
(Herpes_U34)(Herpes_UL31)
1
C1
AB
7
7
7
11
7
11
11
1.00
0.86
0.57
0.57
(Hist_deacetyl)(peptide)
1
C1
AB
9
10
21
4
25
5
21
1.00
1.00
0.86
0.81
(Histone)(Histone)_(Histone_H2A_C)
1
C1
AB
6
7
6
12
7
16
17
1.00
0.50
0.83
1.00
(Histone)(PHD)_(Bromodomain)
1
C1
AB
13
15
15
9
17
9
0
1.00
0.93
0.53
0.80
(Histone)(PHD)_(PHD)
1
C1
AB
7
8
14
6
15
6
0
1.00
0.93
0.86
0.86
(Histone)(Pre-SET)_(SET)
1
C1
AB
5
5
8
4
8
4
32
1.00
0.50
0.13
0.13
(Histone)(SIR2)
1
C1
AB
8
9
13
10
14
11
14
0.88
1.00
0.62
0.92
(Histone)(YEATS)
1
C1
AB
10
13
17
8
20
11
15
1.00
0.76
0.35
0.59
(Histone)(Histone)_(Histone_H2A_C)(SNF2-rel_dom)_(Helicase_C )_(SnAC)(TAF)
1
unknown
A4B2CD2
5
6
5
5
6
5
15
1.00
1.00
0
1.00
(H-K_ATPase_N)_(Cation_ATPase_N)_(E1-E2_ATPase)_(Cation_ATPa se)_(Cation_ATPase_C)(Na_K-ATPase)
1
C1
AB
8
8
12
2
12
2
100
1.00
1.00
0.75
1.00
(RuBisCO_large_N)_(RuBisCO_large)(RuBisCO_small)
1
C1
AB
17
23
56
38
62
48
10
1.00
0.02
0
0.11
(RuBisCO_large_N)_(RuBisCO_large)(RuBisCO_small)
2
C1
AB
17
23
56
38
62
48
10
1.00
0
0
0.11
(RuBisCO_large_N)_(RuBisCO_large)(RuBisCO_small)
3
C1
AB
16
23
55
37
62
48
3
0.93
0
0
0.09
(RuBisCO_large_N)_(RuBisCO_large)(RuBisCO_small)
4
C1
AB
5
23
10
14
62
48
11
1.00
0
0
0
(Hormone_2)(HRM)
1
C1
AB
5
6
11
5
12
7
4
1.00
1.00
0.09
0.64
(DNA_pol3_beta)_(DNA_pol3_beta_2)_(DNA_pol3_beta_3)(peptide)
2
C2
A2B2
17
25
26
9
38
12
25
0.94
1.00
0.46
0.81
(DNA_RNApol_7kD)(HTH_9)_(RNA_pol_Rpc82)_(TFIIE_alpha)(RNA_po l_3_Rpc31)(RNA_pol_A_bac)(RNA_pol_L_2)(RNA_POL_M_15KD)_(TFII S_C)(RNA_pol_N)(RNA_pol_Rpb1_1)_(RNA_pol_Rpb1_2)_(RNA_pol_Rp b1_3)_(RNA_pol_Rpb1_4)_(RNA_pol_Rpb1_5)(RNA_pol_Rpb2_1[1-155 ])_(RNA_pol_Rpb2_2)_(RNA_pol_Rpb2_1[156-203])_(RNA_pol_Rpb2_ 3)_(RNA_pol_Rpb2_4)_(RNA_pol_Rpb2_6)_(RNA_pol_Rpb2_7)(RNA_po l_Rpb4)(RNA_pol_Rpb5_N)_(RNA_pol_Rpb5_C)(RNA_pol_Rpb6)(RNA_p ol_Rpb8)(RNA_pol_Rpc34)(RNA_pol_Rpc4)(RPC5)(SHS2_Rpb7-N)_(RN A_pol_Rbc25)
1
C1
ABCDEFGHIJKLMNOPQ
9
10
9
17
10
17
0
1.00
1.00
1.00
1.00
(DUF3364)_(Oxidored_nitro)(Oxidored_nitro)
1
C1
AB
10
17
43
7
53
8
15
0.83
0
0
0.07
(DUF3364)_(Oxidored_nitro)(Oxidored_nitro)
2
C1
AB
10
17
43
7
53
8
51
0.83
0
0
0.07
(DUF3364)_(Oxidored_nitro)(Oxidored_nitro)
11
C2
A2B2
10
17
43
7
53
8
11
0.83
1.00
1.00
0.98
(DUF4927)(Hormone_recep)
1
C1
AB
40
43
137
17
144
21
0
0.97
0.97
0.73
0.74
(Hpt)(Response_reg)
1
C1
AB
5
6
7
7
8
9
10
1.00
1.00
0.71
0.71
(HTH_SUN2)_(Sad1_UNC)(peptide)
1
C1
AB
5
5
9
2
9
2
5
1.00
0
0.22
0
(HTH_SUN2)_(Sad1_UNC)(peptide)
10
C3
A3B3
5
5
9
2
9
2
0
1.00
0.67
0.33
0.78
(E1_dh)(Transket_pyr)_(Transketolase_C)
1
C1
AB
7
8
33
6
34
6
6
0.87
0
0
0
(E1_dh)(Transket_pyr)_(Transketolase_C)
2
C1
AB
7
8
33
6
34
6
6
0.87
0
0
0
(E1_dh)(Transket_pyr)_(Transketolase_C)
5
C2
A2B2
8
8
34
6
34
6
5
1.00
1.00
0.97
1.00
(IF-2B)(NTP_transferase)_(Hexapep)_(Hexapep)(NTP_transferase )_(Hexapep)_(Hexapep)_(W2)
1
C1
A3BC
8
8
8
10
8
10
7
1.00
0
0
0.75
(IF-2B)(NTP_transferase)_(Hexapep)_(Hexapep)(NTP_transferase )_(Hexapep)_(Hexapep)_(W2)
2
C2
A6B2C2
8
8
8
10
8
10
7
1.00
1.00
0.88
1.00
(EF-hand_7)_(EF-hand_7)(peptide)
1
C1
AB
41
69
74
12
121
17
0
0.74
0.77
0.89
0.78
(Ig_3)_(C1-set)(V-set)_(C1-set)
1
C1
AB
7
7
7
2
7
2
15
1.00
1.00
1.00
1.00
(EGF)_(FXa_inhibition)(Trypsin)
2
C1
AB
6
7
26
1
27
2
8
1.00
0
0
0
(EGF)_(FXa_inhibition)(Trypsin)
1
C1
AB
7
7
27
2
27
2
39
1.00
1.00
1.00
0.81
(INCENP_ARK-bind)(Pkinase)
1
C1
AB
5
5
15
5
15
5
0
1.00
1.00
0.93
0.93
(Inhibitor_I42)(Peptidase_C1)
1
C1
AB
6
6
6
6
6
6
26
1.00
1.00
1.00
0.50
(Inhibitor_Mig-6)(PK_Tyr_Ser-Thr)
1
C1
AB
5
5
5
2
5
2
98
1.00
1.00
0.60
0.80
(F_actin_cap_B)(F-actin_cap_A)(peptide)
1
C1
ABC
6
6
10
2
10
2
0
1.00
1.00
0.90
1.00
(F_actin_cap_B)(F-actin_cap_A)(peptide)
2
C1
ABC
5
6
9
2
10
2
8
0.83
0
0
0
(F_actin_cap_B)(F-actin_cap_A)(peptide)
3
C1
ABC
5
6
9
2
10
2
8
0.83
0
0
0
(IRK)_(IRK_C)(MTABC_N)_(ABC_membrane)_(ABC_tran)_(ABC_membra ne)_(ABC_tran)
1
C1
AB
13
13
13
4
13
4
99
1.00
0
0
1.00
(IRK)_(IRK_C)(MTABC_N)_(ABC_membrane)_(ABC_tran)_(ABC_membra ne)_(ABC_tran)
2
C1
AB
11
13
11
4
13
4
99
0.84
0
0
1.00
(IRK)_(IRK_C)(MTABC_N)_(ABC_membrane)_(ABC_tran)_(ABC_membra ne)_(ABC_tran)
3
C2
A2B2
12
13
12
4
13
4
99
0.92
0
0
1.00
(IRK)_(IRK_C)(MTABC_N)_(ABC_membrane)_(ABC_tran)_(ABC_membra ne)_(ABC_tran)
6
C4
A4B4
13
13
13
4
13
4
99
1.00
1.00
0
1.00
(ITAM)(SH2)_(SH2)
1
C1
AB
5
5
5
6
5
6
0
1.00
1.00
1.00
1.00
(JAB)(ubiquitin)
1
C1
AB
5
7
9
6
11
7
21
0.71
1.00
0.78
0.67
(Kinesin)(Tubulin)_(Tubulin_C)
1
C1
AB2
69
81
69
36
81
37
2
0.87
0.91
0.30
1.00
(Ku_N)_(Ku)_(Ku_C)_(Ku_PK_bind)(Ku_N)_(Ku)_(Ku_C)_(SAP)(NUC1 94)_(DNAPKcs_CC5)_(FAT)_(PI3_PI4_kinase)_(FATC)
1
C1
ABC
5
8
5
3
8
3
100
1.00
1.00
0
1.00
(KH_2)_(Ribosomal_S3_C)(KOW)_(Ribosomal_L14e)(KOW)_(Ribosoma l_L27e)(Ribosom_S12_S23)(Ribosomal_L13)(Ribosomal_L13e)(Ribo somal_L14)(Ribosomal_L15e)(Ribosomal_L16)(Ribosomal_L18)(Rib osomal_L18A)(Ribosomal_L19e)(Ribosomal_L2)_(Ribosomal_L2_C)( Ribosomal_L21e)(Ribosomal_L22)(Ribosomal_L22e)(Ribosomal_L23 eN)_(Ribosomal_L23)(Ribosomal_L24e)(Ribosomal_L26)(Ribosomal _L27A)(Ribosomal_L28e)(Ribosomal_L29)(Ribosomal_L29e)(Riboso mal_L3)(Ribosomal_L30_N)_(Ribosomal_L30)(Ribosomal_L31e)(Rib osomal_L32e)(Ribosomal_L34e)(Ribosomal_L35Ae)(Ribosomal_L36e )(Ribosomal_L37ae)(Ribosomal_L37e)(Ribosomal_L38e)(Ribosomal _L4)_(Ribos_L4_asso_C)(Ribosomal_L44)(Ribosomal_L5)_(Ribosom al_L5_C)(Ribosomal_L5e)_(Ribosomal_L18_c)(Ribosomal_L6)_(Rib osomal_L6)(Ribosomal_L6e_N)_(Ribosomal_L6e)(Ribosomal_L7Ae)( Ribosomal_S10)(Ribosomal_S11)(Ribosomal_S13)(Ribosomal_S13_N )_(Ribosomal_S15)(Ribosomal_S14)(Ribosomal_S17_N)_(Ribosomal _S17)(Ribosomal_S17e)(Ribosomal_S19)(Ribosomal_S19e)(Ribosom al_S2)_(40S_SA_C)(Ribosomal_S21e)(Ribosomal_S24e)(Ribosomal_ S25)(Ribosomal_S26e)(Ribosomal_S27)(Ribosomal_S27e)(Ribosoma l_S28e)(Ribosomal_S30)(Ribosomal_S3Ae)(Ribosomal_S5)_(Riboso mal_S5_C)(Ribosomal_S6e)(Ribosomal_S7)(Ribosomal_S7e)(Riboso mal_S8)(Ribosomal_S8e)(Ribosomal_S9)(RS4NT)_(S4)_(Ribosomal_ S4e)_(KOW)_(40S_S4_C)(S10_plectin)(S4)(WD40)_(WD40)_(WD40)_( WD40)_(WD40)_(WD40)_(WD40)(peptide)
1
C1
ABCDEFGHIJKLMNOPQRSTUVWXYZabcdefghijklmn3opqrstuvwxyz0123456789(AA)(AB)(AC)(AD)(AE)(AF)(AG)(AH)(AI)4
6
6
6
73
6
73
9
1.00
1.00
1.00
1.00
(Flavi_glycop_C)(V-set)_(C1-set)
1
C1
AB2
5
17
5
4
18
14
6
1.00
1.00
0
0.20
(Flavi_NS2B)(Peptidase_S7)
1
C1
AB
9
9
31
11
43
11
0
1.00
0.97
0.87
0.81
(Flu_PA)(Flu_PB1)(Flu_PB2)
1
C1
ABC
34
45
40
26
51
29
3
1.00
0.95
0.78
0.85
(F-protein)(SH3_1)
1
C1
AB
6
7
7
6
9
6
49
1.00
0.86
0.29
0.43
(LAMTOR)(LAMTOR5)(MAPKK1_Int)(Robl_LC7)
1
C1
ABCD2
5
5
5
6
5
6
3
1.00
1.00
0.20
0.40
(Lectin_legB)(peptide)
1
C1
AB
6
8
12
4
16
8
38
1.00
0.58
0.25
0.17
(LON_substr_bdg)_(Yippee-Mis18)(MMS1_N)_(CPSF_A)
1
C1
AB
10
10
12
3
14
3
84
1.00
1.00
1.00
0.75
(LRR_RI_capping)_(LRR_6)_(LRR_6)(RnaseA)
1
C1
AB
5
5
6
8
6
8
28
1.00
0.50
0.83
0.67
(Lys)(tRNA_anti-codon)
1
C1
AB
5
5
5
2
5
2
88
1.00
1.00
1.00
0
(M11L)(peptide)
1
C1
AB
12
12
13
6
13
6
5
1.00
0.31
0.23
0.31
(MaoC_dehydrat_N)(MaoC_dehydratas)
6
C2
A2B2
5
6
8
9
9
10
8
1.00
1.00
0.50
0.50
(MATH)(peptide)
32
C3
A3B3
5
23
9
2
45
8
1
0.83
1.00
0
0.67
(MazE_antitoxin)(PIN)
1
C1
AB
5
9
5
8
9
12
21
0.83
0
0
0
(MazE_antitoxin)(PIN)
3
C2
A2B2
6
9
6
10
9
12
5
0.75
0.33
0
0.33
(MazE_antitoxin)(PIN)
4
C2
A2B2
5
9
5
8
9
12
5
0.83
0
0
0
(MazE_antitoxin)(PIN)
6
D2
A4B4
6
9
6
8
9
12
5
0.85
1.00
0.67
0.83
(Metallophos_2)(Vps35)
1
C1
AB
6
6
6
6
6
6
41
1.00
0.33
0.17
0.67
(Methyltransf_PK)(peptide)
1
C1
AB
8
8
18
3
18
3
33
1.00
0.89
0.28
0.72
(MHC_II_alpha)_(C1-set)(MHC_II_beta)_(C1-set)(MHC2-interact)
1
C1
ABC
10
11
11
7
12
8
0
1.00
1.00
0
0.45
(MIF4G)_(MIF4G_like)_(MIF4G_like_2)(RRM_1)
1
C1
AB
7
7
8
2
8
2
100
1.00
1.00
0.75
1.00
(MIT)(peptide)
1
C1
AB
5
11
6
5
13
8
0
0.83
0.83
0.83
0.67
(MIT)(peptide)
2
C1
AB
5
11
6
4
13
8
0
0.71
0.83
0.67
0.83
(MM_CoA_mutase)(MM_CoA_mutase)_(B12-binding)
1
C1
AB
5
5
10
4
10
4
31
1.00
1.00
1.00
1.00
(MoaE)(ThiS)
1
C1
AB
8
8
10
12
10
12
15
1.00
0.30
0
0
(MoaE)(ThiS)
3
C2
A2B2
8
8
10
12
10
12
15
1.00
1.00
1.00
1.00
(Motile_Sperm)(peptide)
1
C1
AB
6
6
6
4
6
4
0
1.00
0.67
0.50
0.83
(MT)(Tubulin)_(Tubulin_C)
1
C1
AB2
6
7
6
8
7
9
39
1.00
1.00
0.50
1.00
(MTS)(Trm112p)
1
C1
AB
5
5
8
3
8
3
12
1.00
1.00
1.00
0.63
(GP41)(V-set)_(C1-set)(V-set_2)_(C1-set)
1
C1
ABC
13
16
21
5
24
7
0
0.88
1.00
0.05
0.71
(GP41)(V-set)_(C1-set)(V-set_2)_(C1-set)
2
C1
ABC
9
16
17
4
24
7
7
0.75
0.06
0.06
0.12
(Neur_chan_LBD)(peptide)
1
C1
AB
9
11
11
3
14
3
19
0.90
0.09
0
0.09
(Neur_chan_LBD)(peptide)
2
C1
AB
8
11
10
2
14
3
34
0.88
0
0
0
(Neur_chan_LBD)(Toxin_8)
1
C1
AB
8
9
10
9
12
10
19
0.88
0.10
0
0.10
(Neur_chan_LBD)(Toxin_8)
2
C1
AB
7
9
9
7
12
10
34
0.87
0
0
0
(Neur_chan_LBD)(Toxin_TOLIP)
1
C1
AB
5
5
13
9
13
9
8
1.00
0.85
0
0.85
(Neur_chan_LBD)_(Neur_chan_memb)(SabA_adhesion)
1
C1
A5B
5
6
5
4
6
5
34
1.00
1.00
0
1.00
(Neur_chan_LBD)(Neur_chan_LBD)_(Neur_chan_memb)(V-set)_(C1-s et)(V-set)_(C1-set)_(C1-set)_(C1-set)
1
C1
A3B2C2D2
11
12
11
3
12
3
43
1.00
1.00
0
1.00
(Neur_chan_LBD)(peptide)
3
C5
A5B5
8
11
10
2
14
3
0
0.88
1.00
0
0.80
(Neur_chan_LBD)(Toxin_8)
3
C5
A5B5
7
9
9
7
12
10
11
0.87
1.00
0
0.78
(GP41)(V-set)_(C1-set)
1
C1
AB2
15
23
31
11
41
15
0
0.73
0.94
0.06
0.71
(NusA_N)_(KH_5)_(HHH_5)(Rho_N)_(Rho_RNA_bind)_(ATP-synt_ab)( RNA_pol_L[1-30])_(RNA_pol_A_bac)_(RNA_pol_L[31-74])_(RNA_pol _A_CTD)(RNA_pol_Rpb1_1)_(RNA_pol_Rpb1_2)_(RNA_pol_Rpb1_3)_(R NA_pol_Rpb1_4)_(RNA_pol_Rpb1_5)(RNA_pol_Rpb2_1[1-155])_(RNA_ pol_Rpb2_2)_(RNA_pol_Rpb2_1[156-203])_(RNA_pol_Rpb2_2)_(RNA_ pol_Rpb2_3)_(RNA_pol_Rpb2_45)_(RNA_pol_Rpb2_6)_(RNA_pol_Rpb2 _7)(RNA_pol_Rpb6)
1
unknown
AB6C2DEF
5
7
5
6
7
10
100
1.00
1.00
0
1.00
(OTU)(ubiquitin)
1
C1
AB
15
17
15
16
17
16
7
1.00
1.00
0.87
0.73
(PABP)(PAM2)
1
C1
AB
5
5
9
7
9
7
0
1.00
0.78
1.00
0.44
(PABP)(peptide)
1
C1
AB
12
12
16
3
16
3
0
1.00
0.81
1.00
0.50
(Pacifastin_I)(Trypsin)
1
C1
AB
5
5
5
7
5
7
34
1.00
1.00
1.00
0.80
(HCV_NS1)(V-set)_(C1-set)
1
C1
AB2
14
31
16
6
34
17
0
0.73
0.94
0
0.75
(HCV_NS1)(V-set)_(C1-set)
3
C1
AB2
6
31
6
5
34
17
28
1.00
1.00
0.67
0.83
(PBD)(Ras)
1
C1
AB
5
5
5
8
7
10
30
1.00
0.80
0.80
0.20
(PDZ)(peptide)
1
C1
AB
63
82
126
44
151
54
0
0.88
0.87
0.71
0.70
(PDZ_assoc)_(PDZ)(peptide)
1
C1
AB
5
5
14
3
14
3
78
1.00
1.00
0.79
0.79
(Pep_deformylase)(peptide)
1
C1
AB
6
6
9
6
9
6
26
1.00
0.89
0.67
0.78
(Peptidase_C12)(ubiquitin)
1
C1
AB
5
7
7
6
9
7
8
0.71
0.86
1.00
0.86
(Peptidase_C65)(ubiquitin)
1
C1
AB
7
7
8
10
8
10
9
1.00
1.00
1.00
0.63
(Peptidase_M10)(peptide)
1
C1
AB
12
12
17
8
18
8
11
1.00
1.00
0.59
0.82
(Peptidase_M10)(TIMP)
1
C1
AB
9
9
13
8
13
8
12
1.00
1.00
0.92
0.92
(Peptidase_M16)_(Peptidase_M16_C)_(Peptidase_M16_M)_(Peptida se_M16_C)(peptide)
1
C1
AB
9
11
18
2
22
2
0
0.90
0.89
0.50
0.89
(Peptidase_M16)_(Peptidase_M16_C)_(Peptidase_M16_M)_(Peptida se_M16_C)(peptide)
3
C2
A2B2
9
11
18
2
22
2
0
0.90
0
0
0.06
(Peptidase_S9_N)_(Peptidase_S9)(peptide)
1
C1
AB
6
11
12
2
22
6
0
1.00
0.92
0.58
0.92
(PH_TFIIH)(peptide)
1
C1
AB
5
5
9
2
10
2
4
1.00
0
0.44
1.00
(PHD)_(Bromodomain)(peptide)
1
C1
AB
13
17
15
7
19
7
0
0.86
0.93
0.53
0.80
(PHD)_(PHD)(peptide)
1
C1
AB
9
10
17
3
18
3
0
1.00
0.82
0.88
0.88
(Phlebovirus_G1)(Phlebovirus_G2)_(Phlebo_G2_C)
1
C1
AB
5
6
5
3
6
5
100
1.00
0
0.60
0
(PID)(peptide)
1
C1
AB
14
15
21
11
22
11
7
0.93
0.76
0.81
0.48
(PK_Tyr_Ser-Thr)(peptide)
1
C1
AB
8
13
17
6
23
8
30
0.80
0.88
0.35
0.76
(Pkinase)_(Pkinase_C)(peptide)
1
C1
AB
7
8
23
3
24
4
0
1.00
1.00
0.30
0.96
(Plexin_cytopl)(Ras)
1
C1
AB
6
7
6
7
7
9
39
1.00
0.83
0.50
0.33
(Plug_translocon)_(SecY)(SecE)(peptide)
1
C1
ABC
6
8
6
4
8
4
4
0.85
1.00
0.17
1.00
(Porin_3)(Tom22)(Tom5)(TOM6p)(Tom7)
1
C1
ABCDE
5
5
5
5
5
5
100
1.00
0
0
1.00
(Porin_3)(Tom22)(Tom5)(TOM6p)(Tom7)
2
C1
ABCDE
5
5
5
5
5
5
100
1.00
0
0
1.00
(Porin_3)(Tom22)(Tom5)(TOM6p)(Tom7)
3
C2
A2B2C2D2E2
5
5
5
5
5
5
100
1.00
1.00
0
1.00
(potato_inhibit)(Trypsin)
1
C1
AB
5
5
7
5
7
5
26
1.00
0.86
1.00
0.86
(PRELI)(UPF0203)
1
C1
AB
6
7
7
4
8
4
31
1.00
0.43
0.29
0.29
(PRELI)(UPF0203)
3
C2
A2B2
5
7
5
4
8
4
8
0.83
0.80
1.00
0.60
(Pre-SET)_(SET)(peptide)
1
C1
AB
7
7
11
3
12
3
32
1.00
0.64
0.09
0.09
(Pre-SET)_(SET)(peptide)
2
C2
A2B2
6
7
10
2
12
3
77
1.00
0.80
1.00
1.00
(V-set)_(C1-set)(V-set)_(DUF1968)
1
C1
AB
65
67
102
24
108
25
8
1.00
1.00
0.80
0.86
(Profilin)(peptide)
1
C1
AB
6
8
6
5
8
5
0
1.00
0.83
0
1.00
(Proteasome)(Proteasome_A_N)_(Proteasome)
1
C1
AB
11
14
11
8
14
22
36
0.84
0
0
0.55
(Proteasome)(Proteasome_A_N)_(Proteasome)
2
C1
AB
11
14
11
8
14
22
14
0.84
0
0
0.55
(Proteasome)(Proteasome_A_N)_(Proteasome)
3
D7
A14B14
12
14
12
8
14
22
14
0.92
1.00
0
0.67
(Proteasome)(Proteasome_A_N)_(Proteasome)
4
C2
A2B2
10
14
10
8
14
22
36
0.76
0
0
0.60
(Proteasome)(Proteasome_A_N)_(Proteasome)
5
C2
A2B2
10
14
10
8
14
22
14
0.76
0
0
0.60
(Proteasome)(Proteasome_A_N)_(Proteasome)
6
C2
A2B2
10
14
10
8
14
22
36
0.76
0
0
0.60
(Proteasome)(Proteasome_A_N)_(Proteasome)
7
C2
A2B2
10
14
10
8
14
22
14
0.76
0
0
0.60
(Proteasome)(Proteasome_A_N)_(Proteasome)
8
C7
A7B7
11
14
11
8
14
22
14
0.84
0.09
0.27
0.64
(PTR2)(peptide)
1
C1
AB
5
5
7
4
7
4
12
1.00
1.00
0.71
0.57
(PWWP)(peptide)
1
C1
AB
5
6
6
3
7
3
18
1.00
1.00
0.83
0.83
(Rad60-SLD)(UQ_con)
1
C1
AB
6
8
6
8
8
9
13
1.00
0.67
0
0.17
(RA)(Ras)
1
C1
AB
6
6
6
8
6
8
15
1.00
0.67
0.17
0.50
(HRM)(peptide)
1
C1
AB
7
12
12
3
20
7
4
1.00
0.92
0.08
0.58
(Ras)(peptide)
3
C1
AB
5
23
10
2
40
9
4
0.83
0
0
0
(Ras)(peptide)
1
C1
AB
7
23
7
3
40
9
6
1.00
0.71
0.86
0.43
(RAG1_imp_bd)_(zf-C3HC4)_(zf-RAG1)_(RAG1)(RAG2)_(RAG2_PHD)
2
C1
A2B2
7
8
7
4
8
4
53
0.87
1.00
0.29
1.00
(RAG2)_(RAG2_PHD)(SBP_bac_1)_(zf-C3HC4)_(zf-RAG1)_(RAG1)
2
C1
A2B2
11
11
11
2
11
2
100
1.00
1.00
0.18
1.00
(Ran_BP1)(Ras)
1
C1
AB
8
8
8
3
8
3
21
1.00
1.00
0.88
0.88
(Ras)(peptide)
11
C2
A2B2
5
23
16
1
40
9
24
1.00
0
0
0
(Ras)(RBD-FIP)
1
C1
AB
6
6
7
6
7
6
2
1.00
0.43
0
0.29
(Ras)(Rho_GDI)
1
C1
AB
7
7
7
9
7
9
52
1.00
1.00
0.86
0.86
(Ras)(RhoGAP)
1
C1
AB
5
5
5
6
5
6
23
1.00
1.00
1.00
1.00
(Ras)(RhoGEF)_(PH)
1
C1
AB
7
7
7
6
7
6
23
1.00
1.00
1.00
0.86
(HSP70)(peptide)
10
C2
A2B2
9
15
36
1
43
6
0
0.90
0.53
0.97
0.36
(HSP70)(peptide)
12
C2
A2B2
7
15
21
1
43
6
10
0.70
0
0
0.05
(HSP70)(peptide)
11
C2
A2B2
8
15
21
1
43
6
10
0.80
0.57
0
0
(Ras)(zf-RanBP)
1
C1
AB
6
6
17
3
17
3
24
1.00
0.94
0.53
0.71
(HSP70)(peptide)
49
D2
A4B4
8
15
21
1
43
6
10
0.80
0.57
0
0.76
(Ras)(RBD-FIP)
5
C2
A2B2
6
6
7
6
7
6
2
1.00
0.57
0.14
0.71
(RbpA)(RNA_pol_L[1-30])_(RNA_pol_A_bac)_(RNA_pol_L[31-73])_( RNA_pol_A_CTD)(RNA_pol_Rpb1_1)_(RNA_pol_Rpb1_2)_(RNA_pol_Rpb 1_3)_(RNA_pol_Rpb1_4)_(RNA_pol_Rpb1_5)(RNA_pol_Rpb2_1)_(RNA_ pol_Rpb2_2)_(RNA_pol_Rpb2_3)_(RNA_pol_Rpb2_45)_(RNA_pol_Rpb2 _6)_(RNA_pol_Rpb2_7)(RNA_pol_Rpb6)(Sigma70_r1_2)_(Sigma70_r2 )_(Sigma70_r3)_(Sigma70_r4)
1
unknown
AB2CDEF
5
5
5
7
5
7
5
1.00
1.00
0.40
1.00
(Response_reg)(peptide)
1
C1
AB
5
5
11
3
11
3
9
1.00
1.00
0.36
0.45
(RGM_N)(TGF_beta)
1
C1
AB
5
7
6
5
8
5
7
0.71
0.17
0
0.17
(RGM_N)(TGF_beta)
2
C1
AB
5
7
6
5
8
5
43
0.71
0.17
0
0.17
(RGM_N)(TGF_beta)
3
C2
A2B2
5
7
6
5
8
5
0
0.71
0.67
0
0.67
(RNA_pol_L[1-30])_(RNA_pol_A_bac)_(RNA_pol_L[31-74])_(RNA_po l_A_CTD)(RNA_pol_Rpb1_1)_(RNA_pol_Rpb1_1)_(RNA_pol_Rpb1_2)_( RNA_pol_Rpb1_3)_(RNA_pol_Rpb1_4)_(RNA_pol_Rpb1_5[9-66])_(RNA _pol_Rpb1_5)_(RNA_pol_Rpb1_5[67-266])(RNA_pol_Rpb2_1[2-155]) _(RNA_pol_Rpb2_2)_(RNA_pol_Rpb2_1[156-202])_(RNA_pol_Rpb2_3) _(RNA_pol_Rpb2_45)_(RNA_pol_Rpb2_6)_(RNA_pol_Rpb2_7)(RNA_pol _Rpb6)(Sigma70_r1_2)_(Sigma70_r2)_(Sigma70_r3)_(Sigma70_r4)
1
C1
A2BCDE
5
5
36
11
36
11
4
1.00
1.00
0
0.78
(RNA_pol_L[1-30])_(RNA_pol_A_bac)_(RNA_pol_L[31-74])_(RNA_po l_A_CTD)(RNA_pol_Rpb1_1)_(RNA_pol_Rpb1_2)_(RNA_pol_Rpb1_3)_( RNA_pol_Rpb1_4)_(RNA_pol_Rpb1_5)(RNA_pol_Rpb2_1[1-155])_(RNA _pol_Rpb2_2)_(RNA_pol_Rpb2_1[156-203])_(RNA_pol_Rpb2_2)_(RNA _pol_Rpb2_3)_(RNA_pol_Rpb2_45)_(RNA_pol_Rpb2_6)_(RNA_pol_Rpb 2_7)(RNA_pol_Rpb6)(UvrB_inter)_(CarD_CdnL_TRCF)_(DEAD)_(Heli case_C)_(TRCF)
1
unknown
A2BCDE
7
7
7
6
7
6
100
1.00
1.00
0.14
1.00
(RNA_pol_L[1-30])_(RNA_pol_A_bac)_(RNA_pol_L[31-74])_(RNA_po l_A_CTD)(RNA_pol_Rpb1_1)_(RNA_pol_Rpb1_2)_(RNA_pol_Rpb1_3)_( RNA_pol_Rpb1_4)_(RNA_pol_Rpb1_5)(RNA_pol_Rpb2_1[1-155])_(RNA _pol_Rpb2_2)_(RNA_pol_Rpb2_1[156-203])_(RNA_pol_Rpb2_3)_(RNA _pol_Rpb2_45)_(RNA_pol_Rpb2_6)_(RNA_pol_Rpb2_7)(RNA_pol_Rpb6 )(Sigma70_r1_1)_(Sigma70_r1_2)_(Sigma70_ner)_(Sigma70_r2)_(S igma70_r3)_(Sigma70_r4)
1
C1
A2BCDE
8
10
25
16
27
16
2
0.80
1.00
0.12
0.80
(RNA_pol_L[1-30])_(RNA_pol_A_bac)_(RNA_pol_L[31-74])_(RNA_po l_A_CTD)(RNA_pol_Rpb1_1)_(RNA_pol_Rpb1_2)_(RNA_pol_Rpb1_3)_( RNA_pol_Rpb1_4)_(RNA_pol_Rpb1_5)(RNA_pol_Rpb2_1[1-155])_(RNA _pol_Rpb2_2)_(RNA_pol_Rpb2_2)_(RNA_pol_Rpb2_1[156-203])_(RNA _pol_Rpb2_2)_(RNA_pol_Rpb2_3)_(RNA_pol_Rpb2_45)_(RNA_pol_Rpb 2_6)_(RNA_pol_Rpb2_7)(RNA_pol_Rpb6)(Sigma70_r1_1)_(Sigma70_r 1_2)_(Sigma70_ner)_(Sigma70_r2)_(Sigma70_r3)_(Sigma70_r4)(zf -dskA_traR)
1
unknown
A3BCDEF
5
7
5
9
7
9
3
0.71
1.00
0.40
1.00
(RRM_1)(peptide)
1
C1
AB
5
14
5
3
17
7
0
1.00
0.80
0
0.80
(RuBisCO_large_N)_(RuBisCO_large)(RuBisCO_small)
12
C2
A2B2
5
23
10
14
62
48
11
1.00
0
0
0
(RuBisCO_large_N)_(RuBisCO_large)(RuBisCO_small)
13
C2
A2B2
5
23
10
14
62
48
11
1.00
0
0
0
(RuBisCO_large_N)_(RuBisCO_large)(RuBisCO_small)
14
C2
A2B2
5
23
10
14
62
48
11
1.00
0
0
0
(RuBisCO_large_N)_(RuBisCO_large)(RuBisCO_small)
15
C2
A2B2
5
23
10
14
62
48
11
1.00
0
0
0
(SAUGI)(UDG)
1
C1
AB
5
6
5
6
6
7
37
1.00
1.00
1.00
0.80
(Serpin)(Thrombin_light)(Trypsin)
1
C1
ABC
5
6
5
5
6
5
3
1.00
1.00
0.80
0.80
(SET)(peptide)
1
C1
AB
11
11
38
6
38
6
0
1.00
0.95
0.87
0.92
(SET)_(Rubis-subs-bind)(peptide)
1
C1
AB
5
5
19
2
20
2
23
1.00
1.00
0.95
0.89
(SH2)_(SH2)(peptide)
1
C1
AB
6
8
6
2
8
3
0
1.00
1.00
1.00
1.00
(SH3_1)(Trypsin)
1
C1
AB
6
6
6
1
6
1
94
1.00
1.00
0.17
0.67
(SH3_1)(Trypsin)
2
C1
AB
5
6
5
1
6
1
94
0.83
0
0
0
(SIR2)(peptide)
1
C1
AB
40
44
89
12
94
13
0
1.00
0.97
0.44
0.71
(Sina)(peptide)
1
C1
AB
5
5
7
2
7
2
18
1.00
0.71
0.57
0.71
(Sina)(peptide)
3
C2
A2B2
5
5
7
2
7
2
18
1.00
0.29
0.43
0.29
(Spin-Ssty)_(Spin-Ssty)_(Spin-Ssty)(peptide)
1
C1
AB
5
8
9
3
12
3
0
1.00
0.89
0.44
0.44
(SPRY)(peptide)
1
C1
AB
8
11
9
4
12
6
52
1.00
1.00
0.67
0.56
(Squash)(Trypsin)
1
C1
AB
9
9
11
11
11
11
1
1.00
1.00
1.00
0.91
(STPPase_N)_(Metallophos)(peptide)
1
C1
AB
8
16
9
4
23
6
0
0.72
1.00
0.89
0.78
(T6SS_VipA)(VipB)_(VipB_2)
1
C1
AB
5
5
5
8
5
8
14
1.00
0
0.80
0.60
(Kazal_1)(Trypsin)
1
C1
AB
11
11
36
16
36
16
13
1.00
1.00
0.83
1.00
(Thioredoxin)(peptide)
1
C1
AB
5
5
8
4
8
4
21
1.00
0.75
0.75
0.75
(Kunitz_BPTI)(Trypsin)
1
C1
AB
33
37
87
26
92
29
1
0.94
0.97
1.00
0.54
(TNF)(TNFR_c6)_(TNFR_c6)
1
C1
AB
6
6
6
7
6
7
19
1.00
0
0
0
(TNF)(TNFR_c6)_(TNFR_c6)
2
C1
AB
5
6
5
5
6
7
20
1.00
0
0
0
(TNF)(TNFR_c6)_(TNFR_c6)_(TNFR_c6)_(TNFR_c6)
1
C1
AB
7
8
10
10
11
12
21
1.00
0
0
0
(TNF)(TNFR_c6)_(TNFR_c6)_(TNFR_c6)_(TNFR_c6)
2
C1
AB
7
8
10
10
11
12
21
1.00
0
0
0
(TNF)(TNFR_c6)_(TNFR_c6)_(TNFR_c6)_(TNFR_c6)
12
C3
A3B3
7
8
10
10
11
12
2
1.00
0.90
0.10
0.40
(TNF)(TNFR_c6)_(TNFR_c6)
3
C3
A3B3
5
6
5
5
6
7
3
1.00
1.00
0.80
0.80
(Toxin_R_bind_N)_(Toxin_R_bind_C)(peptide)
1
C1
AB
5
7
5
2
7
3
16
1.00
1.00
0
1.00
(TPR_11)_(TPR_1)(peptide)
1
C1
AB
5
5
5
3
5
3
20
1.00
0.80
0.80
0.80
(TPR_11)_(TPR_11)_(TPR_11)_(TPR_11)_(Glyco_transf_41)(peptid e)
1
C1
AB
6
6
29
1
29
1
12
1.00
0.93
0.31
0.07
(TRF)(peptide)
1
C1
AB
9
10
9
2
10
2
0
0.90
0.67
0
0
(TRF)(peptide)
3
C2
A2B2
9
10
9
2
10
2
0
0.90
0.67
0.78
0.89
(Trypsin_2)_(PDZ_2)(peptide)
1
C1
AB
8
11
15
3
19
6
34
1.00
0.07
0
0
(Trypsin_2)_(PDZ_2)(peptide)
7
C3
A3B3
5
11
7
2
19
6
46
0.71
0.86
0.43
0.43
(ubiquitin)(UQ_con)_(UBA)
1
C1
AB
5
7
6
3
8
3
97
1.00
0.50
0
0.33
(UEV)(peptide)
1
C1
AB
6
7
10
1
11
2
89
1.00
1.00
0.80
1.00
(USP7_ICP0_bdg)_(USP7_C2)(peptide)
1
C1
AB
5
6
7
1
8
1
40
1.00
0.86
0.29
0.43
(Vac_ImportDeg)(peptide)
1
C1
AB
8
8
11
2
11
2
34
1.00
1.00
0.82
0.82
(VHS)(peptide)
1
C1
AB
6
6
11
2
11
2
22
1.00
0.91
0.36
0.55
(VHS)(peptide)
2
C2
A2B2
6
6
11
2
11
2
22
1.00
0.18
0.09
0
(V-set)(V-set_CD47)
1
C1
AB
5
5
5
2
5
2
79
1.00
1.00
1.00
0.80
(V-set)_(C1-set)(V-set)_(C1-set)_(C1-set)_(C1-set)
1
C1
AB
7
11
7
7
11
9
28
1.00
0.29
0.29
0.43
(V-set)_(C1-set)(V-set)_(C1-set)_(C1-set)_(C1-set)
2
C2
A2B2
5
11
5
5
11
9
24
1.00
0.80
0.80
1.00
(MCR_alpha_N)_(MCR_alpha)(MCR_beta_N)_(MCR_beta)(MCR_gamma)
1
C1
ABC
10
10
27
27
27
27
3
1.00
0
0
0.04
(MCR_alpha_N)_(MCR_alpha)(MCR_beta_N)_(MCR_beta)(MCR_gamma)
2
C1
ABC
9
10
26
24
27
27
3
1.00
0
0
0.04
(MCR_alpha_N)_(MCR_alpha)(MCR_beta_N)_(MCR_beta)(MCR_gamma)
3
C1
ABC
9
10
26
24
27
27
9
1.00
0
0
0.04
(MCR_alpha_N)_(MCR_alpha)(MCR_beta_N)_(MCR_beta)(MCR_gamma)
4
C1
ABC
9
10
26
24
27
27
9
1.00
0
0
0.04
(WW)_(WW)(peptide)
1
C1
AB
8
9
8
3
9
4
7
1.00
1.00
0
0.25
(MHC_I)(V-set)_(C1-set)(V-set)_(DUF1968)(peptide)
1
C1
ABCD
6
6
10
3
10
3
0
1.00
1.00
0
0.10
(AP_endonuc_2)(DUF6379)
1
C1
AB
5
5
8
6
9
6
11
1.00
0.25
0.63
0.50
(E3_binding)(Pyr_redox_2)_(Pyr_redox_dim)
1
C1
AB2
6
6
6
10
6
10
9
1.00
1.00
0
0.17
(MHC_II_alpha)_(C1-set)(MHC_II_beta)_(C1-set)
1
C1
AB
30
31
37
36
38
39
9
1.00
0.95
0.92
0.73
(AlaDh_PNT_N)_(AlaDh_PNT_C)(PNTB)
1
C1
A2B
6
6
14
5
14
5
4
1.00
1.00
0
1.00
(ATP-synt)(ATP-synt_ab_N)_(ATP-synt_ab)_(ATP-synt_ab_C)(ATP- synt_ab_N)_(ATP-synt_ab)_(T3SS_ATPase_C)(ATP-synt_DE_N)_(ATP -synt_DE)
1
C1
AB3C3D
5
5
6
20
6
20
3
1.00
1.00
0
0.83
(MHC_II_alpha)_(C1-set)(MHC_II_beta)_(C1-set)(Stap_Strp_toxi n)_(Stap_Strp_tox_C)(peptide)
1
C1
ABCD
8
10
17
7
19
10
0
0.80
0.88
0
0
(ABC_tran)_(BCA_ABC_TP_C)(LptF_LptG)
1
C1
A2B2
7
7
7
12
7
12
4
1.00
1.00
0
1.00
(ATP-synt)(ATP-synt_A)(ATP-synt_ab_N)_(ATP-synt_ab)_(ATP-syn t_ab_C)(ATP-synt_ab_N)_(ATP-synt_ab)_(T3SS_ATPase_C)(ATP-syn t_B)(ATP-synt_C)(ATP-synt_DE_N)_(ATP-synt_DE)(OSCP)
1
C1
ABC3D3E2F10GH
12
27
12
13
27
23
1
0.85
1.00
0
1.00
(ATP-synt)(ATP-synt_A)(ATP-synt_ab_N)_(ATP-synt_ab)_(ATP-syn t_ab_C)(ATP-synt_ab_N)_(ATP-synt_ab)_(T3SS_ATPase_C)(ATP-syn t_B)(ATP-synt_C)(ATP-synt_DE_N)_(ATP-synt_DE)(OSCP)
3
C1
ABC3D3E2F14GH
12
27
12
10
27
23
100
1.00
1.00
0
1.00
(ABC_tran)(MlaD)(MlaE)(STAS_2)
1
C2
A2B6C2D2
11
12
11
12
12
14
4
1.00
1.00
0
1.00
(Cas_Cmr3)_(Csm4_C)(Csm2_III-A)(HD)_(Csm1_B)_(Csm1_B)(RAMPs)
1
C1
AB2CD4
7
7
7
5
7
5
100
1.00
1.00
0
1.00
(ATP-synt)(ATP-synt_ab_N)_(ATP-synt_ab)_(ATP-synt_ab_C)(ATP- synt_ab_N)_(ATP-synt_ab)_(T3SS_ATPase_C)(ATP-synt_C)(ATP-syn t_DE_N)(ATP-synt_Eps)(OSCP)
1
C1
AB3C3D10EFG
16
16
16
7
16
7
100
1.00
1.00
0
1.00
(ATP-synt)(ATP-synt_ab_N)_(ATP-synt_ab)_(ATP-synt_ab_C)(ATP- synt_ab_N)_(ATP-synt_ab)_(T3SS_ATPase_C)(ATP-synt_DE_N)_(ATP -synt_DE)(OSCP)
1
C1
AB3C3DE
6
6
6
5
6
5
100
1.00
1.00
0
1.00
(MotA_ExbB)(MotB_plug)_(OmpA)
1
C1
A5B2
5
5
5
5
5
5
24
1.00
1.00
0
1.00
(Aha1_N)_(AHSA1)(HATPase_c)_(HSP90)
1
C1
AB
5
5
5
2
5
2
100
1.00
0
0
1.00
(Collagen)(DUF5095)(MSP1_C)(MSP1_C)_(EGF_MSP1_1)_(EGF_3)
1
C1
ABCD
6
6
6
3
6
3
100
1.00
1.00
1.00
1.00
(ArenaCapSnatch)_(Arena_RNA_pol)(zf-P11)
1
C1
AB
7
7
7
6
7
6
13
1.00
0.71
0.14
1.00
(bCoV_S1_N)_(bCoV_S1_RBD)_(CoV_S1_C)_(CoV_S2)(Peptidase_M2)_ (GFP)
1
C1
AB
11
11
11
2
11
2
97
1.00
0.36
0
1.00
(B3R)_(AlbA_2)(PDEase_I)
1
C1
AB
5
5
5
2
5
2
99
1.00
0
0
1.00
(2Fe-2S_thioredx)(Complex1_30kDa)_(Complex1_49kDa)(Complex1_ 51K)_(SLBB)_(NADH_4Fe-4S)(Fer2_4)_(NADH-G_4Fe-4S_3)_(Molybdo p_Fe4S4)_(Molybdopterin)(Fer4_7)(NADHdh)(Oxidored_q2)(Oxidor ed_q3)(Oxidored_q4)(Oxidored_q5_N)_(Proton_antipo_M)(Oxidore d_q6)(Proton_antipo_M)(Proton_antipo_N)_(Proton_antipo_M)_(N ADH5_C)
1
C1
ABCDEFGHIJKLM
6
8
6
35
8
35
4
1.00
1.00
1.00
1.00
(Actin)(EF-hand_7)(Myosin_N)_(Myosin_head)_(IQ)(peptide)
1
C1
ABCD
18
18
18
3
18
3
100
1.00
1.00
0
1.00
(ABC_tran)_(ABC2_membrane)(V-set)_(C1-set)
1
C1
A2B2
5
6
5
2
6
2
100
1.00
1.00
0
1.00
(EGF)(Recep_L_domain)_(Furin-like)_(Recep_L_domain)_(GF_rece p_IV)_(PK_Tyr_Ser-Thr)
1
C1
AB
6
6
6
3
6
3
42
1.00
0
0
1.00
(EGF)(Recep_L_domain)_(Furin-like)_(Recep_L_domain)_(GF_rece p_IV)_(PK_Tyr_Ser-Thr)
2
C2
A2B2
6
6
6
3
6
3
42
1.00
1.00
1.00
1.00
(Ion_trans)_(cNMP_binding)(Ion_trans)_(cNMP_binding)_(CLZ)
1
C1
AB3
9
9
9
6
9
6
27
1.00
1.00
0
1.00
(NHase_alpha)(NHase_beta)
1
C1
AB
8
9
58
9
65
12
7
1.00
0.76
0.62
0.31
(NHase_alpha)(NHase_beta)
2
C1
AB
8
9
53
9
65
12
12
1.00
0
0
0
(NiFeSe_Hases)(Oxidored_q6)_(NiFe_hyd_SSU_C)
1
C1
AB
24
24
117
38
117
38
6
1.00
0.72
0.80
0.68
(NiFeSe_Hases)(Oxidored_q6)_(NiFe_hyd_SSU_C)
2
C1
AB
7
24
38
21
117
38
12
0.87
0
0
0.03
(OTCace_N)_(OTCace)(PyrI)_(PyrI_C)
1
C1
AB
7
7
65
8
65
8
10
1.00
0
0
0
(OTCace_N)_(OTCace)(PyrI)_(PyrI_C)
8
C2
A2B2
6
7
64
8
65
8
10
0.85
0
0
0
(OTCace_N)_(OTCace)(PyrI)_(PyrI_C)
35
C3
A3B3
7
7
65
8
65
8
10
1.00
0
0.08
0
(PALP)(Trp_syntA)
5
C2
A2B2
8
9
136
13
141
15
9
1.00
0.76
1.00
0.66
(PCNA_N)_(PCNA_C)(peptide)
1
C1
AB
28
35
34
8
42
9
0
0.87
0.09
0.12
0.18
(Peptidase_C1)(peptide)
1
C1
AB
10
16
12
8
33
12
35
0.90
1.00
0.58
0.83
(Peptidase_C30)(peptide)
1
C1
AB
31
35
69
12
78
15
10
0.96
0.10
0
0.04
(Peptidase_C30)(peptide)
3
C2
A2B2
25
35
63
12
78
15
10
0.78
0.86
0.24
0.73
(Peptidase_C48)(Rad60-SLD)
1
C1
AB
10
11
12
9
13
10
17
1.00
1.00
0.92
0.83
(Peptidase_M1_N)_(Peptidase_M1)_(ERAP1_C)(peptide)
1
C1
AB
9
11
12
6
15
8
28
1.00
0.83
0.42
0.58
(PHD)(peptide)
1
C1
AB
28
35
49
30
59
35
0
1.00
0.80
0.24
0.67
(Phe_tRNA-synt_N)_(tRNA-synt_2d)(tRNA_bind)_(B3_4)_(B5)_(tRN A_synthFbeta)_(FDX-ACB)
1
C1
AB
9
9
27
16
27
16
11
1.00
0
0
0.07
(Phe_tRNA-synt_N)_(tRNA-synt_2d)(tRNA_bind)_(B3_4)_(B5)_(tRN A_synthFbeta)_(FDX-ACB)
2
C1
AB
9
9
27
16
27
16
11
1.00
0
0.22
0.04
(POLO_box)_(POLO_box)(peptide)
1
C1
AB
21
24
40
3
43
3
13
0.91
1.00
0.45
0.98
(Polyketide_cyc2)(PP2C)
1
C1
AB
16
16
37
15
44
15
6
1.00
1.00
0.89
0.81
(PPTA)_(PPTA)_(PPTA)_(PPTA)_(PPTA)(Prenyltrans)_(Prenyltrans )_(Prenyltrans)_(Prenyltrans)_(Prenyltrans)
1
C1
AB
5
5
63
6
63
6
19
1.00
1.00
1.00
1.00
(Proteasome)(Proteasome)_(Pr_beta_C)(Proteasome_A_N)_(Protea some)
2
C1
A6BC7
27
28
241
142
242
142
5
0.96
0
0.93
0.07
(C1-set)(MHC_I)_(C1-set)(Ras)
1
C1
ABC
5
6
12
8
13
8
0
1.00
1.00
0
0.92
(Ricin_B_lectin)_(Ricin_B_lectin)(RIP)
1
C1
AB
12
12
39
10
39
10
10
1.00
0.97
0.49
0.77
(Rieske)_(Ring_hydroxyl_A)(Ring_hydroxyl_B)
1
C1
AB
16
18
52
26
54
28
12
1.00
0
0
0
(Rieske)_(Ring_hydroxyl_A)(Ring_hydroxyl_B)
2
C1
AB
16
18
52
26
54
28
12
1.00
0
0
0
(RNA_pol_L[1-30])_(RNA_pol_A_bac)_(RNA_pol_L[31-74])_(RNA_po l_A_CTD)(RNA_pol_Rpb1_1)_(RNA_pol_Rpb1_2)_(RNA_pol_Rpb1_3)_( RNA_pol_Rpb1_4)_(RNA_pol_Rpb1_5)(RNA_pol_Rpb2_1[1-155])_(RNA _pol_Rpb2_2)_(RNA_pol_Rpb2_1[156-203])_(RNA_pol_Rpb2_3)_(RNA _pol_Rpb2_45)_(RNA_pol_Rpb2_6)_(RNA_pol_Rpb2_7)(RNA_pol_Rpb6 )
1
C1
A2BCD
9
15
9
5
15
5
100
1.00
1.00
0
1.00
(Hirudin)(Thrombin_light)(Trypsin)
1
C1
ABC
14
17
257
12
264
12
0
0.82
1.00
0.73
0.37
(RuBisCO_large_N)_(RuBisCO_large)(RuBisCO_small)
40
C4
A4B4
16
23
55
37
62
48
4
0.93
0
0
0.11
(RuBisCO_large_N)_(RuBisCO_large)(RuBisCO_small)
41
C4
A4B4
16
23
55
37
62
48
4
0.93
0
0
0.09
(RuBisCO_large_N)_(RuBisCO_large)(RuBisCO_small)
42
D2
A4B4
5
23
10
14
62
48
11
1.00
0
0
0
(RuBisCO_large_N)_(RuBisCO_large)(RuBisCO_small)
43
D2
A4B4
5
23
10
14
62
48
11
1.00
0
0
0
(RuBisCO_large_N)_(RuBisCO_large)(RuBisCO_small)
55
D4
A8B8
17
23
56
39
62
48
0
0.93
1.00
0.70
0.52
(RVP)(peptide)
2
C1
A2B
21
28
77
20
95
22
0
0.80
1.00
0
0.90
(SBP_bac_5)(peptide)
1
C1
AB
19
22
59
14
63
17
14
1.00
1.00
0.81
0.97
(Serpin)(peptide)
1
C1
AB
37
48
61
19
75
24
7
1.00
0.97
0.98
0.89
(SNF)(V-set)
1
C1
AB2
9
13
9
1
13
3
26
1.00
1.00
0.22
1.00
(Hormone_recep)(SRC-1)
1
C1
AB
59
76
404
33
445
34
0
0.78
0.37
0.25
0.37
(TBP)_(TBP)(TFIIB)_(TFIIB)
1
C1
AB
5
5
7
6
7
6
18
1.00
1.00
0.71
0.71
(Thrombin_light)(Trypsin)
1
C1
AB
38
40
85
3
89
4
3
0.97
0.98
0.68
0.78
(UDG)(UDI)
1
C1
AB
10
11
12
8
13
10
9
1.00
0.92
1.00
0.75
(Vinculin)(peptide)
1
C1
AB
20
25
20
4
25
5
0
0.95
1.00
0.90
0.70
(V-set)_(C1-set)(V-set_2)_(C1-set)(peptide)
1
C1
ABC
36
40
46
2
50
2
0
1.00
1.00
0.07
0.72
(V-set)_(C1-set)(V-set_2)_(C1-set)(peptide)
4
C1
ABC
5
40
5
2
50
2
0
1.00
0.60
0
0.20
(WD40)_(WD40)_(WD40)_(WD40)_(WD40)_(WD40)_(WD40)(peptide)
1
C1
AB
16
30
35
1
61
5
55
0.72
0.97
0.94
1.00
(YBD)(peptide)
1
C1
AB
11
13
21
3
23
4
0
1.00
0.95
0.90
0.52
(YBD)(peptide)
6
C2
A2B2
9
13
19
3
23
4
23
0.81
0.05
0
0.16
(YEATS)(peptide)
1
C1
AB
16
21
24
5
32
8
10
1.00
0.79
0.25
0.50
(YEATS)(peptide)
5
C2
A2B2
10
21
12
2
32
8
10
0.90
0
0
0.33
(RVT_1)_(RVT_thumb)_(RVT_connect)(RVT_1)_(RVT_thumb)_(RVT_co nnect)_(RNase_H)
1
C1
AB
42
42
330
12
346
12
11
1.00
1.00
0.86
0.85
(V-set)_(C1-set)(peptide)
21
C1
A2B
9
263
24
2
546
42
0
1.00
0
0
0.04
(V-set)_(C1-set)(peptide)
26
C1
A2B
8
263
23
2
546
42
0
1.00
0
0
0.13
(V-set)_(C1-set)(peptide)
17
C1
A2B
10
263
14
1
546
42
0
1.00
0
0
0
(V-set)_(C1-set)(peptide)
47
C1
A2B
6
263
8
2
546
42
0
1.00
0
0
0.13
(V-set)_(C1-set)(peptide)
39
C1
A2B
7
263
8
2
546
42
0
1.00
0
0
0
(V-set)_(C1-set)(peptide)
40
C1
A2B
7
263
7
2
546
42
11
1.00
0
0
0
(V-set)_(C1-set)(peptide)
54
C1
A2B
6
263
7
1
546
42
0
1.00
0
0
0.29
(V-set)_(C1-set)(peptide)
85
C1
A2B
5
263
5
1
546
42
0
1.00
0.60
0
0.40
(V-set)(peptide)
11
C1
A2B
9
40
13
5
51
15
0
1.00
0.92
0.08
0.69
(Arena_glycoprot)(C1-set)(MHC_I)_(C1-set)
12
C2
A2B2C2
6
7
18
8
20
8
0
0.85
0
0
0
(bCoV_S1_N)_(bCoV_S1_RBD)_(CoV_S1_C)(Peptidase_M2)
1
C1
AB
17
17
25
7
26
8
3
1.00
1.00
0
1.00
(bCoV_S1_N)_(bCoV_S1_RBD)_(CoV_S1_C)_(CoV_S2)(Peptidase_M2)
1
C1
AB
33
52
33
3
52
5
12
0.75
0.67
0
0.97
(C1-set)(CoV_S2)(MHC_I)_(C1-set)
1
C1
ABC
6
7
8
10
10
10
0
1.00
1.00
0
1.00
(C1-set)(Flu_M1)(MHC_I)_(C1-set)
1
C1
ABC
6
7
9
8
10
10
0
1.00
1.00
0
1.00
(C1-set)(MHC_I)_(C1-set)(MLANA)(V-set)_(C1-set)(V-set)_(DUF1 968)
1
C1
ABCDE
7
8
15
7
16
8
0
1.00
1.00
0.33
0.73
(CBFB_NFYA)(CBFD_NFYB_HMF)
1
C1
AB2
6
6
9
14
9
14
0
1.00
0.78
0.67
0.67
(CENP-S)(CENP-X)
5
C2
A2B2
9
9
10
6
10
6
8
1.00
1.00
0.20
0.60
(Como_LCP)(Como_SCP)
1
C3
AB
7
7
9
2
9
2
14
1.00
1.00
0.44
0.78
(Cytochrom_B562)_(7tm_1)(G-alpha)(G-gamma)(V-set)_(V-set)(Za pB)_(WD40)_(WD40)_(WD40)_(WD40)_(WD40)_(WD40)
1
C1
ABCDE
7
10
7
9
10
11
4
1.00
1.00
0
1.00
(Cytochrom_C1)(Cytochrome_B)_(Cytochrom_B_C)(UCR_Fe-S_N)_(Ri eske)
1
C2-C2
ABC
7
8
14
15
15
18
4
1.00
0
0
0.29
(Cytochrom_C1)(Cytochrome_B)_(Cytochrom_B_C)(UCR_Fe-S_N)_(Ri eske)
2
C1-C2
ABC
7
8
14
15
15
18
4
1.00
0
0.14
0.29
(Cytochrom_C1)(Cytochrome_B)_(Cytochrom_B_C)(UCR_Fe-S_N)_(Ri eske)
3
C1-C2
ABC
7
8
14
15
15
18
6
1.00
0
0
0.29
(Cytochrom_C1)(Cytochrome_B)_(Cytochrom_B_C)(Peptidase_M16)_ (Peptidase_M16_C)(Ubiq-Cytc-red_N)(UCR_14kD)(UCR_6-4kD)(UCR_ hinge)(UCR_TM)_(Rieske)(UCR_UQCRX_QCR9)(UcrQ)
4
C2
A2B2C4D2E2F2G2H2I2J2
5
6
17
20
20
20
0
1.00
1.00
0.41
1.00
(Cytochrom_C1)(Cytochrome_B)_(Cytochrom_B_C)(UCR_Fe-S_N)_(Ri eske)
8
C1-C1-C2
A2B2C2
7
8
14
15
15
18
2
1.00
1.00
0.64
1.00
(Cytochrom_B562)_(7tm_1)(G-alpha)(G-gamma)(V-set)_(V-set)(WD 40)_(WD40)_(WD40)_(WD40)_(WD40)_(WD40)
1
C1
ABCDE
8
10
8
12
10
13
0
1.00
1.00
0
1.00
(DNA_RNApol_7kD)(RNA_pol_A_bac)(RNA_pol_I_A49)(RNA_pol_L_2)( RNA_POL_M_15KD)_(TFIIS_C)(RNA_pol_N)(RNA_pol_Rpb1_1)_(RNA_po l_Rpb1_2)_(RNA_pol_Rpb1_3)_(RNA_pol_Rpb1_4)_(RNA_pol_Rpb1_5) (RNA_pol_Rpb2_1[2-155])_(RNA_pol_Rpb2_2)_(RNA_pol_Rpb2_1[156 -201])_(RNA_pol_Rpb2_3)_(RNA_pol_Rpa2_4)_(RNA_pol_Rpb2_6)_(R NA_pol_Rpb2_7)(RNA_pol_Rpb5_N)_(RNA_pol_Rpb5_C)(RNA_pol_Rpb6 )(RNA_pol_Rpb8)(RNA_polI_A14)(RNA_polI_A34)(SHS2_Rpb7-N)_(RP A43_OB)
1
C1
ABCDEFGHIJKLMN
8
8
10
14
12
14
2
1.00
1.00
0.70
0.70
(DNA_topoisoIV)(Toprim)_(DNA_gyraseB_C)
6
C2
A2B2
11
11
39
9
39
9
5
1.00
1.00
0.54
0.97
(DOT1)(Histone)(Histone)_(Histone_H2A_C)(TAF)(ubiquitin)
1
unknown
AB4C2D2E
6
10
6
12
10
17
4
0.75
1.00
0
1.00
(FGF)(I-set)_(I-set)
1
C1
AB
9
9
10
6
10
6
31
1.00
0.60
1.00
0.70
(GP120)(V-set)_(C1-set)(V-set_2)_(C1-set)
1
C1
ABC
27
47
43
13
64
27
1
0.96
1.00
0.26
0.58
(GP120)(V-set)_(C1-set)(V-set_2)_(C1-set)
2
C1
ABC
18
47
34
9
64
27
7
0.81
0
0
0
(GP120)(V-set)_(C1-set)(V-set_2)_(C1-set)
3
C1
ABC
18
47
34
9
64
27
4
0.81
0
0
0
(GP120)(V-set)_(C1-set)(V-set_2)_(C1-set)
4
C1
ABC
13
47
14
10
64
27
0
1.00
1.00
0.07
0.64
(Hormone_recep)(peptide)
1
C1
AB
174
217
751
43
850
50
8
0.83
0.64
0.40
0.47
(IBN_N)_(Xpo1)_(CRM1_repeat)_(CRM1_repeat_2)_(CRM1_repeat_3) _(CRM1_C)(Ran_BP1)(Ras)(peptide)
33
C2
A2B2C2D2
6
8
21
3
31
3
0
0.75
0
0
0
(IBN_N)_(Xpo1)_(CRM1_repeat)_(CRM1_repeat_2)_(CRM1_repeat_3) _(CRM1_C)(Ran_BP1)(Ras)(peptide)
34
C2
A2B2C2D2
6
8
21
3
31
3
0
0.75
0
0
0
(IBN_N)_(Xpo1)_(CRM1_repeat)_(CRM1_repeat_2)_(CRM1_repeat_3) _(CRM1_C)(Ran_BP1)(Ras)(peptide)
35
C2
A2B2C2D2
6
8
18
3
31
3
0
0.75
0
0
0.11
(IBN_N)_(Xpo1)_(CRM1_repeat)_(CRM1_repeat_2)_(CRM1_repeat_3) _(CRM1_C)(Ran_BP1)(Ras)(peptide)
36
C2
A2B2C2D2
6
8
18
3
31
3
0
0.75
0
0
0
(Ion_trans)_(Na_trans_cytopl)_(Ion_trans)_(Na_trans_assoc)_( Ion_trans)_(Ion_trans)_(GPHH)(V-set)
1
C1
AB2
11
18
11
3
18
5
99
1.00
1.00
0
1.00
(Ion_trans_2)(V-set)_(C1-set)
32
C4
A4B8
6
8
67
4
84
5
0
0.75
0.90
0.01
0.25
(KH_2)_(Ribosomal_S3_C)(KOW)_(Ribosomal_L14e)(KOW)_(Ribosoma l_L27e)(Ribosom_S12_S23)(Ribosomal_L13)(Ribosomal_L13e)(Ribo somal_L14)(Ribosomal_L15e)(Ribosomal_L16)(Ribosomal_L18)(Rib osomal_L18A)(Ribosomal_L19e)(Ribosomal_L2)_(Ribosomal_L2_C)( Ribosomal_L21e)(Ribosomal_L22)(Ribosomal_L22e)(Ribosomal_L23 eN)_(Ribosomal_L23)(Ribosomal_L24e)(Ribosomal_L26[1-43])_(KO W)_(Ribosomal_L26[44-82])(Ribosomal_L27A)(Ribosomal_L29)(Rib osomal_L29e)(Ribosomal_L3)(Ribosomal_L30_N)_(Ribosomal_L30)( Ribosomal_L31e)(Ribosomal_L32e)(Ribosomal_L34e)(Ribosomal_L3 5Ae)(Ribosomal_L36e)(Ribosomal_L37ae)(Ribosomal_L37e)(Riboso mal_L38e)(Ribosomal_L39)(Ribosomal_L4)_(Ribos_L4_asso_C)(Rib osomal_L40e)(Ribosomal_L41)(Ribosomal_L44)(Ribosomal_L5)_(Ri bosomal_L5_C)(Ribosomal_L5e)_(Ribosomal_L18_c)(Ribosomal_L6) _(Ribosomal_L6)(Ribosomal_L6e)(Ribosomal_L7Ae)(Ribosomal_S10 )(Ribosomal_S11)(Ribosomal_S13)(Ribosomal_S13_N)_(Ribosomal_ S15)(Ribosomal_S14)(Ribosomal_S17_N)_(Ribosomal_S17)(Ribosom al_S17e)(Ribosomal_S19)(Ribosomal_S19e)(Ribosomal_S2)(Riboso mal_S21e)(Ribosomal_S24e)(Ribosomal_S25)(Ribosomal_S26e)(Rib osomal_S27)(Ribosomal_S27e)(Ribosomal_S28e)(Ribosomal_S30)(R ibosomal_S3Ae)(Ribosomal_S5)_(Ribosomal_S5_C)(Ribosomal_S6e) (Ribosomal_S7)(Ribosomal_S7e)(Ribosomal_S8)(Ribosomal_S8e)(R ibosomal_S9)(RS4NT)_(S4)_(Ribosomal_S4e)_(KOW)_(40S_S4_C)(S1 0_plectin)(S4)(Stm1_N)_(HABP4_PAI-RBP1)(WD40)_(WD40)_(WD40)_ (WD40)_(WD40)_(WD40)_(WD40)
1
C1
ABCDEFGHIJKLMNOPQRSTUVWXYZabcdefghijklmnop3qrstuvwxyz0123456789(AA)(AB)(AC)(AD)(AE)(AF)(AG)(AH)(AI)(AJ)(AK)
9
9
12
80
12
80
13
1.00
1.00
0.08
1.00
(KH_2)_(Ribosomal_S3_C)(KOW)_(Ribosomal_L14e)(KOW)_(Ribosoma l_L27e)(Ribosom_S12_S23)(Ribosomal_L13)(Ribosomal_L13e)(Ribo somal_L14)(Ribosomal_L15e)(Ribosomal_L16)(Ribosomal_L18)(Rib osomal_L18A)(Ribosomal_L19e)(Ribosomal_L2)_(Ribosomal_L2_C)( Ribosomal_L21e)(Ribosomal_L22)(Ribosomal_L22e)(Ribosomal_L23 eN)_(Ribosomal_L23)(Ribosomal_L24e)(Ribosomal_L26[1-43])_(KO W)_(Ribosomal_L26[44-82])(Ribosomal_L27A)(Ribosomal_L29)(Rib osomal_L29e)(Ribosomal_L3)(Ribosomal_L30_N)_(Ribosomal_L30)( Ribosomal_L31e)(Ribosomal_L32e)(Ribosomal_L34e)(Ribosomal_L3 5Ae)(Ribosomal_L36e)(Ribosomal_L37ae)(Ribosomal_L37e)(Riboso mal_L38e)(Ribosomal_L4)_(Ribos_L4_asso_C)(Ribosomal_L40e)(Ri bosomal_L44)(Ribosomal_L5)_(Ribosomal_L5_C)(Ribosomal_L5e)_( Ribosomal_L18_c)(Ribosomal_L6)_(Ribosomal_L6)(Ribosomal_L6e) (Ribosomal_L7Ae)(Ribosomal_S10)(Ribosomal_S11)(Ribosomal_S13 )(Ribosomal_S13_N)_(Ribosomal_S15)(Ribosomal_S14)(Ribosomal_ S17_N)_(Ribosomal_S17)(Ribosomal_S17e)(Ribosomal_S19)(Riboso mal_S19e)(Ribosomal_S2)(Ribosomal_S21e)(Ribosomal_S24e)(Ribo somal_S25)(Ribosomal_S26e)(Ribosomal_S27)(Ribosomal_S27e)(Ri bosomal_S28e)(Ribosomal_S30)(Ribosomal_S3Ae)(Ribosomal_S5)_( Ribosomal_S5_C)(Ribosomal_S6e)(Ribosomal_S7)(Ribosomal_S7e)( Ribosomal_S8)(Ribosomal_S8e)(Ribosomal_S9)(RS4NT)_(S4)_(Ribo somal_S4e)_(KOW)_(40S_S4_C)(S10_plectin)(S4)(Stm1_N)_(HABP4_ PAI-RBP1)(WD40)_(WD40)_(WD40)_(WD40)_(WD40)_(WD40)_(WD40)(pe ptide)
1
C1
ABCDEFGHIJKLMNOPQRSTUVWXYZabcdefghijklmn3opqrstuvwxyz0123456789(AA)(AB)(AC)(AD)(AE)(AF)(AG)(AH)(AI)(AJ)2
9
9
12
78
12
78
13
1.00
1.00
0.08
1.00
(MCR_alpha_N)_(MCR_alpha)(MCR_beta_N)_(MCR_beta)(MCR_gamma)
5
C2
A2B2C2
10
10
27
27
27
27
3
1.00
1.00
1.00
0.96
(MHC_II_alpha)_(C1-set)(MHC_II_beta)_(C1-set)(Tryp_alpha_amy l)(V-set)_(C1-set)(V-set)_(DUF1968)
1
C1
ABCDE
5
5
5
11
5
11
6
1.00
1.00
0.20
0
(NHase_alpha)(NHase_beta)
21
C2
A2B2
7
9
57
9
65
12
7
0.85
0.49
0.39
0.56
(NiFeSe_Hases)(Oxidored_q6)_(NiFe_hyd_SSU_C)
22
C2
A2B2
7
24
38
21
117
38
3
0.87
0.92
0.58
0.92
(P53_TAD)(SWIB)
1
C1
AB
6
6
10
6
10
6
0
1.00
0.70
1.00
1.00
(PDZ)_(Annexin)_(Annexin)_(Annexin)_(Annexin)(peptide)
1
C1
AB
7
11
12
6
18
10
60
1.00
1.00
0.25
1.00
(PHD)(peptide)
12
C2
A2B2
5
35
6
4
59
35
12
0.83
0
0
0
(Phe_tRNA-synt_N)_(tRNA-synt_2d)(tRNA_bind)_(B3_4)_(B5)_(tRN A_synthFbeta)_(FDX-ACB)
8
C2
A2B2
9
9
27
16
27
16
9
1.00
1.00
0.63
0.96
(PI3K_p85B)_(PI3K_rbd)_(PI3K_C2)_(PI3Ka)_(PI3_PI4_kinase)(SH 2)_(PI3K_P85_iSH2)
1
C1
AB
5
6
39
3
41
3
94
1.00
1.00
1.00
1.00
(PI3K_p85B)_(PI3K_rbd)_(PI3K_C2)_(PI3Ka)_(PI3_PI4_kinase)(SH 3_9)_(RhoGAP)_(SH2)_(PI3K_P85_iSH2)_(SH2)
1
C1
AB
7
8
7
3
8
3
42
1.00
1.00
1.00
1.00
(Pico_P1A)(Rhv)
1
C1
AB3
72
77
141
83
148
86
0
0.97
0.91
0.04
0.85
(Pico_P1A)(Rhv)
2
C5
AB3
13
77
33
28
148
86
0
0.81
0.15
0.03
0.24
(Pico_P1A)(Rhv)
3
C3
AB3
10
77
25
22
148
86
0
0.76
0
0.04
0.28
(Pico_P1A)_(Rhv)(Rhv)
1
C5
AB2
13
18
17
14
22
18
5
1.00
0.71
0.59
0.65
(PRMT5_TIM)_(PRMT5)_(PRMT5_C)(WD40)_(WD40)_(WD40)_(WD40)_(WD 40)_(WD40)
4
C2
A2B2
5
7
45
2
48
2
97
0.71
0
0
0.09
(PRMT5_TIM)_(PRMT5)_(PRMT5_C)(WD40)_(WD40)_(WD40)_(WD40)_(WD 40)_(WD40)
5
C2
A2B2
5
7
45
2
48
2
97
0.71
0.02
0
0.09
(PRMT5_TIM)_(PRMT5)_(PRMT5_C)(WD40)_(WD40)_(WD40)_(WD40)_(WD 40)_(WD40)
6
C2
A2B2
5
7
45
2
48
2
97
0.71
0
0
0.09
(PRMT5_TIM)_(PRMT5)_(PRMT5_C)(WD40)_(WD40)_(WD40)_(WD40)_(WD 40)_(WD40)
7
C2
A2B2
5
7
45
2
48
2
97
0.71
0
0
0.09
(PRMT5_TIM)_(PRMT5)_(PRMT5_C)(WD40)_(WD40)_(WD40)_(WD40)_(WD 40)_(WD40)
8
C2
A2B2
5
7
45
2
48
2
97
0.71
0
0
0.09
(PRMT5_TIM)_(PRMT5)_(PRMT5_C)(WD40)_(WD40)_(WD40)_(WD40)_(WD 40)_(WD40)
15
D2
A4B4
6
7
47
2
48
2
97
0.85
0.26
0.96
0.55
(Proteasome)(Proteasome)_(Pr_beta_C)(Proteasome_A_N)_(Protea some)
1
C2
A12B2C14
28
28
242
142
242
142
5
1.00
1.00
0.07
0.91
(Rieske)_(Ring_hydroxyl_A)(Ring_hydroxyl_B)
32
C3
A3B3
16
18
52
26
54
28
3
1.00
1.00
1.00
0.50
(SH3_1)(peptide)
1
C1
AB
42
50
86
35
94
40
0
0.95
0.85
0.26
0.80
(Skp1_POZ)(ubiquitin)(VHL)_(VHL_C)
1
C1
ABC
5
5
38
3
44
3
3
1.00
1.00
0.16
1.00
(Vinculin)(peptide)
7
C2
A2B2
8
25
8
1
25
5
0
0.80
0
0
0.13
(Vinculin)(peptide)
8
C2
A2B2
8
25
8
1
25
5
0
0.80
0
0
0
(V-set)_(C1-set)(V-set_2)_(C1-set)
1
C1
AB
86
86
92
18
92
18
12
1.00
1.00
0.93
0.88
(V-set)_(C1-set)(peptide)
634
C2
A4B2
7
263
19
1
546
42
0
1.00
0
0
0.05
(V-set)_(C1-set)(peptide)
635
C2
A4B2
7
263
8
2
546
42
0
1.00
0.13
0
0.13
(WH1)(peptide)
1
C1
AB
7
11
11
5
16
6
5
0.77
0.82
0.09
0.64
(S_100)_(EF-hand_1)(peptide)
10
C1
A2B
7
18
9
2
25
11
0
0.87
1.00
0
1.00
(7tm_1)(G-alpha)(G-gamma)(Myc-LZ)_(WD40)_(WD40)_(WD40)_(WD40 )_(WD40)_(WD40)(V-set)_(V-set)
1
C1
ABCDE
8
11
8
10
11
12
3
1.00
1.00
0
1.00
(AAA)_(Rep_fac_C)(BRCT)_(AAA)_(RFC1)(DNA_pol3_delta2)_(Rep_f ac_C)(PCNA_N)_(PCNA_C)
1
unknown
A3BCD3
11
11
11
7
11
7
3
1.00
1.00
0.45
1.00
(14-3-3)(peptide)
1
C1
AB
79
101
368
15
431
18
9
0.87
0.04
0.64
0.12
(Aph-1)(Ncstrn_small)_(Nicastrin)(PEN-2)(Presenilin)
1
C1
ABCD
7
8
7
4
8
4
2
1.00
1.00
0.86
1.00
(Bcl-2)(BID)
1
C1
AB
9
10
12
10
13
11
0
1.00
0.75
0.75
0.58
(bCoV_S1_N)_(bCoV_S1_RBD)(Peptidase_M2)
1
C1
AB
19
27
22
6
33
11
8
0.86
1.00
0.05
0.86
(bCoV_S1_N)_(bCoV_S1_RBD)(Peptidase_M2)_(Collectrin)
1
C1
AB
6
9
6
7
9
10
23
1.00
1.00
0
0.83
(BTB)(peptide)
1
C1
AB
6
7
24
2
36
2
6
1.00
0
0
0
(BTB)(peptide)
2
C1
AB
5
7
22
2
36
2
6
0.83
0
0
0
(C1-set)(MHC_I)_(C1-set)_(MHC_I_C)(peptide)
1
C1
ABC
9
12
15
9
19
9
0
0.90
1.00
0
0.87
(C1-set)(MHC_I_3)_(C1-set)
1
C1
AB
19
19
66
14
67
14
9
1.00
1.00
1.00
0.86
(CoV_peptidase)(ubiquitin)
1
C1
AB
15
18
18
16
21
17
9
0.88
1.00
0.56
0.89
(E1-E2_ATPase)_(Hydrolase)(KdpA)(KdpC)(peptide)
1
C1
ABCD
10
19
10
5
19
5
3
1.00
1.00
0.70
1.00
(E1-E2_ATPase)_(Hydrolase)(KdpA)(KdpC)(Potass_KdpF)
1
C1
ABCD
10
19
10
6
19
6
3
1.00
1.00
0.70
1.00
(EGF)(Recep_L_domain)_(Furin-like)_(Recep_L_domain)_(GF_rece p_IV)
1
C1
AB
7
11
11
9
15
10
22
1.00
0.64
0.18
0.45
(EGF)(Recep_L_domain)_(Furin-like)_(Recep_L_domain)_(GF_rece p_IV)
2
C2
A2B2
5
11
8
8
15
10
22
0.71
0.75
0.88
0.75
(GP120)(GP41)
1
C1
AB
5
6
5
2
6
4
19
1.00
0
1.00
0.80
(GP120)(GP41)
2
C1
AB
5
6
5
2
6
4
21
1.00
0
0
0.80
(GP120)(GP41)(V-set)
1
C1
ABC2
5
21
5
1
21
10
100
1.00
1.00
0
1.00
(GP120)(V-set)_(C1-set)
1
C1
AB2
20
70
22
11
79
43
2
0.78
1.00
0.45
0.41
(HLH)_(PAS)_(PAS_11)(HLH)_(PAS)_(PAS_3)
1
C1
AB
5
7
6
5
8
7
37
1.00
1.00
0.50
1.00
(IBB)_(Arm)_(Arm)_(Arm)_(Arm)_(Arm)_(Arm)_(Arm)_(Arm)_(Arm_3 )(peptide)
1
C1
AB
21
34
42
4
78
6
9
0.75
1.00
0.93
0.93
(Kelch_1)_(Kelch_1)_(Kelch_1)_(Kelch_1)_(Kelch_1)_(Kelch_1)( peptide)
1
C1
AB
8
14
15
3
22
6
11
0.88
1.00
0.80
0.73
(Lipoprotein_18)(POTRA)_(POTRA)_(POTRA)_(POTRA)_(POTRA)_(Omp 85)(PQQ_2)_(PQQ_3)_(PQQ_3)(SmpA_OmlA)(YfiO)
1
C1
ABCDE
28
29
29
12
30
15
0
1.00
1.00
0.79
0.93
(SH2)(peptide)
15
C2
A2B2
9
69
21
1
125
38
80
0.90
0.57
0.90
0.76
(SWIB)(peptide)
1
C1
AB
30
31
49
4
51
4
0
1.00
0.88
0.98
0.65
(ubiquitin)(UCH)
1
C1
AB
19
24
28
17
36
25
3
1.00
0.93
0.79
0.71
(V-set)(peptide)
2
C1
AB
6
40
6
2
51
15
0
1.00
0.67
0.17
0.67